The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB

Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways

(2013) Chien-Chih Chiu et al.   PLoS One

Synergistic Effect of Bcl-2 and Cyclin A2 on Adverse Recurrence-Free Survival in Stage I Non-small Cell Lung Cancer

(2012) Eunkyung Ko et al.   ANNALS OF SURGICAL ONCOLOGY

Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells

(2012) Samy A. F. Morad et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Effects of Varicocelectomy on Sperm DNA Fragmentation, Mitochondrial Function, Chromatin Condensation, and Apoptosis

(2012) S. La Vignera et al.   JOURNAL OF ANDROLOGY

Simultaneous Targeting of COX-2 and AKT Using Selenocoxib-1-GSH to Inhibit Melanoma

(2012) R. Gowda et al.   MOLECULAR CANCER THERAPEUTICS

Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction

(2012) Ching-Yu Yen et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

C6-Ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth

(2011) Margaret Flowers et al.   BREAST CANCER RESEARCH AND TREATMENT

Acid Sphingomyelinase Contributes to Evodiamine-Induced Apoptosis in Human Gastric Cancer SGC-7901 Cells

(2011) Hai Huang et al.   DNA AND CELL BIOLOGY

Inhibition of activated receptor tyrosine kinases by Sunitinib induces growth arrest and sensitizes melanoma cells to Bortezomib by blocking Akt pathway

(2011) Andree Yeramian et al.   INTERNATIONAL JOURNAL OF CANCER

(−)-Anonaine Induces DNA Damage and Inhibits Growth and Migration of Human Lung Carcinoma H1299 Cells

(2011) Bing-Hung Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest

(2010) Ching-Yu Yen et al.   BMC CANCER

Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations

(2010) Christian Hafner et al.   EXPERIMENTAL DERMATOLOGY

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

(2010) Ruo-Kai Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of NF-κB inducing kinase underlies constitutive NF-κB activation in lung cancer cells

(2010) Yasunori Saitoh et al.   LUNG CANCER

Ceramides: Branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency

(2009) Ji-Hye Kang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Ceramide induces endothelial cell senescence

(2009) Mark E. Venable et al.   CELL BIOCHEMISTRY AND FUNCTION

Fern Plant–Derived Protoapigenone Leads to DNA Damage, Apoptosis, and G2/M Arrest in Lung Cancer Cell Line H1299

(2009) Chien-Chih Chiu et al.   DNA AND CELL BIOLOGY

Acid sphingomyelinase, cell membranes and human disease: Lessons from Niemann-Pick disease

(2009) Edward H. Schuchman   FEBS LETTERS

Lung Cancer

(2008) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE