The shrimp IKK–NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral gene expression

Litopenaeus vannamei Toll-interacting protein (LvTollip) is a potential negative regulator of the shrimp Toll pathway involved in the regulation of the shrimp antimicrobial peptide gene penaeidin-4 (PEN4)

(2013) Pei-Hui Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Litopenaeus vannamei Sterile-Alpha and Armadillo Motif Containing Protein (LvSARM) Is Involved in Regulation of Penaeidins and antilipopolysaccharide factors

(2013) Pei-Hui Wang et al.   PLoS One

Identification, Characterization, and Function Analysis of the Cactus Gene from Litopenaeus vannamei

(2012) Chaozheng Li et al.   PLoS One

Identification and Function of Myeloid Differentiation Factor 88 (MyD88) in Litopenaeus vannamei

(2012) Shuang Zhang et al.   PLoS One

Molecular cloning, characterization and expression analysis of two novel Tolls (LvToll2 and LvToll3) and three putative Spätzle-like Toll ligands (LvSpz1–3) from Litopenaeus vannamei

(2011) Pei-Hui Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular cloning, characterization and expression analysis of the tumor necrosis factor (TNF) superfamily gene, TNF receptor superfamily gene and lipopolysaccharide-induced TNF-α factor (LITAF) gene from Litopenaeus vannamei

(2011) Pei-Hui Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The Drosophila Toll Signaling Pathway

(2011) S. Valanne et al.   JOURNAL OF IMMUNOLOGY

The Shrimp NF-κB Pathway Is Activated by White Spot Syndrome Virus (WSSV) 449 to Facilitate the Expression of WSSV069 (ie1), WSSV303 and WSSV371

(2011) Pei-Hui Wang et al.   PLoS One

NF-κB Hyper-Activation by HTLV-1 Tax Induces Cellular Senescence, but Can Be Alleviated by the Viral Anti-Sense Protein HBZ

(2011) Huijun Zhi et al.   PLoS Pathogens

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Innate antiviral immunity in Drosophila

(2010) Leah R Sabin et al.   CURRENT OPINION IN IMMUNOLOGY

A Dorsal homolog (FcDorsal) in the Chinese shrimp Fenneropenaeus chinensis is responsive to both bacteria and WSSV challenge

(2010) Fuhua Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Litopenaeus vannamei tumor necrosis factor receptor-associated factor 6 (TRAF6) responds to Vibrio alginolyticus and white spot syndrome virus (WSSV) infection and activates antimicrobial peptide genes

(2010) Pei-Hui Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Shrimp NF-κB binds to the immediate-early gene ie1 promoter of white spot syndrome virus and upregulates its activity

(2010) Xian-De Huang et al.   VIROLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pathogen recognition in the innate immune response

(2009) Himanshu Kumar et al.   BIOCHEMICAL JOURNAL

Antiviral immunity in drosophila

(2009) Cordula Kemp et al.   CURRENT OPINION IN IMMUNOLOGY

Identification of a novel relish homolog in Chinese shrimp Fenneropenaeus chinensis and its function in regulating the transcription of antimicrobial peptides

(2009) Fuhua Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Identification and functional study of a shrimp Dorsal homologue

(2009) Xian-De Huang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Cloning of penaeidin gene promoter in tiger shrimp (Penaeus monodon)

(2009) Shih-Hu Ho et al.   FISH & SHELLFISH IMMUNOLOGY

Identification and functional study of a shrimp Relish homologue

(2009) Xian-De Huang et al.   FISH & SHELLFISH IMMUNOLOGY

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

An immune deficiency homolog from the white shrimp, Litopenaeus vannamei, activates antimicrobial peptide genes

(2009) Pei-Hui Wang et al.   MOLECULAR IMMUNOLOGY

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

(2009) D. Erturk-Hasdemir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the immediate-early genes of white spot syndrome virus

(2009) Fang Li et al.   VIROLOGY

The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis

(2008) Dikla Dubin-Bar et al.   BMC CELL BIOLOGY

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS

Transactivation, Dimerization, and DNA-Binding Activity of White Spot Syndrome Virus Immediate-Early Protein IE1

(2008) W.-J. Liu et al.   JOURNAL OF VIROLOGY

A relationship between antimicrobial peptide gene expression and capacity of a selected shrimp line to survive a Vibrio infection

(2008) Julien de Lorgeril et al.   MOLECULAR IMMUNOLOGY