Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors in a rodent brain tumor model

Long-Term Evaluation of a Phase 1 Study of AADC Gene Therapy for Parkinson's Disease

(2012) Gabriele Mittermeyer et al.   HUMAN GENE THERAPY

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

(2012) Omar D Perez et al.   MOLECULAR THERAPY

Type I IFNs signaling and apoptosis resistance in glioblastoma cells

(2011) Andrea Sgorbissa et al.   APOPTOSIS

Tumoricidal bystander effect in the suicide gene therapy using mesenchymal stem cells does not injure normal brain tissues

(2011) Shinji Amano et al.   CANCER LETTERS

Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector

(2011) D. Ostertag et al.   NEURO-ONCOLOGY

Novel Platform for MRI-Guided Convection-Enhanced Delivery of Therapeutics: Preclinical Validation in Nonhuman Primate Brain

(2011) R. Mark Richardson et al.   STEREOTACTIC AND FUNCTIONAL NEUROSURGERY

Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics

(2010) Dali Yin et al.   JOURNAL OF NEUROSURGERY

Optimized cannula design and placement for convection-enhanced delivery in rat striatum

(2009) Dali Yin et al.   JOURNAL OF NEUROSCIENCE METHODS

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

(2008) J. L. Eberling et al.   NEUROLOGY

GENE AND CELL DELIVERY TO THE DEGENERATED STRIATUM

(2008) R. Mark Richardson et al.   NEUROSURGERY

Image-guided convection-enhanced delivery platform in the treatment of neurological diseases

(2008) Massimo S. Fiandaca et al.   Neurotherapeutics