DPP-4 Inhibitors Repress NLRP3 Inflammasome and Interleukin-1beta via GLP-1 Receptor in Macrophages Through Protein Kinase C Pathway

PKCβ Promotes Vascular Inflammation and Acceleration of Atherosclerosis in Diabetic ApoE Null Mice

(2013) Linghua Kong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR-γ

(2013) Yao Dai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LOX-1, a bridge between GLP-1R and mitochondrial ROS generation in human vascular smooth muscle cells

(2013) Yao Dai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucagon-like Peptide-1 Receptor Agonist Liraglutide Inhibits Endothelin-1 in Endothelial Cell by Repressing Nuclear Factor-Kappa B Activation

(2013) Yao Dai et al.   CARDIOVASCULAR DRUGS AND THERAPY

Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis

(2013) Anna M. Lundberg et al.   CARDIOVASCULAR RESEARCH

Dipeptidyl Peptidase-4 Inhibitor, Sitagliptin, Improves Endothelial Dysfunction in Association With Its Anti-Inflammatory Effects in Patients With Coronary Artery Disease and Uncontrolled Diabetes

(2013) Junichi Matsubara et al.   CIRCULATION JOURNAL

Sitagliptin therapy enhances the number of circulating angiogenic cells and angiogenesis—evaluations in vitro and in the rat critical limb ischemia model

(2013) Sarah Chua et al.   CYTOTHERAPY

Anagliptin, a DPP-4 Inhibitor, Suppresses Proliferation of Vascular Smooth Muscles and Monocyte Inflammatory Reaction and Attenuates Atherosclerosis in Male apo E-Deficient Mice

(2013) Nasib Ervinna et al.   ENDOCRINOLOGY

Plasma from rheumatoid arthritis patients promotes pro-atherogenic cholesterol transport gene expression in THP-1 human macrophages

(2013) Iryna Voloshyna et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

OxLDL-induced IL-1beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation

(2013) Weiwei Liu et al.   INFLAMMATION RESEARCH

TLR4/PKC-mediated tight junction modulation: A clinical marker of chemotherapy-induced gut toxicity?

(2013) Hannah R. Wardill et al.   INTERNATIONAL JOURNAL OF CANCER

Inflammation and Atherosclerosis—Revisited

(2013) Sadip Pant et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Preventive Effect of Dipeptidyl Peptidase-4 Inhibitor on Atherosclerosis Is Mainly Attributable to Incretin's Actions in Nondiabetic and Diabetic Apolipoprotein E-Null Mice

(2013) Michishige Terasaki et al.   PLoS One

NLRP3 activation induces ASC-dependent programmed necrotic cell death, which leads to neutrophilic inflammation

(2013) T Satoh et al.   Cell Death & Disease

Macrophage Activation by Heparanase Is Mediated by TLR-2 and TLR-4 and Associates With Plaque Progression

(2012) Miry Blich et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation

(2012) Yugang Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New strategy for the treatment of type 2 diabetes mellitus with incretin-based therapy

(2012) Mitsuyoshi Namba et al.   Clinical and Experimental Nephrology

Effect of the interleukin-1B gene on serum oxidized low-density lipoprotein levels

(2012) Maria Fernanda Manica-Cattani et al.   CLINICAL BIOCHEMISTRY

Cardiovascular effects of the DPP-4 inhibitors

(2012) Tessey Jose et al.   Diabetes & Vascular Disease Research

ABCA1 Protein Enhances Toll-like Receptor 4 (TLR4)-stimulated Interleukin-10 (IL-10) Secretion through Protein Kinase A (PKA) Activation

(2012) Loretta Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tenascin-C produced by oxidized LDL-stimulated macrophages increases foam cell formation through toll-like receptor-4

(2012) Rui Liu et al.   MOLECULES AND CELLS

Phosphorylation of NLRC4 is critical for inflammasome activation

(2012) Yan Qu et al.   NATURE

Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients

(2011) Paul A. J. Krijnen et al.   BASIC RESEARCH IN CARDIOLOGY

Long-Term Dipeptidyl-Peptidase 4 Inhibition Reduces Atherosclerosis and Inflammation via Effects on Monocyte Recruitment and Chemotaxis

(2011) Zubair Shah et al.   CIRCULATION

Ht31, a Protein Kinase A Anchoring Inhibitor, Induces Robust Cholesterol Efflux and Reverses Macrophage Foam Cell Formation through ATP-binding Cassette Transporter A1

(2010) Loretta Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

Impact of Plasma Oxidized Low-Density Lipoprotein Removal on Atherosclerosis

(2008) Yasushi Ishigaki et al.   CIRCULATION