Acidosis Promotes Bcl-2 Family-mediated Evasion of Apoptosis

Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1

(2011) Felix M. Wensveen et al.   APOPTOSIS

The Novel Bcl-2 Inhibitor ABT-737 Is More Effective in Hypoxia and Is Able to Reverse Hypoxia-Induced Drug Resistance in Neuroblastoma Cells

(2011) T. Klymenko et al.   MOLECULAR CANCER THERAPEUTICS

Glucocorticoid-Mediated Repression of the Oncogenic microRNA Cluster miR-17∼92 Contributes to the Induction of Bim and Initiation of Apoptosis

(2011) Jason K. Molitoris et al.   MOLECULAR ENDOCRINOLOGY

Activation of GPR4 by Acidosis Increases Endothelial Cell Adhesion through the cAMP/Epac Pathway

(2011) Aishe Chen et al.   PLoS One

Post-transcriptional and post-translational regulation of Bcl2: Figure 1

(2010) Shaun Willimott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Blockade of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase and Murine Double Minute Synergistically Induces Apoptosis in Acute Myeloid Leukemia via BH3-Only Proteins Puma and Bim

(2010) W. Zhang et al.   CANCER RESEARCH

Rethinking the Warburg Effect with Myc Micromanaging Glutamine Metabolism

(2010) C. V. Dang   CANCER RESEARCH

Targeting mitochondria for cancer therapy

(2010) David M. Hockenbery   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

ζ-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia

(2010) Andrea Lapucci et al.   FASEB JOURNAL

Mechanism of Regulation ofbcl-2mRNA by Nucleolin and A+U-rich Element-binding Factor 1 (AUF1)

(2010) Daniella Ishimaru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells

(2010) Jonathan L. Coloff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

pH control mechanisms of tumor survival and growth

(2010) Scott K. Parks et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Sugar-free approaches to cancer cell killing

(2010) N El Mjiyad et al.   ONCOGENE

The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor

(2010) Y. Ihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamine addiction: a new therapeutic target in cancer

(2010) David R. Wise et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

(2010) M Fricker et al.   Cell Death & Disease

Acid-sensing by the T cell death-associated gene 8 (TDAG8) receptor cloned from rat brain

(2009) Jennifer McGuire et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner

(2009) L. C. Kottyan et al.   BLOOD

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

(2009) R J DeBerardinis et al.   ONCOGENE

Acidic preconditioning protects endothelial cells against apoptosis through p38- and Akt-dependent Bcl-xL overexpression

(2008) Jan-Paul Flacke et al.   APOPTOSIS

Tumour cell survival signalling by the ERK1/2 pathway

(2008) K Balmanno et al.   CELL DEATH AND DIFFERENTIATION

Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

(2008) M Vogler et al.   CELL DEATH AND DIFFERENTIATION

Relations between the mitogen-activated protein kinase and the cAMP-dependent protein kinase pathways: Comradeship and hostility

(2008) Nancy Gerits et al.   CELLULAR SIGNALLING

The Bone Marrow Microenvironment as a Tumor Sanctuary and Contributor to Drug Resistance

(2008) M. B. Meads et al.   CLINICAL CANCER RESEARCH

Pharmacological PKA Inhibition: All May Not Be What It Seems

(2008) A. J. Murray   Science Signaling