Physiological and pathological role of the ubiquitin-proteasome system in the vascular smooth muscle cell

Calcium Channel Blocker Verapamil Enhances Reticulum Stress and Death Induced by Proteasome Inhibition in Myeloma Cells

(2015) Silke Meister et al.   NEOPLASIA

Redox Control of the Ubiquitin-Proteasome System: From Molecular Mechanisms to Functional Significance

(2011) Franziska Kriegenburg et al.   ANTIOXIDANTS & REDOX SIGNALING

Smooth Muscle Cell Apoptosis Promotes Vessel Remodeling and Repair via Activation of Cell Migration, Proliferation, and Collagen Synthesis

(2011) Haixiang Yu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteasomal Inhibition Promotes ATP-Binding Cassette Transporter A1 (ABCA1) and ABCG1 Expression and Cholesterol Efflux From Macrophages In Vitro and In Vivo

(2011) Masatsune Ogura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)

(2011) Ivette Hernández-Negrete et al.   BIOCHEMICAL JOURNAL

Nitric Oxide Inhibits Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia by Increasing the Ubiquitination and Degradation of UbcH10

(2011) Nick D. Tsihlis et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

AMPKα2 Deletion Exacerbates Neointima Formation by Upregulating Skp2 in Vascular Smooth Muscle Cells

(2011) Ping Song et al.   CIRCULATION RESEARCH

miR-29b Participates in Early Aneurysm Development in Marfan Syndrome

(2011) Denis R. Merk et al.   CIRCULATION RESEARCH

Second Generation Proteasome Inhibitors: Carfilzomib and Immunoproteasome-Specific Inhibitors (IPSIs)

(2011) D. J. Kuhn et al.   CURRENT CANCER DRUG TARGETS

Aging and calorie restriction modulate yeast redox state, oxidized protein removal, and the ubiquitin–proteasome system

(2011) Fernanda Marques da Cunha et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inducible Nitric-oxide Synthase and Nitric Oxide Donor Decrease Insulin Receptor Substrate-2 Protein Expression by Promoting Proteasome-dependent Degradation in Pancreatic β-Cells

(2011) Toshihiro Tanioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Regulation of S Phase Kinase-associated Protein 2 by NR4A Orphan Nuclear Receptor NOR1 in Vascular Smooth Muscle Cells

(2011) Florence Gizard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitric Oxide Increases Lysine 48-Linked Ubiquitination Following Arterial Injury

(2011) Chris S. Oustwani et al.   JOURNAL OF SURGICAL RESEARCH

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Proteasome Inhibition Represses Unfolded Protein Response and Nox4, Sensitizing Vascular Cells to Endoplasmic Reticulum Stress-Induced Death

(2011) Angélica M. Amanso et al.   PLoS One

The N-end rule pathway and regulation by proteolysis

(2011) Alexander Varshavsky   PROTEIN SCIENCE

Protein dislocation from the ER

(2010) Katrin Bagola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Activation of Specific Apoptotic Caspases with an Engineered Small-Molecule-Activated Protease

(2010) Daniel C. Gray et al.   CELL

Sent to Destroy

(2010) Monte S. Willis et al.   CIRCULATION RESEARCH

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER

(2010) Riccardo Bernasconi et al.   CURRENT OPINION IN CELL BIOLOGY

Proliferation unleashed: The role of Skp2 in vascular smooth muscle cell proliferation

(2010) Mark Bond   Frontiers in Bioscience-Landmark

Preventive Effect of a Proteasome Inhibitor on the Formation of Accelerated Atherosclerosis in Rabbits With Uremia

(2010) Bing Feng et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Proteasomal degradation of myocardin is required for its transcriptional activity in vascular smooth muscle cells

(2010) Hao Yin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nox4-Derived H2O2 Mediates Endoplasmic Reticulum Signaling through Local Ras Activation

(2010) R.-F. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

(2010) Lynn Bedford et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein disulfide isomerase overexpression in vascular smooth muscle cells induces spontaneous preemptive NADPH oxidase activation and Nox1 mRNA expression: Effects of nitrosothiol exposure

(2009) Denise C. Fernandes et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteasome inhibitor bortezomib promotes a rupture-prone plaque phenotype in ApoE-deficient mice

(2009) Jozef Leo Herck et al.   BASIC RESEARCH IN CARDIOLOGY

Ubiquitin-mediated control of oncogene and tumor suppressor gene products

(2009) Kyoko Kitagawa et al.   CANCER SCIENCE

Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2

(2009) Henryk Dreger et al.   CARDIOVASCULAR RESEARCH

Tyrosine Nitration of PA700 Activates the 26S Proteasome to Induce Endothelial Dysfunction in Mice With Angiotensin II–Induced Hypertension

(2009) Jian Xu et al.   HYPERTENSION

Inhibitory Effect of Flavonoids on 26S Proteasome Activity

(2009) Tsui-Ling Chang   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

No Splicing, No Dicing: Non-proteolytic Roles of the Ubiquitin-Proteasome System in Transcription

(2009) Thomas Kodadek   JOURNAL OF BIOLOGICAL CHEMISTRY

C Terminus of Hsc70-interacting Protein Promotes Smooth Muscle Cell Proliferation and Survival through Ubiquitin-mediated Degradation of FoxO1

(2009) Fang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination

(2009) James M. Baugh et al.   JOURNAL OF MOLECULAR BIOLOGY

S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo

(2009) Yih-Jer Wu et al.   JOURNAL OF VASCULAR SURGERY

CHIP Represses Myocardin-Induced Smooth Muscle Cell Differentiation via Ubiquitin-Mediated Proteasomal Degradation

(2009) P. Xie et al.   MOLECULAR AND CELLULAR BIOLOGY

The proteasomal system

(2009) Tobias Jung et al.   MOLECULAR ASPECTS OF MEDICINE

Nitric oxide regulates the 26S proteasome in vascular smooth muscle cells

(2009) Muneera R. Kapadia et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

FoxM1 Is a General Target for Proteasome Inhibitors

(2009) Uppoor G. Bhat et al.   PLoS One

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

(2009) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases

(2009) Kathryn M Oliver et al.   ARTHRITIS RESEARCH & THERAPY

Potential Role of CYLD (Cylindromatosis) as a Deubiquitinating Enzyme in Vascular Cells

(2008) Yoichi Takami et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology

(2008) Alan L. Schwartz et al.   Annual Review of Pharmacology and Toxicology

Ubiquitin–proteasome system mediates heme oxygenase-1 degradation through endoplasmic reticulum-associated degradation pathway

(2008) Pu-Hua Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo

(2008) Mark Bond et al.   CARDIOVASCULAR RESEARCH

Targeting of the Proteasome Worsens Atherosclerosis?

(2008) Antje Ludwig et al.   CIRCULATION RESEARCH

Mechanisms of proteasome inhibitor action and resistance in cancer

(2008) David J. McConkey et al.   DRUG RESISTANCE UPDATES

PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts

(2008) Mitsutoshi Asai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

Does inhibition of degradation of hypoxia-inducible factor (HIF) α always lead to activation of HIF? lessons learnt from the effect of proteasomal inhibition on HIF activity

(2007) Stefan Kaluz et al.   JOURNAL OF CELLULAR BIOCHEMISTRY