期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 91, 页码 11211-11213出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36197c
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资金
- Grants-in-Aid for Scientific Research [21106002, 21106001, 12J05642] Funding Source: KAKEN
We found that an integrated flow microreactor system enables the preparation of boronic esters bearing electrophilic functional groups using organolithium chemistry and that it allows for their use in Suzuki-Miyaura cross-coupling without intentionally added base. Based on this method, cross-coupling of two aryl halides bearing electrophilic functional groups was accomplished to obtain the corresponding biaryl compounds in one flow.
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