Rapamycin suppresses ROS-dependent apoptosis caused by selenomethionine in A549 lung carcinoma cells

Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells

(2011) Yun Ren et al.   BMB Reports

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

Drugging the PI3 Kinome: From Chemical Tools to Drugs in the Clinic

(2010) P. Workman et al.   CANCER RESEARCH

Differential apoptotic response of human cancer cells to organoselenium compounds

(2009) Maiko Suzuki et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer

(2009) Taro Matsuzaki et al.   CANCER SCIENCE

Selenite induces redox-dependent Bax activation and apoptosis in colorectal cancer cells

(2009) Fang Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway

(2009) Nobuko Koshikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Selenite and Genistein on G2/M Cell Cycle Arrest and Apoptosis in Human Prostate Cancer Cells

(2009) Rui Zhao et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Thioredoxin reductase 1 ablation sensitizes colon cancer cells to methylseleninate-mediated cytotoxicity

(2009) Matthew Honeggar et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Selenocystine induces reactive oxygen species–mediated apoptosis in human cancer cells

(2008) Tianfeng Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Base excision repair of oxidative DNA damage and association with cancer and aging

(2008) S. Maynard et al.   CARCINOGENESIS

Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis

(2008) S. Maddika et al.   JOURNAL OF CELL SCIENCE