Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis

Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery DiseaseSignificance

(2015) Sujoy Ghosh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency

(2015) Christina V. Theodoris et al.   CELL

The role of oxidative stress, antioxidants and vascular inflammation in cardiovascular disease (a review)

(2015) Hawa N. Siti et al.   VASCULAR PHARMACOLOGY

Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner

(2014) Lin Wang et al.   Cell Stem Cell

Transgenic Expression of Dominant-Active IDOL in Liver Causes Diet-Induced Hypercholesterolemia and Atherosclerosis in Mice

(2014) Anna C. Calkin et al.   CIRCULATION RESEARCH

Repression of Sox9 by Jag1 Is Continuously Required to Suppress the Default Chondrogenic Fate of Vascular Smooth Muscle Cells

(2014) Anaïs Briot et al.   DEVELOPMENTAL CELL

HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms

(2014) Benjamin Emert et al.   JOURNAL OF LIPID RESEARCH

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

(2014) Saravana K. Ramasamy et al.   NATURE

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

(2014) Andreas Schober et al.   NATURE MEDICINE

Notch signal integration in the vasculature during remodeling

(2014) Bahman Rostama et al.   VASCULAR PHARMACOLOGY

Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

(2014) Ville-Petteri Mäkinen et al.   PLoS Genetics

Gene Expression Analyses of Mouse Aortic Endothelium in Response to Atherogenic Stimuli

(2013) Ayca Erbilgin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adaptive immunity in atherogenesis: new insights and therapeutic approaches

(2013) Andrew H. Lichtman et al.   JOURNAL OF CLINICAL INVESTIGATION

HLA Class I Antibodies Trigger Increased Adherence of Monocytes to Endothelial Cells by Eliciting an Increase in Endothelial P-Selectin and, Depending on Subclass, by Engaging Fc Rs

(2013) N. M. Valenzuela et al.   JOURNAL OF IMMUNOLOGY

Regulation of signal transduction by HDL

(2013) Chieko Mineo et al.   JOURNAL OF LIPID RESEARCH

High density lipoproteins and endothelial functions: mechanistic insights and alterations in cardiovascular disease

(2013) Meliana Riwanto et al.   JOURNAL OF LIPID RESEARCH

Cardioprotective functions of HDLs

(2013) Kerry-Anne Rye et al.   JOURNAL OF LIPID RESEARCH

Identification of CAD candidate genes in GWAS loci and their expression in vascular cells

(2013) Ayca Erbilgin et al.   JOURNAL OF LIPID RESEARCH

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Notch activation induces endothelial cell senescence and pro-inflammatory response: Implication of Notch signaling in atherosclerosis

(2012) Zhao-Jun Liu et al.   ATHEROSCLEROSIS

Role of Phospholipid Oxidation Products in Atherosclerosis

(2012) Sangderk Lee et al.   CIRCULATION RESEARCH

Effect of interleukin 1β inhibition in cardiovascular disease

(2012) Arman Qamar et al.   CURRENT OPINION IN LIPIDOLOGY

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome

(2012) J. J. Hofmann et al.   DEVELOPMENT

The Notch pathway: a crossroad between the life and death of the endothelium

(2012) Paola Rizzo et al.   EUROPEAN HEART JOURNAL

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

(2012) D. Fukuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diet-Induced Aortic Valve Disease in Mice Haploinsufficient for the Notch Pathway Effector RBPJK/CSL

(2011) Meritxell Nus et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium

(2011) Zhe Zhou et al.   Cell Metabolism

Network for Activation of Human Endothelial Cells by Oxidized Phospholipids

(2011) Casey E. Romanoski et al.   CIRCULATION RESEARCH

Systems Genetics Analysis of Gene-by-Environment Interactions in Human Cells

(2010) Casey E. Romanoski et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Inflammation dysregulates Notch signaling in endothelial cells: Implication of Notch2 and Notch4 to endothelial dysfunction

(2010) Thibaut Quillard et al.   BIOCHEMICAL PHARMACOLOGY

Oxidized Phospholipids Are More Potent Antagonists of Lipopolysaccharide than Inducers of Inflammation

(2010) O. V. Oskolkova et al.   JOURNAL OF IMMUNOLOGY

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

γ-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice

(2009) Toru Aoyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Impaired Notch4 Activity Elicits Endothelial Cell Activation and Apoptosis

(2008) T. Quillard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY