Gene Silencing by the Polycomb Group Proteins and Associations With Cancer

Bmi1 Is Required for Hedgehog Pathway-Driven Medulloblastoma Expansion

(2015) Lowell Evan Michael et al.   NEOPLASIA

A Region of the Human HOXD Cluster that Confers Polycomb-Group Responsiveness

(2010) Caroline J. Woo et al.   CELL

Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation

(2010) Margaret Rush et al.   Epigenetics

Loss of the CBX7 protein expression correlates with a more aggressive phenotype in pancreatic cancer

(2010) Eva Karamitopoulou et al.   EUROPEAN JOURNAL OF CANCER

BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer

(2010) Xiao-Wei Zhang et al.   Molecular Cancer

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

(2010) Diego Pasini et al.   NATURE

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Non-coding RNAs in Polycomb/Trithorax regulation

(2010) Betül Hekimoglu et al.   RNA Biology

Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancerThis paper is one of a selection of papers published in this Special Issue, entitled The 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal's usual peer review process.

(2009) Randall S. Gieni et al.   Biochemistry and Cell Biology

A Vertebrate Polycomb Response Element Governs Segmentation of the Posterior Hindbrain

(2009) Angela Sing et al.   CELL

Epigenetic gene regulation in stem cells and correlation to cancer

(2009) Lesley A. Mathews et al.   DIFFERENTIATION

Reciprocal expression of Bmi1 and Mel-18 is associated with functioning of primitive hematopoietic cells

(2009) Teruyuki Kajiume et al.   EXPERIMENTAL HEMATOLOGY

The Target of the NSD Family of Histone Lysine Methyltransferases Depends on the Nature of the Substrate

(2009) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Brief

(2009)   NATURE REVIEWS NEUROSCIENCE

Several Distinct Polycomb Complexes Regulate and Co-Localize on the INK4a Tumor Suppressor Locus

(2009) Goedele N. Maertens et al.   PLoS One

RNF2 is the target for phosphorylation by the p38 MAPK and ERK signaling pathways

(2009) Prema S. Rao et al.   PROTEOMICS

Maintenance of Undifferentiated State and Self-Renewal of Embryonic Neural Stem Cells by Polycomb Protein Ring1B

(2009) Mónica Román-Trufero et al.   STEM CELLS

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

(2008) S. Sander et al.   BLOOD

The Polycomb Gene Product BMI1 Contributes to the Maintenance of Tumor-Initiating Side Population Cells in Hepatocellular Carcinoma

(2008) T. Chiba et al.   CANCER RESEARCH

RYBP stabilizes p53 by modulating MDM2

(2008) Deng Chen et al.   EMBO REPORTS

Gene expression profiling of Polycomb, Hox and Meis genes in patients with acute myeloid leukaemia

(2008) Lykke Grubach et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

(2008) D. Pasini et al.   GENES & DEVELOPMENT

The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma

(2008) Motoko Sasaki et al.   LABORATORY INVESTIGATION

Loss of BMI-1 expression is associated with clinical progress of malignant melanoma

(2008) Ingeborg M Bachmann et al.   MODERN PATHOLOGY

SWI/SNF Mediates Polycomb Eviction and Epigenetic Reprogramming of the INK4b-ARF-INK4a Locus

(2008) S. K. Kia et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation

(2008) Wenlai Zhou et al.   MOLECULAR CELL

Brain tumor stem cells and the tumor microenvironment

(2008) Rahul Jandial et al.   Neurosurgical Focus

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

(2008) Q Cao et al.   ONCOGENE

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

(2008) J. S. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE

Expression Parameters of the Polycomb Group Proteins BMI1, SUZ12, RING1 and CBX7 in Urothelial Carcinoma of the Bladder and Their Prognostic Relevance

(2008) S. Hinz et al.   TUMOR BIOLOGY

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics