The molecular basis that unifies the metabolism, cellular uptake and chemopreventive activities of dietary isothiocyanates

Proteins as binding targets of isothiocyanates in cancer prevention

(2011) L. Mi et al.   CARCINOGENESIS

Allyl Isothiocyanate Arrests Cancer Cells in Mitosis, and Mitotic Arrest in Turn Leads to Apoptosis via Bcl-2 Protein Phosphorylation

(2011) Feng Geng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A cautionary note on using N-acetylcysteine as an antagonist to assess isothiocyanate-induced reactive oxygen species-mediated apoptosis

(2010) Lixin Mi et al.   ANALYTICAL BIOCHEMISTRY

Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells

(2010) L. Mi et al.   CARCINOGENESIS

Sulforaphane inhibits 4-aminobiphenyl-induced DNA damage in bladder cells and tissues

(2010) Y. Ding et al.   CARCINOGENESIS

Benzyl Isothiocyanate-Mediated Inhibition of Histone Deacetylase Leads to NF- B Turnoff in Human Pancreatic Carcinoma Cells

(2010) S. Batra et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanate

(2010) Renaud Warin et al.   MOLECULAR CARCINOGENESIS

Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention

(2009) Ka Lung Cheung et al.   AAPS Journal

Inhibition of hypoxia inducible factor by phenethyl isothiocyanate

(2009) Xiu-Hong Wang et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of Activator Protein-1 by Sulforaphane Involves Interaction with Cysteine in the cFos DNA-Binding Domain: Implications for Chemoprevention of UVB-Induced Skin Cancer

(2009) S. E. Dickinson et al.   CANCER RESEARCH

Inhibition of bladder cancer development by allyl isothiocyanate

(2009) Arup Bhattacharya et al.   CARCINOGENESIS

Covalent Modification of Lysine Residues by Allyl Isothiocyanate in Physiological Conditions: Plausible Transformation of Isothiocyanate from Thiol to Amine

(2009) Toshiyuki Nakamura et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Antiangiogenic and Proapoptotic Activities of Allyl Isothiocyanate Inhibit Ascites Tumor Growth in Vivo

(2009) Akhilesh Kumar et al.   INTEGRATIVE CANCER THERAPIES

Direct Modification of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor by Dietary Isothiocyanates

(2009) Kristin K. Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes

(2009) Lixin Mi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sulforaphane Suppresses Oligomerization of TLR4 in a Thiol-Dependent Manner

(2009) Hyung Sun Youn et al.   JOURNAL OF IMMUNOLOGY

The Role of STAT-3 in the Induction of Apoptosis in Pancreatic Cancer Cells by Benzyl Isothiocyanate

(2009) R. P. Sahu et al.   JNCI-Journal of the National Cancer Institute

Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of  -tubulin at Cys 12 and suppression of microtubule dynamics

(2009) W. Xu et al.   MOLECULAR CANCER THERAPEUTICS

Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells

(2009) Aiyu Gong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Allyl isothiocyanate as a cancer chemopreventive phytochemical

(2009) Yuesheng Zhang   MOLECULAR NUTRITION & FOOD RESEARCH

Quantification of Sulforaphane Mercapturic Acid Pathway Conjugates in Human Urine by High-Performance Liquid Chromatography and Isotope-Dilution Tandem Mass Spectrometry

(2008) Patricia A. Egner et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Sulforaphane Enhances the Therapeutic Potential of TRAIL in Prostate Cancer Orthotopic Model through Regulation of Apoptosis, Metastasis, and Angiogenesis

(2008) S. Shankar et al.   CLINICAL CANCER RESEARCH

Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells

(2008) Eun-Sun Hwang et al.   FOOD AND CHEMICAL TOXICOLOGY

Covalent Binding to Tubulin by Isothiocyanates

(2008) Lixin Mi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism-Based Inactivation of Human Cytochromes P450s: Experimental Characterization, Reactive Intermediates, and Clinical Implications

(2007) Paul F. Hollenberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY