Lung cancer and Toll-like receptors

Toll-like Receptor 3–Mediated Suppression of TRAMP Prostate Cancer Shows the Critical Role of Type I Interferons in Tumor Immune Surveillance

(2010) Arnold I. Chin et al.   CANCER RESEARCH

The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice

(2010) Fang Ma et al.   Cellular & Molecular Immunology

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

CpG-ODN increases the release of VEGF in a mouse model of lung carcinoma

(2010) Rosalinda Sorrentino et al.   INTERNATIONAL JOURNAL OF CANCER

Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

(2010) Julien Cherfils-Vicini et al.   JOURNAL OF CLINICAL INVESTIGATION

Plasmacytoid Dendritic Cells Alter the Antitumor Activity of CpG-Oligodeoxynucleotides in a Mouse Model of Lung Carcinoma

(2010) R. Sorrentino et al.   JOURNAL OF IMMUNOLOGY

Endothelial Cells Augment the Suppressive Function of CD4+CD25+Foxp3+ Regulatory T Cells: Involvement of Programmed Death-1 and IL-10

(2010) T. Bedke et al.   JOURNAL OF IMMUNOLOGY

A Critical Role for Mast Cells and Mast Cell-Derived IL-6 in TLR2-Mediated Inhibition of Tumor Growth

(2010) S. A. Oldford et al.   JOURNAL OF IMMUNOLOGY

TLR2 Agonists Enhance CD8+Foxp3+ Regulatory T Cells and Suppress Th2 Immune Responses during Allergen Immunotherapy

(2010) Y.-G. Tsai et al.   JOURNAL OF IMMUNOLOGY

Role of the Innate Immune Response and Tumor Immunity Associated with Simian Virus 40 Large Tumor Antigen

(2010) D. B. Lowe et al.   JOURNAL OF VIROLOGY

The role of dendritic and epithelial cells as master regulators of allergic airway inflammation

(2010) Bart N Lambrecht et al.   LANCET

Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2

(2010) Ryoko Sawahata et al.   MICROBES AND INFECTION

Impaired Toll-like receptor 7 and 9 signaling: from chronic viral infections to cancer

(2010) Ivan Hirsch et al.   TRENDS IN IMMUNOLOGY

Plasmacytoid Dendritic Cells Prevent Cigarette Smoke andChlamydophila pneumoniae–Induced Th2 Inflammatory Responses

(2009) Rosalinda Sorrentino et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Regulatory Myeloid Suppressor Cells in Health and Disease

(2009) S. Nagaraj et al.   CANCER RESEARCH

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation

(2009) Svetlana P. Chapoval et al.   CLINICAL IMMUNOLOGY

Physiology and Therapeutics of Vascular Endothelial Growth Factor in Tumor Immunosuppression

(2009) Benjamin Johnson et al.   CURRENT MOLECULAR MEDICINE

Developmental plasticity of Th17 and Treg cells

(2009) Yun Kyung Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Mast Cells as Target in Cancer Therapy

(2009) Tom Kormelink et al.   CURRENT PHARMACEUTICAL DESIGN

Toll-like receptor signaling in cell proliferation and survival

(2009) Xinyan Li et al.   CYTOKINE

Phenotype of dendritic cells generated in the presence of non-small cell lung cancer antigens - preliminary report.

(2009) Olga Jankowska et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Macrophages and fibroblasts during inflammation, tissue damage and organ injury

(2009) Trevor Glaros   Frontiers in Bioscience-Landmark

T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity

(2009) Natalia Martin-Orozco et al.   IMMUNITY

Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells

(2009) Stephen McCartney et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

(2009) Lin Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prostaglandin E2 Inhibits IFN-  Secretion and Th1 Costimulation by Human Plasmacytoid Dendritic Cells via E-Prostanoid 2 and E-Prostanoid 4 Receptor Engagement

(2009) D. Fabricius et al.   JOURNAL OF IMMUNOLOGY

Toll-like Receptor 4 Signaling Promotes Tumor Growth

(2009) Che-Hsin Lee et al.   JOURNAL OF IMMUNOTHERAPY

Cancer immunotherapeutic potential of novel small molecule TLR7 and TLR8 agonists

(2009) Svetlana Hamm et al.   Journal of Immunotoxicology

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

High PD-L1/CD86 Ratio on Plasmacytoid Dendritic Cells Correlates With Elevated T-Regulatory Cells in Liver Transplant Tolerance

(2009) Daisuke Tokita et al.   TRANSPLANTATION

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

(2008) Jonathan L. Koff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function

(2008) R Sorrentino et al.   BRITISH JOURNAL OF PHARMACOLOGY

Toll-like receptors expressed in tumor cells: targets for therapy

(2008) Li Yu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Toll-like receptors in the respiratory system: Their roles in inflammation

(2008) Chiaki Iwamura et al.   CURRENT ALLERGY AND ASTHMA REPORTS

IDO: A double-edged sword for TH1/TH2 regulation

(2008) Hui Xu et al.   IMMUNOLOGY LETTERS

Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family

(2008) H. Michael Shepard et al.   JOURNAL OF CLINICAL INVESTIGATION

Toll-like receptors, wound healing, and carcinogenesis

(2008) Johannes Kluwe et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Immune escape as a fundamental trait of cancer: focus on IDO

(2008) G C Prendergast   ONCOGENE

The Balance between Plasmacytoid DC versus Conventional DC Determines Pulmonary Immunity to Virus Infections

(2008) Joost J. Smit et al.   PLoS One