NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity

Antibody-Mediated Inhibition of Integrin α5β1 Blocks Neurotoxic Prion Peptide PrP106–126-Induced Activation of BV2 Microglia

(2012) Jiaxin Chang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

(2012) Fushan Shi et al.   Journal of Neuroinflammation

Introduction of glutamines into the B2–H2 loop promotes prion protein conversion

(2011) Matevž Avbelj et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Globular Domain of the Prion Protein Needs to Be Unlocked by Domain Swapping to Support Prion Protein Conversion

(2011) Iva Hafner-Bratkovič et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

(2011) K. Niemi et al.   JOURNAL OF IMMUNOLOGY

Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo

(2011) Iva Hafner-Bratkovič et al.   PLoS One

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

(2010) Natallia Makarava et al.   ACTA NEUROPATHOLOGICA

Tetracysteine-tagged prion protein allows discrimination between the native and converted forms

(2010) Jernej Gašperšič et al.   FEBS Journal

Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

(2010) Jae-Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

(2010) M. Ritter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

The Physical Relationship between Infectivity and Prion Protein Aggregates Is Strain-Dependent

(2010) Philippe Tixador et al.   PLoS Pathogens

Analysis of Protein Levels of 24 Cytokines in Scrapie Agent-Infected Brain and Glial Cell Cultures from Mice Differing in Prion Protein Expression Levels

(2009) D. Tribouillard-Tanvier et al.   JOURNAL OF VIROLOGY

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genes contributing to prion pathogenesis

(2008) G. Tamguney et al.   JOURNAL OF GENERAL VIROLOGY

Accelerated Prion Disease Pathogenesis in Toll-Like Receptor 4 Signaling-Mutant Mice

(2008) D. S. Spinner et al.   JOURNAL OF VIROLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE