Bioactive compounds ofCrocus sativusL. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents

New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies

(2014) Celeste De Monte et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antileishmanial Lead Structures from Nature: Analysis of Structure-Activity Relationships of a Compound Library Derived from Caffeic Acid Bornyl Ester

(2014) Jan Glaser et al.   MOLECULES

Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates

(2013) Jed W. Fahey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pylori peptide deformylase activity

(2013) Kunqiang Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthesis, structure–activity relationship analysis and kinetics study of reductive derivatives of flavonoids as Helicobacter pylori urease inhibitors

(2013) Zhu-Ping Xiao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A novel nanobody against urease activity of Helicobacter pylori

(2013) Leila Safaee Ardekani et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Red ginseng extract inhibits the expression of MCP-1 and iNOS in Helicobacter pylori-infected gastric epithelial cells by suppressing the activation of NADPH oxidase and Jak2/Stat3

(2013) Soon Ok Cho et al.   JOURNAL OF ETHNOPHARMACOLOGY

Discovery of a New Class of Natural Product-Inspired Quinazolinone Hybrid as Potent Antileishmanial agents

(2013) Moni Sharma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amazonian Plant Natural Products: Perspectives for Discovery of New Antimalarial Drug Leads

(2013) Adrian Pohlit et al.   MOLECULES

Experimentally Validated Novel Inhibitors of Helicobacter pylori Phosphopantetheine Adenylyltransferase Discovered by Virtual High-Throughput Screening

(2013) Chao-Sheng Cheng et al.   PLoS One

Design of inhibitors of Helicobacter pylori glutamate racemase as selective antibacterial agents: Incorporation of imidazoles onto a core pyrazolopyrimidinedione scaffold to improve bioavailabilty

(2012) Gregory S. Basarab et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular Docking, Kinetics Study, and Structure–Activity Relationship Analysis of Quercetin and Its Analogous as Helicobacter pylori Urease Inhibitors

(2012) Zhu-Ping Xiao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis, biological assay in vitro and molecular docking studies of new Schiff base derivatives as potential urease inhibitors

(2011) Muhammad Adil S. Aslam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions

(2011) Philippe Rasoanaivo et al.   MALARIA JOURNAL

Novel Betulin Derivatives as Antileishmanial Agents with Mode of Action Targeting Type IB DNA Topoisomerase

(2011) S. Chowdhury et al.   MOLECULAR PHARMACOLOGY

Synthesis, selective anti-Helicobacter pylori activity, and cytotoxicity of novel N-substituted-2-oxo-2H-1-benzopyran-3-carboxamides

(2010) Franco Chimenti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Tetrahydrobenzothiophene Derivatives: Conformationally Restricted Inhibitors of Type II Dehydroquinase

(2010) Sonia Paz et al.   ChemMedChem

New Applications and Mechanisms of Action of Saffron and its Important Ingredients

(2010) S. Zahra Bathaie et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Synthesis and anti-Helicobacter pylori activity of 4-(coumarin-3-yl)thiazol-2-ylhydrazone derivatives

(2010) Franco Chimenti et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda

(2010) S. H. I. Kappe et al.   SCIENCE

Emodin targets the β-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization

(2009) Jing Chen et al.   BMC MICROBIOLOGY

Antimicrobial Susceptibility Testing of Helicobacter pylori Determined by Microdilution Method Using a New Medium

(2009) Francesca Sisto et al.   CURRENT MICROBIOLOGY

Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics

(2008) Matthieu Fonvielle et al.   CHEMISTRY-A EUROPEAN JOURNAL

Three flavonoids targeting the β-hydroxyacyl-acyl carrier protein dehydratase fromHelicobacter pylori: Crystal structure characterization with enzymatic inhibition assay

(2008) Liang Zhang et al.   PROTEIN SCIENCE