A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neurons

FoxO3a is activated and executes neuron death via Bim in response to β-amyloid

(2013) P Sanphui et al.   Cell Death & Disease

Silencing of proviruses in embryonic cells: efficiency, stability and chromatin modifications

(2012) Sharon Schlesinger et al.   EMBO REPORTS

PI3K-independent AKT activation in cancers: A treasure trove for novel therapeutics

(2012) Kiran Mahajan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Global analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death

(2011) Mark Kristiansen et al.   BMC GENOMICS

miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis

(2011) A. J. Kole et al.   GENES & DEVELOPMENT

TRB3 interacts with SMAD3 promoting tumor cell migration and invasion

(2011) F. Hua et al.   JOURNAL OF CELL SCIENCE

TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma

(2011) Jing Zhang et al.   ORAL ONCOLOGY

TRIB3 protein denotes a good prognosis in breast cancer patients and is associated with hypoxia sensitivity

(2011) Marloes Wennemers et al.   RADIOTHERAPY AND ONCOLOGY

NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons

(2010) R Hughes et al.   CELL DEATH AND DIFFERENTIATION

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse β cells

(2010) Chong Wee Liew et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

(2009) John D. Cravero et al.   ARTHRITIS AND RHEUMATISM

Involvement of Akt in neurite outgrowth

(2009) Danielle E. Read et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Molecular Mechanism of Endoplasmic Reticulum Stress-Induced Apoptosis in PC-12 Neuronal Cells: The Protective Effect of Insulin-Like Growth Factor I

(2008) Cheng-Gang Zou et al.   ENDOCRINOLOGY

TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activity

(2008) Yu Takahashi et al.   JOURNAL OF LIPID RESEARCH