CD39 is a negative regulator of P2X7-mediated inflammatory cell death in mast cells

P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1  in Mouse Macrophage

(2014) P. Pelegrin et al.   JOURNAL OF IMMUNOLOGY

Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin

(2013) Silvia L. Lage et al.   METHODS

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

(2013) Takuma Misawa et al.   NATURE IMMUNOLOGY

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

(2013) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

P2X7 receptor regulation of non-classical secretion from immune effector cells

(2012) George R. Dubyak   CELLULAR MICROBIOLOGY

Purinergic P2Y2 Receptors Promote Neutrophil Infiltration and Hepatocyte Death in Mice With Acute Liver Injury

(2012) Cemil Korcan Ayata et al.   GASTROENTEROLOGY

Critical Role for Mast Cells in Interleukin-1β-Driven Skin Inflammation Associated with an Activating Mutation in the Nlrp3 Protein

(2012) Yuumi Nakamura et al.   IMMUNITY

Overexpression of CD39 in Mouse Airways Promotes Bacteria-Induced Inflammation

(2012) E. Theatre et al.   JOURNAL OF IMMUNOLOGY

Activation of the PI3K pathway increases TLR-induced TNF-α and IL-6 but reduces IL-1β production in mast cells

(2011) Thomas Hochdörfer et al.   CELLULAR SIGNALLING

Understanding the mechanism of IL-1β secretion

(2011) Gloria Lopez-Castejon et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Mast Cells as Sensors of Cell Injury through IL-33 Recognition

(2011) M. Enoksson et al.   JOURNAL OF IMMUNOLOGY

NTPDase1 governs P2X7-dependent functions in murine macrophages

(2010) Sébastien A. Lévesque et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Caspase 1–independent activation of interleukin-1β in neutrophil-predominant inflammation

(2009) Monica Guma et al.   ARTHRITIS AND RHEUMATISM

Inflammatory arthritis in caspase 1 gene–deficient mice: Contribution of proteinase 3 to caspase 1–independent production of bioactive interleukin-1β

(2009) Leo A. B. Joosten et al.   ARTHRITIS AND RHEUMATISM

The P2X7 receptor–pannexin connection to dye uptake and IL-1β release

(2009) Pablo Pelegrin et al.   Purinergic Signalling

Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS-induced PMN trafficking into the lungs

(2008) Jörg Reutershan et al.   FASEB JOURNAL