TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling

Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression

(2012) D.F.G. Remst et al.   OSTEOARTHRITIS AND CARTILAGE

The specificities of small molecule inhibitors of the TGFß and BMP pathways

(2011) Janis Vogt et al.   CELLULAR SIGNALLING

CCN2 Is Required for the TGF-β Induced Activation of Smad1 - Erk1/2 Signaling Network

(2011) Sashidhar S. Nakerakanti et al.   PLoS One

Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells

(2010) J.H. Boergermann et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Src is a major signaling component for CTGF induction by TGF-β1 in osteoblasts

(2010) X. Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transforming Growth Factor β Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors

(2009) Katharine H. Wrighton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

(2009) E. N. Blaney Davidson et al.   JOURNAL OF IMMUNOLOGY

Role of transforming growth factor-β superfamily signaling pathways in human disease

(2008) Kelly J. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Molecular requirements for induction of CTGF expression by TGF-β1 in primary osteoblasts

(2008) J.A. Arnott et al.   BONE

TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch

(2008) Irwin M Liu et al.   EMBO JOURNAL

Regulation of connective tissue growth factor (CTGF) by hepatocyte growth factor in human tubular epithelial cells

(2008) S. Kroening et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION