Detection of exosomal prions in blood by immunochemistry techniques

First Demonstration of Transmissible Spongiform Encephalopathy-associated Prion Protein (PrPTSE) in Extracellular Vesicles from Plasma of Mice Infected with Mouse-adapted Variant Creutzfeldt-Jakob Disease byin VitroAmplification

(2014) Paula Saá et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Factors intrinsic and extrinsic to blood hamper the development of a routine blood test for human prion diseases

(2014) H. Abdel-Haq   JOURNAL OF GENERAL VIROLOGY

Exosomes: the ideal nanovectors for biodelivery

(2012) Stefano Fais et al.   BIOLOGICAL CHEMISTRY

Prion-infected cells regulate the release of exosomes with distinct ultrastructural features

(2012) Bradley M. Coleman et al.   FASEB JOURNAL

Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay

(2011) Julie Ann Edgeworth et al.   LANCET

Transmission of sporadic Creutzfeldt-Jakob disease by blood transfusion: risk factor or possible biases

(2011) Maria Puopolo et al.   TRANSFUSION

Prion Disease Blood Test Using Immunoprecipitation and Improved Quaking-Induced Conversion

(2011) C. D. Orru et al.   mBio

Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles

(2008) Sandrine Alais et al.   BIOLOGY OF THE CELL

Prion diseases are efficiently transmitted by blood transfusion in sheep

(2008) F. Houston et al.   BLOOD