Inflammation and immune system interactions in atherosclerosis

Plasmacytoid Dendritic Cells Play a Key Role in Promoting Atherosclerosis in Apolipoprotein E–Deficient Mice

(2012) Neil MacRitchie et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholesterol Efflux

(2012) Alan R. Tall et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis

(2012) Yvonne Döring et al.   CIRCULATION

The IL-17A/IL-17RA Axis Plays a Proatherogenic Role via the Regulation of Aortic Myeloid Cell Recruitment

(2012) Matthew J. Butcher et al.   CIRCULATION RESEARCH

Lymphocytes and the Adventitial Immune Response in Atherosclerosis

(2012) Kirsti A. Campbell et al.   CIRCULATION RESEARCH

Lack of Neutrophil-Derived CRAMP Reduces Atherosclerosis in Mice

(2012) Yvonne Döring et al.   CIRCULATION RESEARCH

Multiple Roles for Neutrophils in Atherosclerosis

(2012) Oliver Soehnlein   CIRCULATION RESEARCH

Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

(2012) Larissa Cardilo-Reis et al.   EMBO Molecular Medicine

Role of macrophage scavenger receptors in atherosclerosis

(2012) Julia Kzhyshkowska et al.   IMMUNOBIOLOGY

Endoplasmic Reticulum Stress Controls M2 Macrophage Differentiation and Foam Cell Formation

(2012) Jisu Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

(2012) Tin Kyaw et al.   PLoS One

Unique Proteomic Signatures Distinguish Macrophages and Dendritic Cells

(2012) Lev Becker et al.   PLoS One

Touch of Chemokines

(2012) Xavier Blanchet et al.   Frontiers in Immunology

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of Th17/Th1 and Th1, but not Th17, is associated with the acute cardiac event in patients with acute coronary syndrome

(2011) Zhao Zhao et al.   ATHEROSCLEROSIS

SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset

(2011) A. M. Zawada et al.   BLOOD

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Intravital Microscopy on Atherosclerosis in Apolipoprotein E–Deficient Mice Establishes Microvessels as Major Entry Pathways for Leukocytes to Advanced Lesions

(2011) Einar E. Eriksson   CIRCULATION

Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques

(2011) Jonathan E. Feig et al.   CIRCULATION

Immunotherapy With Tolerogenic Apolipoprotein B-100–Loaded Dendritic Cells Attenuates Atherosclerosis in Hypercholesterolemic Mice

(2011) Andreas Hermansson et al.   CIRCULATION

Extramedullary Hematopoiesis Generates Ly-6C high Monocytes That Infiltrate Atherosclerotic Lesions

(2011) Clinton S. Robbins et al.   CIRCULATION

Plasmacytoid Dendritic Cells Protect Against Atherosclerosis by Tuning T-Cell Proliferation and Activity

(2011) Isabelle T.M.N. Daissormont et al.   CIRCULATION RESEARCH

Human Atherosclerotic Plaque Alternative Macrophages Display Low Cholesterol Handling but High Phagocytosis Because of Distinct Activities of the PPARγ and LXRα Pathways

(2011) Giulia Chinetti-Gbaguidi et al.   CIRCULATION RESEARCH

Toll-like receptors and macrophage activation in atherosclerosis

(2011) Anusha N. Seneviratne et al.   CLINICA CHIMICA ACTA

Current understanding of the role of B cell subsets and intimal and adventitial B cells in atherosclerosis

(2011) Tin Kyaw et al.   CURRENT OPINION IN LIPIDOLOGY

Chemokines: established and novel targets in atherosclerosis

(2011) Rory R. Koenen et al.   EMBO Molecular Medicine

Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis

(2011) Jae-Hoon Choi et al.   IMMUNITY

CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice

(2011) Christian Weber et al.   JOURNAL OF CLINICAL INVESTIGATION

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

(2011) Andrew J. Murphy et al.   JOURNAL OF CLINICAL INVESTIGATION

Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis

(2011) Saskia C.A. de Jager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Shear Stress Induces the Release of an Endothelial Elastase: Role in Integrin αvβ3-Mediated FGF-2 Release

(2011) Theres Hennig et al.   JOURNAL OF VASCULAR RESEARCH

Adaptive immunity in atherosclerosis: mechanisms and future therapeutic targets

(2011) Charlotte Lahoute et al.   Nature Reviews Cardiology

The ABC transporters in lipid flux and atherosclerosis

(2011) Iryna Voloshyna et al.   PROGRESS IN LIPID RESEARCH

Pathogens and atherosclerosis: Update on the potential contribution of multiple infectious organisms to the pathogenesis of atherosclerosis

(2011) Lee Ann Campbell et al.   THROMBOSIS AND HAEMOSTASIS

Co-stimulatory molecules in and beyond co-stimulation – tipping the balance in atherosclerosis?

(2011) Norbert Gerdes et al.   THROMBOSIS AND HAEMOSTASIS

Platelets in atherosclerosis

(2011) Philipp von Hundelshausen et al.   THROMBOSIS AND HAEMOSTASIS

Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation

(2011) Ine Wolfs et al.   THROMBOSIS AND HAEMOSTASIS

How dendritic cells shape atherosclerosis

(2011) Ekaterina K Koltsova et al.   TRENDS IN IMMUNOLOGY

Distinct Infiltration of Neutrophils in Lesion Shoulders in ApoE−/− Mice

(2010) Pierre Rotzius et al.   AMERICAN JOURNAL OF PATHOLOGY

High Neutrophil Numbers in Human Carotid Atherosclerotic Plaques Are Associated With Characteristics of Rupture-Prone Lesions

(2010) Mihaela G. Ionita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Endoplasmic Reticulum Stress-C/EBP Homologous Protein Pathway-Mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques

(2010) Hiroto Tsukano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage-Mediated Proteolytic Remodeling of the Extracellular Matrix in Atherosclerosis Results in Neoepitopes: A Potential New Class of Biochemical Markers

(2010) Helene Skjøt-Arkil et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability

(2010) Christian Erbel et al.   BASIC RESEARCH IN CARDIOLOGY

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

(2010) D. Lievens et al.   BLOOD

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice

(2010) Daniel Kolbus et al.   BMC IMMUNOLOGY

Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

(2010) Pieter Goossens et al.   Cell Metabolism

Deficiency of Antigen-Presenting Cell Invariant Chain Reduces Atherosclerosis in Mice

(2010) Jiusong Sun et al.   CIRCULATION

Blockade of Interleukin-17A Results in Reduced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Emily Smith et al.   CIRCULATION

Hyperlipidemia-Triggered Neutrophilia Promotes Early Atherosclerosis

(2010) Maik Drechsler et al.   CIRCULATION

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

(2010) Ira Tabas   CIRCULATION RESEARCH

Changes in blood dendritic cell counts in relation to type of coronary artery disease and brachial endothelial cell function

(2010) Emily A. Van Vré et al.   CORONARY ARTERY DISEASE

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

(2010) Esther Lutgens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis

(2010) Andreas Hermansson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B cell depletion reduces the development of atherosclerosis in mice

(2010) Hafid Ait-Oufella et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conventional B2 B Cell Depletion Ameliorates whereas Its Adoptive Transfer Aggravates Atherosclerosis

(2010) T. Kyaw et al.   JOURNAL OF IMMUNOLOGY

CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

(2010) C. A. Gleissner et al.   JOURNAL OF IMMUNOLOGY

A Critical Function of Th17 Proinflammatory Cells in the Development of Atherosclerotic Plaque in Mice

(2010) Q. Gao et al.   JOURNAL OF IMMUNOLOGY

Natural Killer T Cells and Atherosclerosis: Form and Function Meet Pathogenesis

(2010) Nicole A. Braun et al.   Journal of Innate Immunity

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Monocytes in atherosclerosis: subsets and functions

(2010) Kevin J. Woollard et al.   Nature Reviews Cardiology

Macrophage Plasticity in Experimental Atherosclerosis

(2010) Jamila Khallou-Laschet et al.   PLoS One

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

(2010) L. Yvan-Charvet et al.   SCIENCE

Th17 cells, Jobʼs syndrome and HIV: opportunities for bacterial and fungal infections

(2010) Joshua D Milner et al.   Current Opinion in HIV and AIDS

Immune and Inflammatory Mechanisms of Atherosclerosis

(2009) Elena Galkina et al.   Annual Review of Immunology

NKT Cell Subsets Mediate Differential Proatherogenic Effects in ApoE −/− Mice

(2009) Kelly To et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of the Migration and Survival of Monocyte Subsets by Chemokine Receptors and Its Relevance to Atherosclerosis

(2009) Emmanuel L. Gautier et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of Schistosoma mansoni worms and eggs on circulating cholesterol and liver lipids in mice

(2009) Ronald G. Stanley et al.   ATHEROSCLEROSIS

CCR2 receptor blockade alters blood monocyte subpopulations but does not affect atherosclerotic lesions in apoE−/− mice

(2009) Robert J. Aiello et al.   ATHEROSCLEROSIS

Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe−/− mice

(2009) Charlotta Hjerpe et al.   ATHEROSCLEROSIS

The therapeutic potential of targeting B cells and anti-oxLDL antibodies in atherosclerosis

(2009) M. van Leeuwen et al.   AUTOIMMUNITY REVIEWS

Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice

(2009) T. van Es et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice

(2009) Kim L.L. Habets et al.   CARDIOVASCULAR RESEARCH

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

Heterogeneity and plasticity of T helper cells

(2009) Jinfang Zhu et al.   CELL RESEARCH

Conventional Dendritic Cells at the Crossroads Between Immunity and Cholesterol Homeostasis in Atherosclerosis

(2009) Emmanuel L. Gautier et al.   CIRCULATION

Immunoglobulin M Is Required for Protection Against Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Myles J. Lewis et al.   CIRCULATION

Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes

(2009) Alan R. Collins et al.   CIRCULATION RESEARCH

Resident Intimal Dendritic Cells Accumulate Lipid and Contribute to the Initiation of Atherosclerosis

(2009) Kim E. Paulson et al.   CIRCULATION RESEARCH

Dendritic cells in atherosclerotic disease

(2009) Alexander Niessner et al.   CLINICAL IMMUNOLOGY

Adaptive immunity and atherosclerosis

(2009) John Andersson et al.   CLINICAL IMMUNOLOGY

Macrophage heterogeneity in atherosclerotic plaques

(2009) Jason L Johnson et al.   CURRENT OPINION IN LIPIDOLOGY

The Th17/Treg functional imbalance during atherogenesis in ApoE−/− mice

(2009) Jiang-jiao Xie et al.   CYTOKINE

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves

(2009) Jae-Hoon Choi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions

(2009) Su-Ning Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

(2009) Soraya Taleb et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of IL-17A Attenuates Atherosclerotic Lesion Development in ApoE-Deficient Mice

(2009) C. Erbel et al.   JOURNAL OF IMMUNOLOGY

Monocyte Diversity in Myocardial Infarction⁎⁎Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

(2009) Eduard Shantsila et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Monocyte-Endothelial Cell Interactions in the Development of Atherosclerosis

(2009) Javier Mestas et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Loss of SR-A and CD36 Activity Reduces Atherosclerotic Lesion Complexity Without Abrogating Foam Cell Formation in Hyperlipidemic Mice

(2008) Jennifer J. Manning-Tobin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ApoE−/−/Lysozyme MEGFP/EGFP mice as a versatile model to study monocyte and neutrophil trafficking in atherosclerosis

(2008) Pierre Rotzius et al.   ATHEROSCLEROSIS

The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling

(2008) M. M. P. C. Donners et al.   BLOOD

Deficiency of invariant Vα14 natural killer T cells decreases atherosclerosis in LDL receptor null mice

(2008) Leah Rogers et al.   CARDIOVASCULAR RESEARCH

HDL, ABC Transporters, and Cholesterol Efflux: Implications for the Treatment of Atherosclerosis

(2008) Alan R. Tall et al.   Cell Metabolism

Signal Transducer and Activator of Transcription-1 Is Critical for Apoptosis in Macrophages Subjected to Endoplasmic Reticulum Stress In Vitro and in Advanced Atherosclerotic Lesions In Vivo

(2008) Wah-Seng Lim et al.   CIRCULATION

Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice

(2008) Christophe Combadière et al.   CIRCULATION

CD137 Is Expressed in Human Atherosclerosis and Promotes Development of Plaque Inflammation in Hypercholesterolemic Mice

(2008) Peder S. Olofsson et al.   CIRCULATION

CD11c + Dendritic Cells Maintain Antigen Processing, Presentation Capabilities, and CD4 + T-Cell Priming Efficacy Under Hypercholesterolemic Conditions Associated With Atherosclerosis

(2008) René R.S. Packard et al.   CIRCULATION RESEARCH

Macrophages Generate Reactive Oxygen Species in Response to Minimally Oxidized Low-Density Lipoprotein

(2008) Yun Soo Bae et al.   CIRCULATION RESEARCH

Interferon gamma: A master regulator of atherosclerosis

(2008) James E. McLaren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Requirements for CD8 T-cell migration into the human arterial wall

(2008) Jan Gewaltig et al.   HUMAN PATHOLOGY

IL-33 reduces the development of atherosclerosis

(2008) Ashley M. Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CX 3 CR1 Deficiency Impairs Dendritic Cell Accumulation in Arterial Intima and Reduces Atherosclerotic Burden

(2007) Peng Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice

(2007) Marcella van Leeuwen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fractalkine Deficiency Markedly Reduces Macrophage Accumulation and Atherosclerotic Lesion Formation in CCR2 −/− Mice

(2007) Noah Saederup et al.   CIRCULATION

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark