Article
Chemistry, Organic
Naveen J. J. Roy, Parappa L. L. Pujari, Pinaki Talukdar
Summary: This article assesses the transmembrane anion transport activity of substituted pyrrole-2-carboxamides and demonstrates their highly tuneable and versatile nature for anion transport through simple variations of the pyrrole ring and amide substituents.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Business, Finance
Emmanuel Jordy Menvouta, Sven Serneels, Tim Verdonck
Summary: Non-fungible tokens (NFT) are a novel asset class with potential to diversify portfolios. Limited research supports this hypothesis at a collection level, and it remains uncertain how to practically leverage this potential. Due to their non-fungible nature, the liquidity of NFTs, which is essential for a mathematically optimal portfolio, is not always available. This letter introduces a practical portfolio optimization strategy for NFTs using machine learning, specifically robust hierarchical risk parity. The inclusion of high valued NFT collections in portfolios has been shown to improve overall portfolio returns.
FINANCE RESEARCH LETTERS
(2023)
Article
Chemistry, Physical
Donglei Bu, Duocheng Bu, Wei Chen, Changgeng Huang, Libo Li, Hao Lei, Shaoming Huang
Summary: Three new Cu-X-bpy (X = Cl/Br, Cl/I or Br/I) photocatalytic materials were synthesized and their hydrogen production performance was systematically investigated. It was found that the hydrogen productivity can be significantly enhanced by varying the anions in the materials.
JOURNAL OF CATALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Wutong Du, Jin Tong, Wei Deng, Mingxue Wang, Shuyan Yu
Summary: Two types of palladium(II)-based metallacalixarenes were synthesized through coordination-driven self-assembly from flexible pyridine-bridged diimidazole ligands and palladium(II)-based building blocks. The structures were characterized using NMR spectroscopy and single crystal X-ray diffraction analysis, showing unique single and double bowl-shape structures.
CHINESE CHEMICAL LETTERS
(2021)
Article
Materials Science, Coatings & Films
Shuang Zhang, Chuang Dong, Peter Haeussler
Summary: This article discusses the spherical-periodic order in the pair-correlation functions of crystalline systems, using simple crystal structures as examples. The spherical-periodic picture helps to understand the atomic density distribution and charge-neutral entities in crystal structures.
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A
(2022)
Article
Cell Biology
Tomohiro Iriki, Hiroaki Iio, Shu Yasuda, Shun Masuta, Masakazu Kato, Hidetaka Kosako, Shoshiro Hirayama, Akinori Endo, Fumiaki Ohtake, Mako Kamiya, Yasuteru Urano, Yasushi Saeki, Jun Hamazaki, Shigeo Murata
Summary: Proteasome plays a role in senescent cells by forming nuclear foci with liquid-like properties. These foci, known as senescence-associated nuclear proteasome foci (SANPs), require ubiquitination, RAD23B, and proteasome activity for their formation. Knock-down of RAD23B suppresses SANP formation and alters mitochondrial activity, resulting in increased reactive oxygen species production.
Article
Chemistry, Multidisciplinary
Shohei Shimizu, Hiroaki Yoshida, Koichi Mayumi, Hiroharu Ajiro, Yoshimitsu Sagara
Summary: Mechanochromic mechanophores have been introduced into polymer materials to visualize applied mechanical force. Hydrogels with mechanophores such as 1,2-dioxetane derivatives, spiropyran, and rhodamine have been developed, but lack instantaneous reversibility. This study demonstrates the use of cyclophane-based supramolecular mechanophores in hydrogels to achieve reversible changes in luminescence without breaking covalent bonds. The mechanochromic luminescence is caused by a decrease in intramolecular excimers upon deformation, and the incorporation of mechanophores into the hydrophobic part of the hydrogel was observed when dimethylsulfoxide was replaced with water.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Shuyu Dong, Zhiwu Yu, Liecheng Guo, Yuting Yang, Changzheng Tu, Rajamani Krishna, Feng Luo
Summary: Precise ion recognition is crucial for anionic decontamination in water. However, current anionic recognition methods have limitations, such as narrow application scope in organic solvent for neutral receptors and poor selectivity for cationic receptors. Researchers have now introduced a neutral metal-organic framework (MOF) anion receptor that enables precise anion recognition, even in the presence of competitive anions. A radical-dominating mechanism is proposed to explain the efficacy of the neutral MOF.
Article
Biochemistry & Molecular Biology
Patryk Niedbala, Kajetan Dabrowa, Agnieszka Cholewiak-Janusz, Janusz Jurczak
Summary: This study presents the synthesis and anion binding studies of a family of homologous molecular receptors based on a DITIPIRAM platform. The host-guest system offers multiple NH hydrogen bond donors to anions, forming stable complexes with carboxylates and chloride anions even in competitive solvent mixtures. Receptors 5 and 6 containing electron-withdrawing F- and -CF3 para-substituents were found to be the most effective derivatives in the series.
Article
Multidisciplinary Sciences
Maria C. Basil, Fabian L. Cardenas-Diaz, Jaymin J. Kathiriya, Michael P. Morley, Justine Carl, Alexis N. Brumwell, Jeremy Katzen, Katherine J. Slovik, Apoorva Babu, Su Zhou, Madison M. Kremp, Katherine B. McCauley, Shanru Li, Joseph D. Planer, Shah S. Hussain, Xiaoming Liu, Rebecca Windmueller, Yun Ying, Kathleen M. Stewart, Michelle Oyster, Jason D. Christie, Joshua M. Diamond, John F. Engelhardt, Edward Cantu, Steven M. Rowe, Darrell N. Kotton, Harold A. Chapman, Edward E. Morrisey
Summary: This study reveals the existence of a unique population of secretory cells in the respiratory bronchioles of the human lung, which act as unidirectional progenitors for alveolar type 2 cells. The differentiation of these respiratory airway secretory cells into alveolar type 2 cells is regulated by Notch and Wnt signaling. These findings highlight the importance of this distinct progenitor cell population in maintaining the gas-exchange compartment and its potential role in chronic lung diseases.
Article
Computer Science, Artificial Intelligence
Yang Liu, Anthony C. Constantinou
Summary: Learning from data with missing values is a common phenomenon in many domains. However, few Bayesian Network structure learning algorithms consider missing data, and those that do often assume missing data are missing at random. This paper proposes three variants of greedy search structure learning that effectively deal with systematically missing data. Empirical investigations demonstrate that the proposed approach outperforms the commonly used Structural EM algorithm in terms of accuracy and efficiency, regardless of whether the data is missing at random or not.
Article
Chemistry, Multidisciplinary
Anita Nehra, Apoorva Malik, Pragati R. Sharma, Sateesh Bandaru, Rakesh K. Sharma
Summary: A neutral electron-deficient, pentafluorophenyl hydrazone-functionalized calix[4]arene, R, was able to visually detect fluoride out of 19 anions. The formation of R + F- was confirmed by UV-vis, H-1 & F-19 NMR, and ESI-MS studies. Variable temperature NMR studies revealed the formation of HF2-. DFT and TD-DFT studies demonstrated strong binding interactions between R and F-.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Krystyna Maslowska-Jarzyna, Maria L. Korczak, Jakub A. Wagner, Michal J. Chmielewski
Summary: The study describes the synthesis of 1,8-diaminocarbazoles with electron-withdrawing substituents, leading to enhanced anion affinities and acidities in the resulting receptors. The newly developed colorimetric anion sensor showed vivid color and fluorescence changes upon addition of basic anions, but exhibited poor selectivity due to the dominant proton transfer interaction with most anions. These highly acidic and strongly binding receptors may have potential applications in organocatalysis or pH-switchable anion transport through lipophilic membranes.
Article
Pharmacology & Pharmacy
Conor J. Bloxham, Katina D. Hulme, Fabrizio Fierro, Christian Fercher, Cassandra L. Pegg, Shannon L. O'Brien, Simon R. Foster, Kirsty R. Short, Sebastian G. B. Furness, Melissa E. Reichelt, Masha Y. Niv, Walter G. Thomas
Summary: Bitter taste receptors (T2Rs) are a type of G protein-coupled receptors that allow humans to detect aversive and toxic substances. This study characterized the functional properties of previously identified T2Rs in human cardiac tissues and their naturally occurring polymorphisms. The results showed differences in signaling among different T2R variants, and revealed a potential association between the T2R50 Tyr203 variant and cardiovascular disease.
BIOCHEMICAL PHARMACOLOGY
(2024)
Article
Spectroscopy
Kumaresan Murugesan, Vanthana Jeyasingh, Sudha Lakshminarayanan, Narayanan Selvapalam, Geetha Dass, Lakshminarayanan Piramuthu
Summary: A new hydrazine-based sensor L has been designed and synthesized, which can detect cyanide through ABIFE and fluoride through ABRFE. The sensor L shows almost the same sensing performance for other tested anions as well.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Daniele Merli, Sonia La Cognata, Federica Balduzzi, Ana Miljkovic, Lucio Toma, Valeria Amendola
NEW JOURNAL OF CHEMISTRY
(2018)
Article
Chemistry, Organic
Anna B. Aletti, Ana Miljkovic, Lucio Toma, Rosaria Bruno, Donatella Armentano, Thorfinnur Gunnlaugsson, Greta Bergamaschi, Valeria Amendola
JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Ana Miljkovic, Sonia La Cognata, Greta Bergamaschi, Mauro Freccero, Antonio Poggi, Valeria Amendola
Review
Chemistry, Multidisciplinary
Sonia La Cognata, Ana Miljkovic, Riccardo Mobili, Greta Bergamaschi, Valeria Amendola
Article
Chemistry, Multidisciplinary
Marcia Dominguez, Juan F. Blandez, Beatriz Lozano-Torres, Cristina de la Torre, Maurizio Licchelli, Carlo Mangano, Valeria Amendola, Felix Sancenon, Ramon Martinez-Manez
Summary: Benzene is a highly toxic aromatic hydrocarbon with metabolization products causing various health issues, necessitating the development of reliable and rapid detection methods. This study reports a nanodevice for quantitative analysis of t,t-MA in urine using a simple fluorimeter for quick detection.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Sonia La Cognata, Riccardo Mobili, Francesca Merlo, Andrea Speltini, Massimo Boiocchi, Teresa Recca, Louis J. Maher, Valeria Amendola
Article
Biochemistry & Molecular Biology
Marcello Monteleone, Riccardo Mobili, Chiara Milanese, Elisa Esposito, Alessio Fuoco, Sonia La Cognata, Valeria Amendola, Johannes C. Jansen
Summary: Membrane-based processes are increasingly important for sustainable and energy-efficient gas separation applications. This study found that different organic cage fillers dispersed in poly(ether ether ketone) have varying effects on gas diffusion coefficients and selectivity. Specifically, furanyl imine cages significantly increased diffusion coefficients of bulkier gases, while m-xylyl imine cages improved size selectivity.
Article
Chemistry, Multidisciplinary
Riccardo Mobili, Giovanni Preda, Sonia La Cognata, Lucio Toma, Dario Pasini, Valeria Amendola
Summary: A chiral cage is proposed as an effective chiroptical sensor for detecting perrhenate in water, fruit juice, and artificial urine media. The key mechanism for chiroptical sensing involves changes in the dihedral angle of the binaphthyl unit and H-bonding with the guest, leading to significant changes in the CD signal.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Sonia La Cognata, Riccardo Mobili, Chiara Milanese, Massimo Boiocchi, Mattia Gaboardi, Donatella Armentano, Johannes C. Jansen, Marcello Monteleone, Ariana R. Antonangelo, Mariolino Carta, Valeria Amendola
Summary: Two novel imide/imine-based organic cages were prepared and studied as materials for selective separation of CO2 from N-2 and CH4. The cages showed selectivity for CO2 over N-2 and CH4 in gas adsorption and membrane filling, leading to improved gas transport properties and CO2 selectivity in mixed-matrix membranes.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Valentina Gazzola, Pietro Grisoli, Valeria Amendola, Giacomo Dacarro, Carlo Mangano, Piersandro Pallavicini, Antonio Poggi, Silvia Rossi, Barbara Vigani, Angelo Taglietti
Summary: This paper reports on the preparation of Imidazole-functionalized glass surfaces and demonstrates the use of a dinuclear Cu(II) complex to interact with deprotonated grafted imidazole moieties. This supramolecular approach leads to the development of an antimicrobial surface with a strong microbicidal effect using low amounts of the copper complex.
Article
Pharmacology & Pharmacy
Dalila Miele, Milena Sorrenti, Laura Catenacci, Paolo Minzioni, Giorgio Marrubini, Valeria Amendola, Marcello Maestri, Paolo Giunchedi, Maria Cristina Bonferoni
Summary: In this study, poly lactic-co-glycolic acid (PLGA) based nanoparticles (NPs) were proposed as carriers for indocyanine green (ICG), and fluorescence quenching experiments were conducted by studying the interaction between ICG and chitosan oleate (CS-OA). The results showed that associating ICG with NPs can reduce cell viability after laser irradiation, opening up new possibilities for utilizing PDT mechanism in cancer therapy.
Review
Chemistry, Multidisciplinary
Sonia La Cognata, Valeria Amendola
Summary: Organic cages have attracted great interest in the scientific community due to their unique features, such as simple synthesis, structural tunability, and high selectivity. In the past decade, organic cages have been extensively studied and applied as chemosensors, separation agents, and membrane materials.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Sonia La Cognata, Donatella Armentano, Nicoletta Marchesi, Pietro Grisoli, Alessia Pascale, Marion Kieffer, Angelo Taglietti, Anthony P. Davis, Valeria Amendola
Summary: This study reports a novel organic cage as a potential antimicrobial and antifungal agent. Experimental results demonstrate that the cage can bind and transport specific anions and exhibit antimicrobial activity against Staphylococcus aureus.
CHEMISTRY-SWITZERLAND
(2022)
Article
Chemistry, Inorganic & Nuclear
Alexiane Thevenet, Ana Miljkovic, Sonia La Cognata, Cecile Marie, Christelle Tamain, Nathalie Boubals, Carlo Mangano, Valeria Amendola, Philippe Guilbaud
Summary: The addition of complexing agents in nitric acid solutions improves the complexation strength towards pertechnetate anion and successfully retains it in the aqueous phase, showing potential for application in solvent extraction processes.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Alexiane Thevenet, Cecile Marie, Christelle Tamain, Valeria Amendola, Ana Miljkovic, Dominique Guillaumont, Nathalie Boubals, Philippe Guilbaud
DALTON TRANSACTIONS
(2020)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
