Neutrophil extracellular traps in cancer progression

Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression

(2013) Inbal Mishalian et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Monitoring tumor-derived cell-free DNA in patients with solid tumors: Clinical perspectives and research opportunities

(2013) Angela Esposito et al.   CANCER TREATMENT REVIEWS

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

(2013) Jonathan Cools-Lartigue et al.   JOURNAL OF CLINICAL INVESTIGATION

The metastasis-promoting roles of tumor-associated immune cells

(2013) Heath A. Smith et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Lipopolysaccharide-induced toll-like receptor 4 signaling enhances the migratory ability of human esophageal cancer cells in a selectin-dependent manner

(2013) Mathieu C. Rousseau et al.   SURGERY

Defective Stromal Remodeling and Neutrophil Extracellular Traps in Lymphoid Tissues Favor the Transition from Autoimmunity to Lymphoma

(2013) S. Sangaletti et al.   Cancer Discovery

A proposed role for neutrophil extracellular traps in cancer immunoediting

(2013) Sivan Berger-Achituv et al.   Frontiers in Immunology

Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies

(2012) T. A. Fuchs et al.   BLOOD

Neutrophils Promote Liver Metastasis via Mac-1–Mediated Interactions with Circulating Tumor Cells

(2012) Jonathan D. Spicer et al.   CANCER RESEARCH

Tumor-associated neutrophils: friend or foe?

(2012) Z. G. Fridlender et al.   CARCINOGENESIS

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis

(2012) Braedon McDonald et al.   Cell Host & Microbe

Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase

(2012) Thomas Große-Steffen et al.   Clinical & Developmental Immunology

Polymorphonuclear neutrophils promote dyshesion of tumor cells and elastase-mediated degradation of E-cadherin in pancreatic tumors

(2012) Matthias M. Gaida et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Clathrin Pit-mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Cancer Cells

(2012) Alyssa D. Gregory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

Cathepsin G Induces Cell Aggregation of Human Breast Cancer MCF-7 Cells via a 2-Step Mechanism: Catalytic Site-Independent Binding to the Cell Surface and Enzymatic Activity-Dependent Induction of the Cell Aggregation

(2012) Riyo Morimoto-Kamata et al.   MEDIATORS OF INFLAMMATION

Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils

(2012) Zvi G. Fridlender et al.   PLoS One

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

(2012) M. Demers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protumor and antitumor functions of neutrophil granulocytes

(2012) Sven Brandau et al.   Seminars in Immunopathology

Neutrophil elastase activity in pulmonary venous blood during lung resection

(2012) Y. Nagamatsu et al.   Interactive Cardiovascular and Thoracic Surgery

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

Perioperative use of a neutrophil elastase inhibitor in video-assisted thoracoscopic oesophagectomy for cancer

(2011) H. Makino et al.   BRITISH JOURNAL OF SURGERY

LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases  1 Integrin-Mediated Cell Adhesion and Liver Metastasis

(2011) R. Y. C. Hsu et al.   CANCER RESEARCH

On the dual roles and polarized phenotypes of neutrophils in tumor development and progression

(2011) H. Piccard et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment

(2011) Shawn Rose et al.   CYTOMETRY PART A

The historical milestones in the understanding of leukocyte biology initiated by Elie Metchnikoff

(2011) Jean-Marc Cavaillon   JOURNAL OF LEUKOCYTE BIOLOGY

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

Neutrophil Elastase Enhances Sputum Solubilization in Cystic Fibrosis Patients Receiving DNase Therapy

(2011) Venizelos Papayannopoulos et al.   PLoS One

Identification of citrullinated histone H3 as a potential serum protein biomarker in a lethal model of lipopolysaccharide-induced shock

(2011) Yongqing Li et al.   SURGERY

Optimal Period for the Prophylactic Administration of Neutrophil Elastase Inhibitor for Patients with Esophageal Cancer Undergoing Esophagectomy

(2011) Makoto Iwahashi et al.   WORLD JOURNAL OF SURGERY

Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I

(2010) Olga Patutina et al.   BIOCHIMIE

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

(2010) K. D. Metzler et al.   BLOOD

Transiently Entrapped Circulating Tumor Cells Interact with Neutrophils to Facilitate Lung Metastasis Development

(2010) S. J. Huh et al.   CANCER RESEARCH

Plasma Nucleosome Levels Might Predict Response to Therapy in Patients With Advanced Non–Small-Cell Lung Cancer

(2010) Sachin Kumar et al.   Clinical Lung Cancer

Neutrophils: Cinderella of innate immune system

(2010) V. Kumar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth

(2010) A McGarry Houghton et al.   NATURE MEDICINE

Antimicrobial peptides: The ancient arm of the human immune system

(2010) Jochen Wiesner et al.   Virulence

Neutrophil Extracellular Traps: How to Generate and Visualize Them

(2010) Volker Brinkmann et al.   Jove-Journal of Visualized Experiments

Innate Immune Cells Induce Hemorrhage in Tumors during Thrombocytopenia

(2009) Benoit Ho-Tin-Noé et al.   AMERICAN JOURNAL OF PATHOLOGY

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Cathepsin G-mediated enhanced TGF-β signaling promotes angiogenesis via upregulation of VEGF and MCP-1

(2009) Thomas J. Wilson et al.   CANCER LETTERS

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

Prospective randomized controlled study on the effects of perioperative administration of a neutrophil elastase inhibitor to patients undergoing video-assisted thoracoscopic surgery for thoracic esophageal cancer

(2009) Y. Kawahara et al.   DISEASES OF THE ESOPHAGUS

Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms

(2009) Braedon McDonald et al.   INTERNATIONAL JOURNAL OF CANCER

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

DNase I Inhibits a Late Phase of Reactive Oxygen Species Production in Neutrophils

(2009) Daniela B. Munafo et al.   Journal of Innate Immunity

Regulation of Extracellular Chromatin Release from Neutrophils

(2009) Indira Neeli et al.   Journal of Innate Immunity

Depletion of Ly6G/Gr-1 Leukocytes after Spinal Cord Injury in Mice Alters Wound Healing and Worsens Neurological Outcome

(2009) D. P. Stirling et al.   JOURNAL OF NEUROSCIENCE

NETs: a new strategy for using old weapons

(2009) Venizelos Papayannopoulos et al.   TRENDS IN IMMUNOLOGY

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Two-dimensional kinetics of β2-integrin and ICAM-1 bindings between neutrophils and melanoma cells in a shear flow

(2008) Shile Liang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Quantitative and qualitative characterization of plasma DNA identifies primary and recurrent colorectal cancer

(2008) M. Frattini et al.   CANCER LETTERS

Cathepsin G Enhances Mammary Tumor-Induced Osteolysis by Generating Soluble Receptor Activator of Nuclear Factor- B Ligand

(2008) T. J. Wilson et al.   CANCER RESEARCH

Effects of the Tumor-Leukocyte Microenvironment on Melanoma–Neutrophil Adhesion to the Endothelium in a Shear Flow

(2008) Shile Liang et al.   Cellular and Molecular Bioengineering

CANCER: The Metastasis Cascade

(2008) C. A. Klein   SCIENCE

Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions

(2007) Brice Korkmaz et al.   BIOCHIMIE