标题
Interleukin 12: still a promising candidate for tumor immunotherapy?
作者
关键词
Interleukin 12, Cancer immunotherapy, Gene therapy, Cytokine
出版物
CANCER IMMUNOLOGY IMMUNOTHERAPY
Volume 63, Issue 5, Pages 419-435
出版商
Springer Nature
发表日期
2014-02-10
DOI
10.1007/s00262-014-1523-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Intra-arterial interleukin-12 gene delivery combined with chemoembolization: anti-tumor effect in a rabbit hepatocellular carcinoma (HCC) model
- (2013) Xiangwen Xia et al. ACTA RADIOLOGICA
- Antiangiogenic therapy promoted metastasis of hepatocellular carcinoma by suppressing host-derived interleukin-12b in mouse models
- (2013) Xiao-Dong Zhu et al. ANGIOGENESIS
- Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses
- (2013) G. Nizzoli et al. BLOOD
- Immune-suppressive properties of the tumor microenvironment
- (2013) Jürgen C. Becker et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Vaccination with Dendritic Cell/Tumor Fusions following Autologous Stem Cell Transplant Induces Immunologic and Clinical Responses in Multiple Myeloma Patients
- (2013) J. Rosenblatt et al. CLINICAL CANCER RESEARCH
- Phase I trial of a formulated IL-12 plasmid in combination with carboplatin and docetaxel chemotherapy in the treatment of platinum-sensitive recurrent ovarian cancer
- (2013) Khursheed Anwer et al. GYNECOLOGIC ONCOLOGY
- Doxorubicin sensitizes human tumor cells to NK cell- and T-cell-mediated killing by augmented TRAIL receptor signaling
- (2013) Erik Wennerberg et al. INTERNATIONAL JOURNAL OF CANCER
- Randomized Selection Design Trial Evaluating CD8+-Enriched Versus Unselected Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy for Patients With Melanoma
- (2013) Mark E. Dudley et al. JOURNAL OF CLINICAL ONCOLOGY
- Eradication of Liver-Implanted Tumors by Semliki Forest Virus Expressing IL-12 Requires Efficient Long-Term Immune Responses
- (2013) J. I. Quetglas et al. JOURNAL OF IMMUNOLOGY
- Impact of anti-CD25 monoclonal antibody on dendritic cell-tumor fusion vaccine efficacy in a murine melanoma model
- (2013) Chunrui Tan et al. Journal of Translational Medicine
- Cytokine patterns in patients with cancer: a systematic review
- (2013) Bodo E Lippitz LANCET ONCOLOGY
- Enhanced Antitumor Response Mediated by the Codelivery of Paclitaxel and Adenoviral Vector Expressing IL-12
- (2013) Linjie Cao et al. MOLECULAR PHARMACEUTICS
- Collapse of the Tumor Stroma is Triggered by IL-12 Induction of Fas
- (2013) Sid P Kerkar et al. MOLECULAR THERAPY
- Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
- (2013) Stephan A. Grupp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tim-3 alters the balance of IL-12/IL-23 and drives TH17 cells: Role in hepatitis B vaccine failure during hepatitis C infection
- (2013) Jia M. Wang et al. VACCINE
- Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
- (2012) H. J. Pegram et al. BLOOD
- Management of indolent lymphoma: Where are we now and where are we going
- (2012) Matthew A. Lunning et al. BLOOD REVIEWS
- Therapeutic effect of intratumoral administration of DCs with conditional expression of combination of different cytokines
- (2012) Chun Huang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CAR T cells transform to trucks: chimeric antigen receptor–redirected T cells engineered to deliver inducible IL-12 modulate the tumour stroma to combat cancer
- (2012) Markus Chmielewski et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Immunocytokines: a novel class of potent armed antibodies
- (2012) Nadine Pasche et al. DRUG DISCOVERY TODAY
- Interleukin-12: Clinical usage and molecular markers of cancer susceptibility
- (2012) Arseniy E. Yuzhalin et al. GROWTH FACTORS
- CD4+CD25+ Treg derived from hepatocellular carcinoma mice inhibits tumor immunity
- (2012) Xin Chen et al. IMMUNOLOGY LETTERS
- Immunomodulatory effects of low dose chemotherapy and perspectives of its combination with immunotherapy
- (2012) Mariana S. Nars et al. INTERNATIONAL JOURNAL OF CANCER
- Local targets for immune therapy to cancer: Tumor draining lymph nodes and tumor microenvironment
- (2012) Marieke F. Fransen et al. INTERNATIONAL JOURNAL OF CANCER
- IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma
- (2012) Zhi-Zhang Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors
- (2012) Jing Ni et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Immunotherapeutic Synergy Between Anti-CD137 mAb and Intratumoral Administration of a Cytopathic Semliki Forest Virus Encoding IL-12
- (2012) José I Quetglas et al. MOLECULAR THERAPY
- HemaMax™, a Recombinant Human Interleukin-12, Is a Potent Mitigator of Acute Radiation Injury in Mice and Non-Human Primates
- (2012) Lena A. Basile et al. PLoS One
- Sipuleucel-T for the Treatment of Advanced Prostate Cancer
- (2012) Mark W. Frohlich SEMINARS IN ONCOLOGY
- Dendritic/Tumor Fusion Cells as Cancer Vaccines
- (2012) David Avigan et al. SEMINARS IN ONCOLOGY
- Cetuximab therapy in head and neck cancer: Immune modulation with interleukin-12 and other natural killer cell–activating cytokines
- (2012) Eric Luedke et al. SURGERY
- Upregulation of CD200 is associated with Foxp3+ regulatory T cell expansion and disease progression in acute myeloid leukemia
- (2012) Ali Memarian et al. TUMOR BIOLOGY
- Identification and characterization of polyclonal αβ-T cells with dendritic cell properties
- (2012) Mirela Kuka et al. Nature Communications
- A Phase 1 Study of AS1409, a Novel Antibody-Cytokine Fusion Protein, in Patients with Malignant Melanoma or Renal Cell Carcinoma
- (2011) S. M. Rudman et al. CLINICAL CANCER RESEARCH
- IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors
- (2011) Sid P. Kerkar et al. JOURNAL OF CLINICAL INVESTIGATION
- Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
- (2011) David L. Porter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tim-3 Negatively Regulates IL-12 Expression by Monocytes in HCV Infection
- (2011) Ying Zhang et al. PLoS One
- Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma
- (2010) J. Rosenblatt et al. BLOOD
- Enhanced growth inhibition of metastatic lung tumors by intravenous injection of ATRA-cationic liposome/IL-12 pDNA complexes in mice
- (2010) P Charoensit et al. CANCER GENE THERAPY
- IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy
- (2010) Mike W. Helms et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer
- (2010) Rupal Ramakrishnan et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Direct inhibition of human acute myeloid leukemia cell growth by IL-12
- (2010) Elisa Ferretti et al. IMMUNOLOGY LETTERS
- Interleukin 12 a Key Immunoregulatory Cytokine in Infection Applications
- (2010) Therwa Hamza et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- IL-12 and IL-27 Sequential Gene Therapy via Intramuscular Electroporation Delivery for Eliminating Distal Aggressive Tumors
- (2010) Shiguo Zhu et al. JOURNAL OF IMMUNOLOGY
- Alphavirus vectors for cancer therapy
- (2010) Jose I. Quetglas et al. VIRUS RESEARCH
- Phase-I clinical trial of IL-12 plasmid/lipopolymer complexes for the treatment of recurrent ovarian cancer
- (2009) K Anwer et al. GENE THERAPY
- Interleukin-12 Receptor β2: From Cytokine Receptor to Gatekeeper Gene in Human B-Cell Malignancies
- (2009) Vito Pistoia et al. JOURNAL OF CLINICAL ONCOLOGY
- Treatment of disseminated ovarian cancer using nonviral interleukin-12 gene therapy delivered intraperitoneally
- (2009) Jason G. Fewell et al. JOURNAL OF GENE MEDICINE
- Chemotherapeutic Agents in Noncytotoxic Concentrations Increase Antigen Presentation by Dendritic Cells via an IL-12-Dependent Mechanism
- (2009) G. V. Shurin et al. JOURNAL OF IMMUNOLOGY
- A phase I trial of paclitaxel and trastuzumab in combination with interleukin-12 in patients with HER2/neu-expressing malignancies
- (2009) T. S. Bekaii-Saab et al. MOLECULAR CANCER THERAPEUTICS
- Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice
- (2008) Lena A Basile et al. Journal of Translational Medicine
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now