EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells

Combining AKT inhibition with chloroquine and gefitinib prevents compensatory autophagy and induces cell death in EGFR mutated NSCLC cells

(2015) Sivan M. Bokobza et al.   Oncotarget

Beyond EGFR TKI in EGFR-mutant Non-Small Cell Lung Cancer patients: Main challenges still to be overcome

(2014) J. Remon et al.   CANCER TREATMENT REVIEWS

EZH2 as a potential target in cancer therapy

(2014) Michael T McCabe et al.   Epigenomics

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

(2013) Kyle D. Konze et al.   ACS Chemical Biology

EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

(2013) Yongjie Wei et al.   CELL

Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells

(2013) Yannick D. Benoit et al.   EXPERIMENTAL CELL RESEARCH

MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2 downregulation and increased cytostatic drug sensitivity

(2013) Leibo Xu et al.   JOURNAL OF HEPATOLOGY

The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib

(2013) Yiyu Zou et al.   Journal of Thoracic Oncology

Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer

(2013) Yuan-yuan Li et al.   LUNG CANCER

The future of epigenetic therapy in solid tumours—lessons from the past

(2013) Nilofer Azad et al.   Nature Reviews Clinical Oncology

Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer

(2013) Jean-Yves Douillard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Induction of Autophagy Is an Early Response to Gefitinib and a Potential Therapeutic Target in Breast Cancer

(2013) Wieslawa H. Dragowska et al.   PLoS One

Targeting Epidermal Growth Factor Receptor in the Management of Lung Cancer

(2013) Tony S.K. Mok et al.   SEMINARS IN ONCOLOGY

Update of research on the role of EZH2 in cancer progression

(2013) Liang Shen et al.   OncoTargets and Therapy

Cancer treatment and survivorship statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Concordant KRAS Mutations in Primary and Metastatic Colorectal Cancer Tissue Specimens: A Meta-Analysis and Systematic Review

(2012) Cheng-Bo Han et al.   CANCER INVESTIGATION

Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells

(2012) Yannick D. Benoit et al.   JOURNAL OF CELLULAR PHYSIOLOGY

p62/SQSTM1/A170: Physiology and pathology

(2012) Masaaki Komatsu et al.   PHARMACOLOGICAL RESEARCH

Autophagy inhibition cooperates with erlotinib to induce glioblastoma cell death

(2011) Sandrine Eimer et al.   CANCER BIOLOGY & THERAPY

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

EZH2 Depletion Blocks the Proliferation of Colon Cancer Cells

(2011) Bettina Fussbroich et al.   PLoS One

The regulation of autophagy - unanswered questions

(2010) Y. Chen et al.   JOURNAL OF CELL SCIENCE

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Anti- and pro-tumor functions of autophagy

(2009) Eugenia Morselli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Epigenetics and cancer treatment

(2009) Lasse Sommer Kristensen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

(2008) Xiaohua Shen et al.   MOLECULAR CELL

EGFR Antagonists in Cancer Treatment

(2008) Fortunato Ciardiello et al.   NEW ENGLAND JOURNAL OF MEDICINE