Protease-activated-receptor-2 affects protease-activated-receptor-1-driven breast cancer

Transactivation of the PAR1-PAR2 Heterodimer by Thrombin Elicits β-Arrestin-mediated Endosomal Signaling

(2013) Huilan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the human κ-opioid receptor in complex with JDTic

(2012) Huixian Wu et al.   NATURE

Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

(2011) Eric Reiter et al.   Annual Review of Pharmacology and Toxicology

We Can Do It Together: PAR1/PAR2 Heterodimer Signaling in VSMCs

(2011) Rafal Pawlinski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Protease-Activated Receptor-2 Modulates Protease-Activated Receptor-1–Driven Neointimal Hyperplasia

(2011) Leila M. Sevigny et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development

(2010) F. Schaffner et al.   BLOOD

Protease-activated Receptor-1 (PAR1) Acts via a Novel Gα13-Dishevelled Axis to Stabilize β-Catenin Levels

(2010) Hagit Turm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Selectivity and Biased Receptor Signaling

(2010) T. Kenakin   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

PAR1 and PAR2 Couple to Overlapping and Distinct Sets of G Proteins and Linked Signaling Pathways to Differentially Regulate Cell Physiology

(2010) K. L. McCoy et al.   MOLECULAR PHARMACOLOGY

Etk/Bmx Regulates Proteinase-Activated-Receptor1 (PAR1) in Breast Cancer Invasion: Signaling Partners, Hierarchy and Physiological Significance

(2010) Irit Cohen et al.   PLoS One

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

Dimerization in GPCR mobility and signaling

(2009) Martin J Lohse   CURRENT OPINION IN PHARMACOLOGY

Protease-Activated Receptor (PAR) 2, but not PAR1, Signaling Promotes the Development of Mammary Adenocarcinoma in Polyoma Middle T Mice

(2008) H. H. Versteeg et al.   CANCER RESEARCH

Slamming the DOR on chemokine receptor signaling: Heterodimerization silences ligand-occupied CXCR4 and δ-opioid receptors

(2008) Dale Hereld et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Protease activated receptor-1, PAR1, promotes placenta trophoblast invasion and β-catenin stabilization

(2008) Sorina Grisaru-Granovsky et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

(2008) Michael A. Hanson et al.   STRUCTURE