Local and global functions of Timeless and Tipin in replication fork protection

Replication fork dynamics and the DNA damage response

(2012) Rebecca M. Jones et al.   BIOCHEMICAL JOURNAL

Sister chromatid cohesion establishment occurs in concert with lagging strand synthesis

(2012) Soumya Rudra et al.   CELL CYCLE

Timeless preserves telomere length by promoting efficient DNA replication through human telomeres

(2012) Adam R. Leman et al.   CELL CYCLE

DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase

(2012) N. Sabouri et al.   GENES & DEVELOPMENT

Altered Replication in Human Cells Promotes DMPK (CTG)n {middle dot} (CAG)n Repeat Instability

(2012) G. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis

(2012) Guoqi Liu et al.   Cell and Bioscience

Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts

(2011) Stephanie L. Smith-Roe et al.   CELL CYCLE

Division of labor of the replication fork protection complex subunits in sister chromatid cohesion and Chk1 activation

(2011) Eishi Noguchi   CELL CYCLE

Timeless Links Replication Termination to Mitotic Kinase Activation

(2011) Jayaraju Dheekollu et al.   PLoS One

Warsaw Breakage Syndrome, a Cohesinopathy Associated with Mutations in the XPD Helicase Family Member DDX11/ChlR1

(2010) Petra van der Lelij et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Eukaryotic Chromosome DNA Replication: Where, When, and How?

(2010) Hisao Masai et al.   Annual Review of Biochemistry

Sister acts: coordinating DNA replication and cohesion establishment

(2010) R. Sherwood et al.   GENES & DEVELOPMENT

Identification of proteins that may directly interact with human RPA

(2010) Ryou Nakaya et al.   JOURNAL OF BIOCHEMISTRY

Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress

(2010) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

(2010) A. R. Leman et al.   JOURNAL OF CELL SCIENCE

GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome

(2010) Matthew D Sekedat et al.   Molecular Systems Biology

Damage-induced phosphorylation of Sld3 is important to block late origin firing

(2010) Jaime Lopez-Mosqueda et al.   NATURE

Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation

(2010) Philip Zegerman et al.   NATURE

Protection and replication of telomeres in fission yeastThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

(2009) Bettina A. Moser et al.   Biochemistry and Cell Biology

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

Cornelia de Lange syndrome, cohesin, and beyond

(2009) J Liu et al.   CLINICAL GENETICS

Tipin/Tim1/And1 protein complex promotes Polα chromatin binding and sister chromatid cohesion

(2009) Alessia Errico et al.   EMBO JOURNAL

A matter of choice: the establishment of sister chromatid cohesion

(2009) Frank Uhlmann   EMBO REPORTS

Replisome progression complex links DNA replication to sister chromatid cohesion inXenopusegg extracts

(2009) Hiroshi Tanaka et al.   GENES TO CELLS

Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast

(2009) Michie Shimmoto et al.   GENES TO CELLS

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

(2009) Kevin D. Smith et al.   JOURNAL OF CELL BIOLOGY

Checkpoint responses to unusual structures formed by DNA repeats

(2009) Irina Voineagu et al.   MOLECULAR CARCINOGENESIS

Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae

(2009) Anna Azvolinsky et al.   MOLECULAR CELL

Large-Scale Expansions of Friedreich's Ataxia GAA Repeats in Yeast

(2009) Alexander A. Shishkin et al.   MOLECULAR CELL

Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility

(2009) Irina Voineagu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sister Chromatid Cohesion: A Simple Concept with a Complex Reality

(2008) Itay Onn et al.   Annual Review of Cell and Developmental Biology

Welcome the Family of FANCJ-like Helicases to the Block of Genome Stability Maintenance Proteins

(2008) Y. Wu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rtf1-Mediated Eukaryotic Site-Specific Replication Termination

(2008) T. Eydmann et al.   GENETICS

Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication

(2008) Karen A. Urtishak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Studies with the Human Cohesin Establishment Factor, ChlR1

(2008) Andrea Farina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acetylation of Smc3 by Eco1 Is Required for S Phase Sister Chromatid Cohesion in Both Human and Yeast

(2008) Jinglan Zhang et al.   MOLECULAR CELL

Cohesinopathies: One ring, many obligations

(2008) Adrian J. McNairn et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS

Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins

(2008) I. Voineagu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RFCCtf18 and the Swi1-Swi3 Complex Function in Separate and Redundant Pathways Required for the Stabilization of Replication Forks to Facilitate Sister Chromatid Cohesion in Schizosaccharomyces pombe

(2007) Alison B. Ansbach et al.   MOLECULAR BIOLOGY OF THE CELL