Extracellular acidity, a “reappreciated” trait of tumor environment driving malignancy: perspectives in diagnosis and therapy
出版年份 2014 全文链接
标题
Extracellular acidity, a “reappreciated” trait of tumor environment driving malignancy: perspectives in diagnosis and therapy
作者
关键词
-
出版物
CANCER AND METASTASIS REVIEWS
Volume 33, Issue 2-3, Pages 823-832
出版商
Springer Nature
发表日期
2014-07-02
DOI
10.1007/s10555-014-9506-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Contribution of acidic melanoma cells undergoing epithelial-to-mesenchymal transition to aggressiveness of non-acidic melanoma cells
- (2014) Silvia Peppicelli et al. CLINICAL & EXPERIMENTAL METASTASIS
- Acidic pH via NF-κB favours VEGF-C expression in human melanoma cells
- (2013) Silvia Peppicelli et al. CLINICAL & EXPERIMENTAL METASTASIS
- Dichloroacetate improves immune dysfunction caused by tumor-secreted lactic acid and increases antitumor immunoreactivity
- (2013) Toshimitsu Ohashi et al. INTERNATIONAL JOURNAL OF CANCER
- Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?
- (2013) Stephen Yiu Chuen Choi et al. JOURNAL OF PATHOLOGY
- Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs – an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research
- (2013) Salvador Harguindey et al. Journal of Translational Medicine
- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments
- (2012) Jonathan W. Wojtkowiak et al. CANCER RESEARCH
- Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes
- (2012) A. Calcinotto et al. CANCER RESEARCH
- Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
- (2012) T. Fiaschi et al. CANCER RESEARCH
- Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production
- (2012) Carmela Guido et al. CELL CYCLE
- Multiple Biological Activities of Lactic Acid in Cancer: Influences on Tumor Growth,Angiogenesis and Metastasis
- (2012) Suveera Dhup et al. CURRENT PHARMACEUTICAL DESIGN
- pH regulators in invadosomal functioning: Proton delivery for matrix tasting
- (2012) Lucie Brisson et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Acidosis Promotes Bcl-2 Family-mediated Evasion of Apoptosis
- (2012) Christopher Ryder et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
- (2012) Toni Celià-Terrassa et al. JOURNAL OF CLINICAL INVESTIGATION
- Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity
- (2012) J. J. Provost et al. CELLULAR ONCOLOGY
- The Na+/H+ exchanger NHE1, but not the Na+, cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2
- (2011) Gitte Lauritzen et al. CANCER LETTERS
- Lactate: A Metabolic Key Player in Cancer
- (2011) F. Hirschhaeuser et al. CANCER RESEARCH
- Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF- B/IL-8 Pathway that Drives Tumor Angiogenesis
- (2011) F. Vegran et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Evidence for a stromal-epithelial “lactate shuttle” in human tumors
- (2011) Diana Whitaker-Menezes et al. CELL CYCLE
- Reduction of metastasis using a non-volatile buffer
- (2011) Arig Ibrahim Hashim et al. CLINICAL & EXPERIMENTAL METASTASIS
- Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
- (2011) Anna N. Mendler et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of K562 leukemia angiogenesis and growth by selective Na+/H+ exchanger inhibitor cariporide through down-regulation of pro-angiogenesis factor VEGF
- (2011) Wei Gao et al. LEUKEMIA RESEARCH
- Is there a role for carbohydrate restriction in the treatment and prevention of cancer?
- (2011) Rainer J Klement et al. Nutrition & Metabolism
- Acidic Extracellular pH Promotes Activation of Integrin αvβ3
- (2011) Ranjani K. Paradise et al. PLoS One
- Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)
- (2011) Fabrice Lucien et al. PLoS One
- Lymphangiogenesis: Molecular Mechanisms and Future Promise
- (2010) Tuomas Tammela et al. CELL
- Acidic stress promotes a glioma stem cell phenotype
- (2010) A B Hjelmeland et al. CELL DEATH AND DIFFERENTIATION
- Novel invadopodia components revealed by differential proteomic analysis
- (2010) Francesca Attanasio et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Tumor pH and Its Measurement
- (2010) X. Zhang et al. JOURNAL OF NUCLEAR MEDICINE
- Biological Effects of a New Vacuolar-H,+-ATPase Inhibitor in Colon Carcinoma Cell Lines
- (2009) Rosanna Supino et al. Annals of the New York Academy of Sciences
- Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases
- (2009) I. F. Robey et al. CANCER RESEARCH
- The Potential Role of Systemic Buffers in Reducing Intratumoral Extracellular pH and Acid-Mediated Invasion
- (2009) A. S. Silva et al. CANCER RESEARCH
- A Novel Technology for the Imaging of Acidic Prostate Tumors by Positron Emission Tomography
- (2009) A. L. Vavere et al. CANCER RESEARCH
- pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
- (2009) Angelo De Milito et al. INTERNATIONAL JOURNAL OF CANCER
- EMT: When epithelial cells decide to become mesenchymal-like cells
- (2009) Raghu Kalluri JOURNAL OF CLINICAL INVESTIGATION
- Cell-cell and intracellular lactate shuttles
- (2009) George A. Brooks JOURNAL OF PHYSIOLOGY-LONDON
- Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
- (2009) Olivier Feron RADIOTHERAPY AND ONCOLOGY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Protons extruded by NHE1: Digestive or glue?
- (2008) C STOCK et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Is cancer a disease of abnormal cellular metabolism? New angles on an old idea
- (2008) Ralph J Deberardinis GENETICS IN MEDICINE
- Acidic pre-conditioning suppresses apoptosis and increases expression of Bcl-xL in coronary endothelial cells under simulated ischaemia
- (2008) S. Kumar et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
- (2008) Claudiu T. Supuran NATURE REVIEWS DRUG DISCOVERY
- Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling
- (2008) J. Srivastava et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers
- (2008) Julia Ling-Yu Chen et al. PLoS Genetics
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation