Cyclic AMP: a selective modulator of NF-κB action

Morphine Withdrawal Inhibits IL-12 Induction in a Macrophage Cell Line through a Mechanism That Involves cAMP

(2014) J. Kelschenbach et al.   JOURNAL OF IMMUNOLOGY

Anti-Inflammatory Role of Cilostazol in Vascular Smooth Muscle Cells In vitro and In vivo

(2011) Chie Aoki et al.   Journal of Atherosclerosis and Thrombosis

Hyperactivation of NF-κB via the MEK signaling is indispensable for the inhibitory effect of cAMP on DNA damage-induced cell death

(2011) Martine M Kloster et al.   Molecular Cancer

Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-κB activation

(2010) Pu Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction

(2010) So Youn Park et al.   ARTHRITIS AND RHEUMATISM

Enhancement of inflammatory mediator release by β2-adrenoceptor agonists in airway epithelial cells is reversed by glucocorticoid action

(2010) NS Holden et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cooperation of NFκB and CREB to induce synergistic IL-6 expression in astrocytes

(2010) Anneleen Spooren et al.   CELLULAR SIGNALLING

Elevation of cyclic AMP causes an imbalance between NF-κB and p53 in NALM-6 cells treated by doxorubicin

(2010) Majid Safa et al.   FEBS LETTERS

Constitutively active NF- B triggers systemic TNF -dependent inflammation and localized TNF -independent inflammatory disease

(2010) J. Dong et al.   GENES & DEVELOPMENT

Olprinone attenuates the development of ischemia/reperfusion injury of the gut

(2010) Concetta Crisafulli et al.   INTENSIVE CARE MEDICINE

A-kinase-interacting Protein 1 (AKIP1) Acts as a Molecular Determinant of PKA in NF-κB Signaling

(2010) Nan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombin and Collagen Induce a Feedback Inhibitory Signaling Pathway in Platelets Involving Dissociation of the Catalytic Subunit of Protein Kinase A from an NFκB-IκB Complex

(2010) Stepan Gambaryan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hunting for Serine 276-Phosphorylated p65

(2010) Anneleen Spooren et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Modulation of Cytokine Production by Cyclic Adenosine Monophosphate Analogs in Human Leukocytes

(2010) Sarah Gerlo et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-κB-independent manner

(2010) Lirlândia P. Sousa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

EFFECT OF OLPRINONE, A PHOSPHODIESTERASE III INHIBITOR, ON HEPATIC ISCHEMIA-REPERFUSION INJURY IN RATS

(2010) Keisuke Yamaguchi et al.   SHOCK

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-κB

(2009) Lirlândia P. Sousa et al.   BIOCHEMICAL PHARMACOLOGY

Identification of a small molecule inhibitor of serine 276 phosphorylation of the p65 subunit of NF-κB using in silico molecular docking

(2009) Mary Law et al.   CANCER LETTERS

Elevation of intracellular cyclic AMP inhibits NF-κB-mediated thymosin β4 expression in melanoma cells

(2009) Aeyung Kim et al.   EXPERIMENTAL CELL RESEARCH

Cyclic Adenosine Monophosphate Suppresses the Transcription of Proinflammatory Cytokines via the Phosphorylated c-Fos Protein

(2009) Keiko Koga et al.   IMMUNITY

Cyclic AMP Inhibits IL-1β Plus IFNγ-Induced NF-κB Translocation in Hepatocytes by a PKA Independent Mechanism

(2009) Guiying Hong et al.   JOURNAL OF SURGICAL RESEARCH

The adenylyl cyclase-cAMP system suppresses TARC/CCL17 and MDC/CCL22 production through p38 MAPK and NF-κB in HaCaT keratinocytes

(2009) Xu-Feng Qi et al.   MOLECULAR IMMUNOLOGY

Adenylyl Cyclase-A-kinase Anchoring Protein Complexes: The Next Dimension in cAMP Signaling

(2009) C. W. Dessauer   MOLECULAR PHARMACOLOGY

Constitutive Expression of MC1R in HaCaT Keratinocytes Inhibits Basal and UVB-induced TNF-α Production

(2009) Geneviève Garcin et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Suppression of LPS-Induced TNF-  Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105

(2009) E. A. Wall et al.   Science Signaling

Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease

(2008) Leila Gobejishvili et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effect of β2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A

(2008) Manminder Kaur et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cyclic AMP

(2008) Carlos H. Serezani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Gq-dependent signalling by the lysophosphatidic acid receptor LPA3in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA

(2008) Wimolpak Sriwai et al.   BIOCHEMICAL JOURNAL

Synergistic induction of nuclear factor-κB by transforming growth factor-β and tumour necrosis factor-α is mediated by protein kinase A-dependent RelA acetylation

(2008) Hajime Ishinaga et al.   BIOCHEMICAL JOURNAL

Identification of genes, including the gene encoding p27Kip1, regulated by serine 276 phosphorylation of the p65 subunit of NF-κB

(2008) Ratna Chakraborty Prasad et al.   CANCER LETTERS

Insights into the regulation of TNF-a production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition

(2008) Jessica Deree et al.   Clinics

Repression of gene expression by unphosphorylated NF- B p65 through epigenetic mechanisms

(2008) J. Dong et al.   GENES & DEVELOPMENT

G Protein–Coupled Receptor Connectivity to NF-κB in Inflammation and Cancer

(2008) Christopher C. Fraser   INTERNATIONAL REVIEWS OF IMMUNOLOGY

AKIP1 Enhances NF-κB-dependent Gene Expression by Promoting the Nuclear Retention and Phosphorylation of p65

(2008) Nan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenylate cycalse toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells

(2008) Fionnuala B. Hickey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Protein Kinase A-Induced Phosphorylation of the p65 Subunit of Nuclear Factor- B Promotes Schwann Cell Differentiation into a Myelinating Phenotype

(2008) C. Yoon et al.   JOURNAL OF NEUROSCIENCE

Inhibition of 5‐HT1Areceptor‐dependent cell survival by cAMP/protein kinase A: Role of protein phosphatase 2A and Bax

(2008) Shu‐chi Hsiung et al.   JOURNAL OF NEUROSCIENCE RESEARCH

RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF- B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes

(2008) D. E. Nowak et al.   MOLECULAR AND CELLULAR BIOLOGY

Pharmacological PKA Inhibition: All May Not Be What It Seems

(2008) A. J. Murray   Science Signaling