Human distal airways contain a multipotent secretory cell that can regenerate alveoli

Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration

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Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells

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In Vitro and In Vivo Development of the Human Airway at Single-Cell Resolution

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Airway Remodeling in Ferrets with Cigarette Smoke Induced COPD using µCT Imaging

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The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future

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Small airway loss in the physiologically ageing lung: a cross-sectional study in unused donor lungs

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Excess mucus viscosity and airway dehydration impact COPD airway clearance

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Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells

(2019) Anjali Jacob et al.   Nature Protocols

Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

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Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells

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(2018) Hyun-Kyoung Koo et al.   Lancet Respiratory Medicine

Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium

(2018) Katherine B. McCauley et al.   Stem Cell Reports

Clustering trees: a visualisation for evaluating clusterings at multiple resolutions

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A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

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Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

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A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

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Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells

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A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma

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HSPA6 is an ulcerative colitis susceptibility factor that is induced by cigarette smoke and protects intestinal epithelial cells by stabilizing anti-apoptotic Bcl-XL

(2016) Anouk Regeling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Advances in Understanding Bronchiolitis Obliterans After Lung Transplantation

(2016) Stijn E. Verleden et al.   CHEST

Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation

(2016) David B. Frank et al.   Cell Reports

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The Site and Nature of Airway Obstruction after Lung Transplantation

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Secreted Phosphoprotein 1 Is a Determinant of Lung Function Development in Mice

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Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

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Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells

(2014) Shimpei Gotoh et al.   Stem Cell Reports

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Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

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Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

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Notch signaling promotes airway mucous metaplasia and inhibits alveolar development

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