标题
Polyreactive antibodies in adaptive immune responses to viruses
作者
关键词
-
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 69, Issue 9, Pages 1435-1445
出版商
Springer Nature
发表日期
2011-11-02
DOI
10.1007/s00018-011-0872-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Reactivity profiles of broadly neutralizing anti-HIV-1 antibodies are distinct from those of pathogenic autoantibodies
- (2011) Harvir Singh et al. AIDS
- The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific
- (2011) Julia Benckert et al. JOURNAL OF CLINICAL INVESTIGATION
- Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
- (2011) Jens Wrammert et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Rescue of HIV-1 Broad Neutralizing Antibody-Expressing B Cells in 2F5 VH x VL Knockin Mice Reveals Multiple Tolerance Controls
- (2011) L. Verkoczy et al. JOURNAL OF IMMUNOLOGY
- Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
- (2011) M. Bonsignori et al. JOURNAL OF VIROLOGY
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Inflammation-independent defective early B cell tolerance checkpoints in rheumatoid arthritis
- (2010) Laurence Menard et al. ARTHRITIS AND RHEUMATISM
- The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity
- (2010) Martina Beltramello et al. Cell Host & Microbe
- Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity
- (2010) Wenzhong Guo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Nonneutralizing HIV-1 gp41 Envelope Cluster II Human Monoclonal Antibodies Show Polyreactivity for Binding to Phospholipids and Protein Autoantigens
- (2010) S. M. Dennison et al. JOURNAL OF VIROLOGY
- Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization
- (2010) J. M. Binley et al. JOURNAL OF VIROLOGY
- Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
- (2010) Hugo Mouquet et al. NATURE
- Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity
- (2010) Ron Diskin et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Evolving concepts of specificity in immune reactions
- (2010) H. N. Eisen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions
- (2010) E. M. Scherer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- Cross-Reacting Antibodies Enhance Dengue Virus Infection in Humans
- (2010) W. Dejnirattisai et al. SCIENCE
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- Isolation of Human Monoclonal Antibodies That Potently Neutralize Human Cytomegalovirus Infection by Targeting Different Epitopes on the gH/gL/UL128-131A Complex
- (2009) A. Macagno et al. JOURNAL OF VIROLOGY
- Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
- (2009) Johannes F. Scheid et al. NATURE
- Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10
- (2009) J. S. Klein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of HIV membrane in neutralization by two broadly neutralizing antibodies
- (2009) S. M. Alam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
- (2009) L. Verkoczy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Variants of the Antibody Herceptin That Interact with HER2 and VEGF at the Antigen Binding Site
- (2009) J. Bostrom et al. SCIENCE
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
- EBV in MS: guilty by association?
- (2009) Jan D. Lünemann et al. TRENDS IN IMMUNOLOGY
- Challenges for structure-based HIV vaccine design
- (2009) William R Schief et al. Current Opinion in HIV and AIDS
- Regulation and dysregulation of Epstein–Barr virus latency: Implications for the development of autoimmune diseases
- (2008) Hans Helmut Niller et al. AUTOIMMUNITY
- Lipid binding properties of 4E10, 2F5, and WR304 monoclonal antibodies that neutralize HIV-1
- (2008) Gary R. Matyas et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- B-cell tolerance checkpoints in health and autoimmunity
- (2008) Eric Meffre et al. CURRENT OPINION IN IMMUNOLOGY
- Lipid modulation of membrane-bound epitope recognition and blocking by HIV-1 neutralizing antibodies
- (2008) Nerea Huarte et al. FEBS LETTERS
- IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans
- (2008) Isabelle Isnardi et al. IMMUNITY
- HIV-1 Broadly Neutralizing Antibody Extracts Its Epitope from a Kinked gp41 Ectodomain Region on the Viral Membrane
- (2008) Zhen-Yu J. Sun et al. IMMUNITY
- EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-γ and IL-2
- (2008) Jan D. Lünemann et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 4E10 Monoclonal Antibody Is Better Adapted to Membrane-Bound Epitope Recognition and Blocking than 2F5
- (2008) N. Huarte et al. JOURNAL OF VIROLOGY
- Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
- (2008) Jens Wrammert et al. NATURE
- Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors
- (2008) B. Mietzner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
- (2008) G. Frey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Antibody Paratope Conformational Flexibility in the Manifestation of Molecular Mimicry
- (2007) Lavanya Krishnan et al. BIOPHYSICAL JOURNAL
- The specificity of cross-reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness
- (2003) Leo C. James et al. PROTEIN SCIENCE
- Multiple diverse ligands binding at a single protein site: A matter of pre-existing populations
- (2002) Buyong Ma et al. PROTEIN SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started