Antiviral strategies against influenza virus: towards new therapeutic approaches

Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors

(2013) Joseph D. Bauman et al.   ACS Chemical Biology

Structure-Based Discovery of the Novel Antiviral Properties of Naproxen against the Nucleoprotein of Influenza A Virus

(2013) Nathalie Lejal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions

(2013) Giorgio Palù et al.   ANTIVIRAL RESEARCH

A small molecule multi-kinase inhibitor reduces influenza A virus replication by restricting viral RNA synthesis

(2013) Luis Martinez-Gil et al.   ANTIVIRAL RESEARCH

The use of sialidase therapy for respiratory viral infections

(2013) John M. Nicholls et al.   ANTIVIRAL RESEARCH

Combination of MEK inhibitors and oseltamivir leads to synergistic antiviral effects after influenza A virus infection in vitro

(2013) Emanuel Haasbach et al.   ANTIVIRAL RESEARCH

Influenza virus resistance to neuraminidase inhibitors

(2013) Mélanie Samson et al.   ANTIVIRAL RESEARCH

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation

(2013) Daniela Meyer et al.   BIOCHEMICAL JOURNAL

Discovery and synthesis of novel benzofurazan derivatives as inhibitors of influenza A virus

(2013) Ulrich Kessler et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lessons from Lipids in the Fight against Influenza

(2013) Adolfo García-Sastre   CELL

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation

(2013) Vincent C. Tam et al.   CELL

The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance

(2013) Christina Ehrhardt et al.   CELLULAR MICROBIOLOGY

Structure and assembly of the influenza A virus ribonucleoprotein complex

(2013) Wenjie Zheng et al.   FEBS LETTERS

Sialylneolacto-N-tetraose c (LSTc)-bearing Liposomal Decoys Capture Influenza A Virus

(2013) Gabriel L. Hendricks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of Novel Dual Inhibitors of the Wild-Type and the Most Prevalent Drug-Resistant Mutant, S31N, of the M2 Proton Channel from Influenza A Virus

(2013) Jizhou Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly

(2013) Serena Massari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Serum- and Glucocorticoid-Regulated Kinase 1 Is Required for Nuclear Export of the Ribonucleoprotein of Influenza A Virus

(2013) J. G. Alamares-Sapuay et al.   JOURNAL OF VIROLOGY

SUMOylation Affects the Interferon Blocking Activity of the Influenza A Nonstructural Protein NS1 without Affecting Its Stability or Cellular Localization

(2013) A. Santos et al.   JOURNAL OF VIROLOGY

Nucleozin Targets Cytoplasmic Trafficking of Viral Ribonucleoprotein-Rab11 Complexes in Influenza A Virus Infection

(2013) M. J. Amorim et al.   JOURNAL OF VIROLOGY

Serum Amyloid P Is a Sialylated Glycoprotein Inhibitor of Influenza A Viruses

(2013) Emma R. Job et al.   PLoS One

Nonstructural Protein 1 of Influenza A Virus Interacts with Human Guanylate-Binding Protein 1 to Antagonize Antiviral Activity

(2013) Zixiang Zhu et al.   PLoS One

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

(2013) Jun Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How academic labs can approach the drug discovery process as a way to synergize with big pharma

(2013) Arianna Loregian et al.   TRENDS IN MICROBIOLOGY

Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity

(2013) Marie-Line Goulet et al.   PLoS Pathogens

Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice

(2013) Bastian Hatesuer et al.   PLoS Pathogens

Monomeric Nucleoprotein of Influenza A Virus

(2013) Sylvie Chenavas et al.   PLoS Pathogens

Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching

(2012) Hui-Chen Hung et al.   ANALYTICAL CHEMISTRY

Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses

(2012) Giulia Muratore et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action

(2012) Rossella Fioravanti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Influenza A virus-encoded NS1 virulence factor protein inhibits innate immune response by targeting IKK

(2012) Shijuan Gao et al.   CELLULAR MICROBIOLOGY

Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs

(2012) Enguang Feng et al.   ChemMedChem

A peptide derived from the C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly

(2012) Chunfeng Li et al.   FEBS Journal

Highly Potent Inhibitors of Proprotein Convertase Furin as Potential Drugs for Treatment of Infectious Diseases

(2012) Gero L. Becker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export

(2012) Liang Zhang et al.   JOURNAL OF CELL BIOLOGY

A novel family of peptides with potent activity against influenza A viruses

(2012) M. Q. Nicol et al.   JOURNAL OF GENERAL VIROLOGY

A Phase II Study of DAS181, a Novel Host Directed Antiviral for the Treatment of Influenza Infection

(2012) R. B. Moss et al.   JOURNAL OF INFECTIOUS DISEASES

Design, Synthesis, and in Vitro Biological Evaluation of 1H-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein

(2012) Huimin Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Contribution of Double-Stranded RNA and CPSF30 Binding Domains of Influenza Virus NS1 to the Inhibition of Type I Interferon Production and Activation of Human Dendritic Cells

(2012) I. Ramos et al.   JOURNAL OF VIROLOGY

Strain-Specific Contribution of NS1-Activated Phosphoinositide 3-Kinase Signaling to Influenza A Virus Replication and Virulence

(2012) J. Ayllon et al.   JOURNAL OF VIROLOGY

5'-Triphosphate-Short Interfering RNA: Potent Inhibition of Influenza A Virus Infection by Gene Silencing and RIG-I Activation

(2012) L. Lin et al.   JOURNAL OF VIROLOGY

Cross-neutralization of influenza A viruses mediated by a single antibody loop

(2012) Damian C. Ekiert et al.   NATURE

The RNA-binding domain of influenzavirus non-structural protein-1 cooperatively binds to virus-specific RNA sequences in a structure-dependent manner

(2012) Daniel Marc et al.   NUCLEIC ACIDS RESEARCH

Identification of Small Molecules with Type I Interferon Inducing Properties by High-Throughput Screening

(2012) Luis Martínez-Gil et al.   PLoS One

Polymer-attached zanamivir inhibits synergistically both early and late stages of influenza virus infection

(2012) C. M. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase

(2012) G. Muratore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organization of the Influenza Virus Replication Machinery

(2012) A. Moeller et al.   SCIENCE

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response

(2012) B. W. Jagger et al.   SCIENCE

Highly Conserved Protective Epitopes on Influenza B Viruses

(2012) C. Dreyfus et al.   SCIENCE

A Novel Small Molecule Inhibitor of Influenza A Viruses that Targets Polymerase Function and Indirectly Induces Interferon

(2012) Mila Brum Ortigoza et al.   PLoS Pathogens

Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease

(2012) Rebecca M. DuBois et al.   PLoS Pathogens

Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase

(2012) Eva Kowalinski et al.   PLoS Pathogens

Intravenous Peramivir for Treatment of Influenza A and B Virus Infection in High-Risk Patients

(2011) Shigeru Kohno et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Redox Regulation of the Influenza Hemagglutinin Maturation Process: A New Cell-Mediated Strategy for Anti-Influenza Therapy

(2011) Rossella Sgarbanti et al.   ANTIOXIDANTS & REDOX SIGNALING

Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo

(2011) Karoline Droebner et al.   ANTIVIRAL RESEARCH

Antiviral effect of a selective COX-2 inhibitor on H5N1 infection in vitro

(2011) Suki M.Y. Lee et al.   ANTIVIRAL RESEARCH

Structure-based discovery of anti-influenza virus A compounds among medicines

(2011) Mayuko Fukuoka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1

(2011) Joseph J. Jablonski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors

(2011) Lei You et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

High Mannose-binding Lectin with Preference for the Cluster of α1–2-Mannose from the Green AlgaBoodlea coactaIs a Potent Entry Inhibitor of HIV-1 and Influenza Viruses

(2011) Yuichiro Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring Organosilane Amines as Potent Inhibitors and Structural Probes of Influenza A Virus M2 Proton Channel

(2011) Jun Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M2

(2011) Jun Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

How Do Aminoadamantanes Block the Influenza M2 Channel, and How Does Resistance Develop?

(2011) Hadas Leonov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation and Comprehensive Analysis of an Influenza Virus Polymerase Cellular Interaction Network

(2011) L. Tafforeau et al.   JOURNAL OF VIROLOGY

Receptor Tyrosine Kinase Inhibitors Block Multiple Steps of Influenza A Virus Replication

(2011) N. Kumar et al.   JOURNAL OF VIROLOGY

Identification of influenza virus inhibitors which disrupt of viral polymerase protein–protein interactions

(2011) Geoffrey Chase et al.   METHODS

Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications

(2011) Noboru Uchide et al.   MOLECULES

Mechanism of Inhibition of Enveloped Virus Membrane Fusion by the Antiviral Drug Arbidol

(2011) Elodie Teissier et al.   PLoS One

Anti-Influenza Activity of Marchantins, Macrocyclic Bisbibenzyls Contained in Liverworts

(2011) Yuma Iwai et al.   PLoS One

Glycyrrhizin Exerts Antioxidative Effects in H5N1 Influenza A Virus-Infected Cells and Inhibits Virus Replication and Pro-Inflammatory Gene Expression

(2011) Martin Michaelis et al.   PLoS One

Increased Inflammatory Signaling and Lethality of Influenza H1N1 by Nuclear Thioredoxin-1

(2011) Young-Mi Go et al.   PLoS One

Inhibition of Influenza A Virus (H1N1) Fusion by Benzenesulfonamide Derivatives Targeting Viral Hemagglutinin

(2011) Lei Zhu et al.   PLoS One

Potent Neutralization of Influenza A Virus by a Single-Domain Antibody Blocking M2 Ion Channel Protein

(2011) Guowei Wei et al.   PLoS One

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

(2011) J. R. R. Whittle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

(2011) H.-H. Hoffmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors

(2011) Y.-F. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The host interactome of influenza virus presents new potential targets for antiviral drugs

(2011) Megan L. Shaw   REVIEWS IN MEDICAL VIROLOGY

A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins

(2011) D. Corti et al.   SCIENCE

A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

(2011) D. C. Ekiert et al.   SCIENCE

Emerging cellular targets for influenza antiviral agents

(2011) Konstantin H. Müller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Induction and evasion of type I interferon responses by influenza viruses

(2011) Adolfo García-Sastre   VIRUS RESEARCH

Advances in the Structure-Based Design of the Influenza A Neuraminidase Inhibitors

(2010) Petar Mitrasinovic   CURRENT DRUG TARGETS

Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181

(2010) Gallen B. Triana-Baltzer et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Targeting pandemic influenza: a primer on influenza antivirals and drug resistance

(2010) R. B. Moss et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pharmacokinetics of oseltamivir: an oral antiviral for the treatment and prophylaxis of influenza in diverse populations

(2010) B. E. Davies   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Influenza Hemagglutinin and Neuraminidase Membrane Glycoproteins

(2010) Steven J. Gamblin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner

(2010) M. P. Walkiewicz et al.   JOURNAL OF GENERAL VIROLOGY

Generation and Characterization of Recombinant Pandemic Influenza A(H1N1) Viruses Resistant to Neuraminidase Inhibitors

(2010) Andrés Pizzorno et al.   JOURNAL OF INFECTIOUS DISEASES

Attaching Zanamivir to a Polymer Markedly Enhances Its Activity Against Drug-resistant Strains of Influenza a Virus

(2010) Alisha K. Weight et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Novel Type II Transmembrane Serine Proteases, MSPL and TMPRSS13, Proteolytically Activate Membrane Fusion Activity of the Hemagglutinin of Highly Pathogenic Avian Influenza Viruses and Induce Their Multicycle Replication

(2010) Y. Okumura et al.   JOURNAL OF VIROLOGY

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

Identification of influenza A nucleoprotein as an antiviral target

(2010) Richard Y Kao et al.   NATURE BIOTECHNOLOGY

Structures of influenza A proteins and insights into antiviral drug targets

(2010) Kalyan Das et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity

(2010) C.-Y. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication

(2010) Priya Ranjan et al.   Virology Journal

Treatment of respiratory syncytial virus with palivizumab: a systematic review

(2010) Jia Hu et al.   World Journal of Pediatrics

Protection from the 2009 H1N1 Pandemic Influenza by an Antibody from Combinatorial Survivor-Based Libraries

(2010) Arun K. Kashyap et al.   PLoS Pathogens

CS-8958, a Prodrug of the Novel Neuraminidase Inhibitor R-125489, Demonstrates a Favorable Long-Retention Profile in the Mouse Respiratory Tract

(2009) K. Koyama et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice

(2009) D. F. Smee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Large-Scale Sequence Analysis of M Gene of Influenza A Viruses from Different Species: Mechanisms for Emergence and Spread of Amantadine Resistance

(2009) Y. Furuse et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

(2009) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Autophagy is involved in influenza A virus replication

(2009) Zhi Zhou et al.   Autophagy

N-acetyl-l-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus

(2009) Janina Geiler et al.   BIOCHEMICAL PHARMACOLOGY

Design and Pharmacological Characterization of Inhibitors of Amantadine-Resistant Mutants of the M2 Ion Channel of Influenza A Virus

(2009) Victoria Balannik et al.   BIOCHEMISTRY

A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection

(2009) Sagi D. Shapira et al.   CELL

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

(2009) Michaela Ulrike Gack et al.   Cell Host & Microbe

Structural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymerase

(2009) Kanako Sugiyama et al.   EMBO JOURNAL

Thiazolides, a New Class of Anti-influenza Molecules Targeting Viral Hemagglutinin at the Post-translational Level

(2009) Jean François Rossignol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bcl-2 Expression and p38MAPK Activity in Cells Infected with Influenza A Virus

(2009) Lucia Nencioni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High prevalence of amantadine resistance among circulating European porcine influenza A viruses

(2009) A. Krumbholz et al.   JOURNAL OF GENERAL VIROLOGY

Potent Inhibitors of Furin and Furin-like Proprotein Convertases Containing Decarboxylated P1 Arginine Mimetics

(2009) Gero L. Becker et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Complicated Message: Identification of a Novel PB1-Related Protein Translated from Influenza A Virus Segment 2 mRNA

(2009) H. M. Wise et al.   JOURNAL OF VIROLOGY

Detection and Characterization of Influenza A Virus PA-PB2 Interaction through a Bimolecular Fluorescence Complementation Assay

(2009) J. N. Hemerka et al.   JOURNAL OF VIROLOGY

Crystal structure of an avian influenza polymerase PAN reveals an endonuclease active site

(2009) Puwei Yuan et al.   NATURE

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

(2009) Alexandre Dias et al.   NATURE

Human host factors required for influenza virus replication

(2009) Renate König et al.   NATURE

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

(2009) Jianhua Sui et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inhibition of Neuraminidase Inhibitor-Resistant Influenza Virus by DAS181, a Novel Sialidase Fusion Protein

(2009) Gallen B. Triana-Baltzer et al.   PLoS One

Identification of a PA-Binding Peptide with Inhibitory Activity against Influenza A and B Virus Replication

(2009) Kerstin Wunderlich et al.   PLoS One

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition

(2009) Eva Böttcher et al.   VACCINE

Cross-Protective Potential of a Novel Monoclonal Antibody Directed against Antigenic Site B of the Hemagglutinin of Influenza A Viruses

(2009) Reiko Yoshida et al.   PLoS Pathogens

Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N

(2008) D SMEE et al.   ANTIVIRAL RESEARCH

Characteristics of arbidol-resistant mutants of influenza virus: Implications for the mechanism of anti-influenza action of arbidol

(2008) Irina A. Leneva et al.   ANTIVIRAL RESEARCH

Arbidol: A Broad-Spectrum Antiviral Compound that Blocks Viral Fusion

(2008) Y. Boriskin et al.   CURRENT MEDICINAL CHEMISTRY

Comment on: Concerns of using sialidase fusion protein as an experimental drug to combat seasonal and pandemic influenza

(2008) J. M. Nicholls et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Hyperinduction of Cyclooxygenase‐2–Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection

(2008) Suki M. Y. Lee et al.   JOURNAL OF INFECTIOUS DISEASES

Novel Influenza Virus NS1 Antagonists Block Replication and Restore Innate Immune Function

(2008) D. Basu et al.   JOURNAL OF VIROLOGY

Crystal structure of the polymerase PAC–PB1N complex from an avian influenza H5N1 virus

(2008) Xiaojing He et al.   NATURE

The structural basis for an essential subunit interaction in influenza virus RNA polymerase

(2008) Eiji Obayashi et al.   NATURE

Drosophila RNAi screen identifies host genes important for influenza virus replication

(2008) Linhui Hao et al.   NATURE

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells

(2008) Mark Throsby et al.   PLoS One

Analysis of the interaction of influenza virus polymerase complex with human cell factors

(2008) Núria Jorba et al.   PROTEOMICS

Host factors for replication and transcription of the influenza virus genome

(2008) Kyosuke Nagata et al.   REVIEWS IN MEDICAL VIROLOGY

Hsp90 inhibitors reduce influenza virus replication in cell culture

(2008) Geoffrey Chase et al.   VIROLOGY