Role of ELA region in auto-activation of mutant KIT receptor: a molecular dynamics simulation insight

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(2016)   JOURNAL OF COMPUTATIONAL CHEMISTRY

Investigation of Binding Phenomenon of NSP3 and p130Cas Mutants and Their Effect on Cell Signalling

(2013) Balu K. et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Relationship between a point mutation S97C in CK1δ protein and its affect on ATP-binding affinity

(2013) Ambuj Kumar et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Drug resistance mechanism of PncA inMycobacterium tuberculosis

(2013) Vidya Rajendran et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Studies on Adaptability of Binding Residues Flap Region of TMC-114 Resistance HIV-1 Protease Mutants

(2012) Rituraj Purohit et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Allosteric Communication across the Native and Mutated KIT Receptor Tyrosine Kinase

(2012) Elodie Laine et al.   PLoS Computational Biology

In silico investigation of molecular mechanism of laminopathy caused by a point mutation (R482W) in lamin A/C protein

(2011) Vidya Rajendran et al.   AMINO ACIDS

Mutation D816V Alters the Internal Structure and Dynamics of c-KIT Receptor Cytoplasmic Region: Implications for Dimerization and Activation Mechanisms

(2011) Elodie Laine et al.   PLoS Computational Biology

Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance

(2010) J. P. DiNitto et al.   JOURNAL OF BIOCHEMISTRY

Relationship between mutation of serine residue at 315th position in M. tuberculosis catalase-peroxidase enzyme and Isoniazid susceptibility: An in silico analysis

(2010) Rituraj Purohit et al.   JOURNAL OF MOLECULAR MODELING

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry

(2010) Hui-Min Zhang et al.   PROTEIN SCIENCE

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

(2009) K. S. Gajiwala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for the resilience of Darunavir (TMC114) resistance major flap mutations of HIV-1 protease

(2009) Rituraj Purohit et al.   Interdisciplinary Sciences-Computational Life Sciences

Studies on flexibility and binding affinity of Asp25 of HIV-1 protease mutants

(2008) Rituraj Purohit et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Heterogeneity of kinase inhibitor resistance mechanisms in GIST

(2008) B Liegl et al.   JOURNAL OF PATHOLOGY

Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases

(2008) Jerzy Lasota et al.   MODERN PATHOLOGY

Molecular Dynamics Simulations of Hemoglobin A in Different States and Bound to DPG: Effector-Linked Perturbation of Tertiary Conformations and HbA Concerted Dynamics

(2007) Monique Laberge et al.   BIOPHYSICAL JOURNAL