Molecular Mechanisms Controlling Vascular Lumen Formation in Three-Dimensional Extracellular Matrices

VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines

(2011) A. N. Stratman et al.   BLOOD

Molecular Regulation of Lumen Morphogenesis

(2011) Anirban Datta et al.   CURRENT BIOLOGY

Shedding Light on Mammalian Microautophagy

(2011) Tomer Shpilka et al.   DEVELOPMENTAL CELL

Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice

(2011) Aubrey C. Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiogenesis

(2011) D. R. Senger et al.   Cold Spring Harbor Perspectives in Biology

A Homozygous Mutation in the Tight-Junction Protein JAM3 Causes Hemorrhagic Destruction of the Brain, Subependymal Calcification, and Congenital Cataracts

(2010) Ganeshwaran H. Mochida et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization

(2010) A. N. Stratman et al.   BLOOD

Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events

(2010) A. Sacharidou et al.   BLOOD

Active Rac1 improves pathologic VEGF neovessel architecture and reduces vascular leak: mechanistic similarities with angiopoietin-1

(2010) M. V. Hoang et al.   BLOOD

Extracellular matrix, inflammation, and the angiogenic response

(2010) A. G. Arroyo et al.   CARDIOVASCULAR RESEARCH

Par3 Controls Epithelial Spindle Orientation by aPKC-Mediated Phosphorylation of Apical Pins

(2010) Yi Hao et al.   CURRENT BIOLOGY

Endothelial  5 and  v integrins cooperate in remodeling of the vasculature during development

(2010) A. van der Flier et al.   DEVELOPMENT

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

(2010) Y. Wang et al.   DEVELOPMENT

β1 Integrin Establishes Endothelial Cell Polarity and Arteriolar Lumen Formation via a Par3-Dependent Mechanism

(2010) Ann C. Zovein et al.   DEVELOPMENTAL CELL

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

(2010) M. G. Lampugnani et al.   JOURNAL OF CELL SCIENCE

CCM3 signaling through sterile 20–like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations

(2010) Xiangjian Zheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

(2010) Rebecca A. Stockton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ccm1 Regulates Microvascular Morphogenesis during Angiogenesis

(2010) Huiling Liu et al.   JOURNAL OF VASCULAR RESEARCH

The Effects of Hemodynamic Force on Embryonic Development

(2010) JAMES C. CULVER et al.   MICROCIRCULATION

Cdc42-mediated inhibition of GSK-3β improves angio-architecture and lumen formation during VEGF-driven pathological angiogenesis

(2010) Mien V. Hoang et al.   MICROVASCULAR RESEARCH

A molecular network for de novo generation of the apical surface and lumen

(2010) David M. Bryant et al.   NATURE CELL BIOLOGY

Dynamic Analysis of Vascular Morphogenesis Using Transgenic Quail Embryos

(2010) Yuki Sato et al.   PLoS One

A Key Role for the Integrin α2β1 in Experimental and Developmental Angiogenesis

(2009) James D. San Antonio et al.   AMERICAN JOURNAL OF PATHOLOGY

Fibronectins in vascular morphogenesis

(2009) Sophie Astrof et al.   ANGIOGENESIS

Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis

(2009) Konstantin Gaengel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation

(2009) A. N. Stratman et al.   BLOOD

Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices

(2009) A. N. Stratman et al.   BLOOD

PAKing up to the endothelium

(2009) Eva Maria Galan Moya et al.   CELLULAR SIGNALLING

Rasip1 is required for endothelial cell motility, angiogenesis and vessel formation

(2009) Ke Xu et al.   DEVELOPMENTAL BIOLOGY

Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration

(2009) Deborah J. Andrew et al.   DEVELOPMENTAL BIOLOGY

Cellular and Molecular Mechanisms of Vascular Lumen Formation

(2009) M. Luisa Iruela-Arispe et al.   DEVELOPMENTAL CELL

The Molecular Basis of Vascular Lumen Formation in the Developing Mouse Aorta

(2009) Boris Strilić et al.   DEVELOPMENTAL CELL

The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications

(2009) Elisabetta Dejana et al.   DEVELOPMENTAL CELL

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices

(2009) Kevin E. Fisher et al.   JOURNAL OF CELL SCIENCE

Formation of endothelial lumens requires a coordinated PKC -, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation

(2009) W. Koh et al.   JOURNAL OF CELL SCIENCE

Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation

(2009) Yanmei Tian et al.   MECHANISMS OF DEVELOPMENT

The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

(2009) Kevin J Whitehead et al.   NATURE MEDICINE

Regulation of cardiovascular development and integrity by the heart of glass–cerebral cavernous malformation protein pathway

(2009) Benjamin Kleaveland et al.   NATURE MEDICINE

Vascular Extracellular Matrix and Arterial Mechanics

(2009) Jessica E. Wagenseil et al.   PHYSIOLOGICAL REVIEWS

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Arterial-Venous Segregation by Selective Cell Sprouting: An Alternative Mode of Blood Vessel Formation

(2009) S. P. Herbert et al.   SCIENCE

Integrin and Growth Factor Receptor Alliance in Angiogenesis

(2008) Payaningal R. Somanath et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis

(2008) Matthew T. Holderfield et al.   CIRCULATION RESEARCH

Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis

(2008) Fernando Martín-Belmonte et al.   CURRENT BIOLOGY

Extracellular matrix mediates a molecular balance between vascular morphogenesis and regression

(2008) George E Davis et al.   CURRENT OPINION IN HEMATOLOGY

Endothelial???stromal interactions in angiogenesis

(2008) Christopher CW Hughes   CURRENT OPINION IN HEMATOLOGY

Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo

(2008) Yannick Blum et al.   DEVELOPMENTAL BIOLOGY

An essential role for Rac1 in endothelial cell function and vascular development

(2008) Wenfu Tan et al.   FASEB JOURNAL

Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

(2008) Aron B. Jaffe et al.   JOURNAL OF CELL BIOLOGY

Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling

(2008) W. Koh et al.   JOURNAL OF CELL SCIENCE

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY