OxLDL-induced IL-1beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation

Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation

(2012) Yugang Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of macrophage scavenger receptors in atherosclerosis

(2012) Julia Kzhyshkowska et al.   IMMUNOBIOLOGY

Effect of overexpression of human SR-AI on oxLDL uptake and apoptosis in 293T cells

(2011) Hong Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

C-Reactive Protein Uptake by Macrophage Cell Line via Class-A Scavenger Receptor

(2010) Y. Fujita et al.   CLINICAL CHEMISTRY

Cold pre-conditioning neuroprotection depends on TNF-α and is enhanced by blockade of interleukin-11

(2010) Heidi M. Mitchell et al.   JOURNAL OF NEUROCHEMISTRY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

(2008) Jenny Persson et al.   BMC IMMUNOLOGY

Cytokines and atherosclerosis: a comprehensive review of studies in mice

(2008) R. Kleemann et al.   CARDIOVASCULAR RESEARCH

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE