Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family

Phosphorylated Epidermal Growth Factor Receptor on Tumor-Associated Endothelial Cells Is a Primary Target for Therapy with Tyrosine Kinase Inhibitors

(2015) Toshio Kuwai et al.   NEOPLASIA

Modification of the Primary Tumor Microenvironment by Transforming Growth Factor α-Epidermal Growth Factor Receptor Signaling Promotes Metastasis in an Orthotopic Colon Cancer Model

(2008) Takamitsu Sasaki et al.   AMERICAN JOURNAL OF PATHOLOGY

A phase II study of lapatinib monotherapy in chemotherapy-refractory HER2-positive and HER2-negative advanced or metastatic breast cancer

(2008) H. J. Burstein et al.   ANNALS OF ONCOLOGY

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

(2008) Zhang Weihua et al.   CANCER CELL

Equilibrium between Host and Cancer Caused by Effector T Cells Killing Tumor Stroma

(2008) B. Zhang et al.   CANCER RESEARCH

Membrane-anchored growth factors, the epidermal growth factor family: Beyond receptor ligands

(2008) Shigeki Higashiyama et al.   CANCER SCIENCE

c-Src trafficking and co-localization with the EGF receptor promotes EGF ligand-independent EGF receptor activation and signaling

(2008) Mrudula Donepudi et al.   CELLULAR SIGNALLING

Polarized immune responses differentially regulate cancer development

(2008) Magnus Johansson et al.   IMMUNOLOGICAL REVIEWS

IFN-γ– and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

(2008) Bin Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunoglobulin G Fragment C Receptor Polymorphisms and Clinical Efficacy of Trastuzumab-Based Therapy in Patients With HER-2/neu–Positive Metastatic Breast Cancer

(2008) Antonino Musolino et al.   JOURNAL OF CLINICAL ONCOLOGY

ERBB3/HER3 and ERBB2/HER2 Duet in Mammary Development and Breast Cancer

(2008) David F. Stern   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

CXCL12/CXCR4 Transactivates HER2 in Lipid Rafts of Prostate Cancer Cells and Promotes Growth of Metastatic Deposits in Bone

(2008) S. R. Chinni et al.   MOLECULAR CANCER RESEARCH

EGFR Antagonists in Cancer Treatment

(2008) Fortunato Ciardiello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oncogenes and Cancer

(2008) Carlo M. Croce   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunology

(2008) Olivera J. Finn   NEW ENGLAND JOURNAL OF MEDICINE

Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion

(2008) P Arora et al.   ONCOGENE

Epidermal growth factor receptor activation in prostate cancer by three novel missense mutations

(2008) C Q Cai et al.   ONCOGENE

Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

(2008) D L Wheeler et al.   ONCOGENE

Differential binding patterns of monoclonal antibody 2C4 to the ErbB3–p185her2/neu and the EGFR–p185her2/neu complexes

(2008) Z Cai et al.   ONCOGENE

Emerging roles of ADAM and ADAMTS metalloproteinases in cancer

(2007) N. Rocks et al.   BIOCHIMIE

The Epidermal Growth Factor Receptor System in Skin Repair and Inflammation

(2007) Saveria Pastore et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tumor necrosis factor antagonist mechanisms of action: A comprehensive review

(2007) Daniel Tracey et al.   PHARMACOLOGY & THERAPEUTICS