Novel Platform for MRI-Guided Convection-Enhanced Delivery of Therapeutics: Preclinical Validation in Nonhuman Primate Brain

Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics

(2010) Dali Yin et al.   JOURNAL OF NEUROSURGERY

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

(2010) William J Marks et al.   LANCET NEUROLOGY

Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 Vectors

(2010) Xiaomin Su et al.   MOLECULAR THERAPY

Image-guided convection-enhanced delivery of GDNF protein into monkey putamen

(2010) Francisco Gimenez et al.   NEUROIMAGE

Functional Effects of AAV2-GDNF on the Dopaminergic Nigrostriatal Pathway in Parkinsonian Rhesus Monkeys

(2009) Jamie L. Eberling et al.   HUMAN GENE THERAPY

Clinically Relevant Effects of Convection-Enhanced Delivery of AAV2-GDNF on the Dopaminergic Nigrostriatal Pathway in Aged Rhesus Monkeys

(2009) Louisa C. Johnston et al.   HUMAN GENE THERAPY

Safety Evaluation of AAV2-GDNF Gene Transfer into the Dopaminergic Nigrostriatal Pathway in Aged and Parkinsonian Rhesus Monkeys

(2009) Xiaomin Su et al.   HUMAN GENE THERAPY

Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracy

(2009) Philip A. Starr et al.   JOURNAL OF NEUROSURGERY

Image-guided convection-enhanced delivery of muscimol to the primate brain

(2009) John D. Heiss et al.   JOURNAL OF NEUROSURGERY

Poor drug distribution as a possible explanation for the results of the PRECISE trial

(2009) John H. Sampson et al.   JOURNAL OF NEUROSURGERY

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

(2009) C. W. Christine et al.   NEUROLOGY

Future Applications: Gene Therapy

(2009) R.M. Richardson et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Minimally invasive precision brain access using prospective stereotaxy and a trajectory guide

(2008) Alastair J. Martin et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Real-time MR imaging of adeno-associated viral vector delivery to the primate brain

(2008) Massimo S. Fiandaca et al.   NEUROIMAGE

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

(2008) J. L. Eberling et al.   NEUROLOGY

GENE AND CELL DELIVERY TO THE DEGENERATED STRIATUM

(2008) R. Mark Richardson et al.   NEUROSURGERY

Image-guided convection-enhanced delivery platform in the treatment of neurological diseases

(2008) Massimo S. Fiandaca et al.   Neurotherapeutics