Gene expression-based chemical genomics identifies heat-shock protein 90 inhibitors as potential therapeutic drugs in cholangiocarcinoma

Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins

(2011) Kyung-Hun Lee et al.   CANCER SCIENCE

Development of molecularly targeted therapies in biliary tract cancers: Reassessing the challenges and opportunities

(2011) Andrew X. Zhu et al.   HEPATOLOGY

Gene Expression-Based Chemical Genomics Identifies Potential Therapeutic Drugs in Hepatocellular Carcinoma

(2011) Ming-Huang Chen et al.   PLoS One

Characterization of a novel rat cholangiocarcinoma cell culture model-CGCCA

(2011) Chun-Nan Yeh   WORLD JOURNAL OF GASTROENTEROLOGY

Transcript Profiling and RNA Interference as Tools To Identify Small Molecule Mechanisms and Therapeutic Potential

(2010) Rahul Palchaudhuri et al.   ACS Chemical Biology

Hepatectomy With Simultaneous Resection of the Portal Vein and Hepatic Artery for Advanced Perihilar Cholangiocarcinoma

(2010) Masato Nagino et al.   ANNALS OF SURGERY

Cholangiocarcinoma: Update and future perspectives

(2010) Manuela Gatto et al.   DIGESTIVE AND LIVER DISEASE

Genetics of Biliary Tract Cancers and Emerging Targeted Therapies

(2010) Aram F. Hezel et al.   JOURNAL OF CLINICAL ONCOLOGY

Mechanistic Evaluation of the Novel HSP90 Inhibitor NVP-AUY922 in Adult and Pediatric Glioblastoma

(2010) N. Gaspar et al.   MOLECULAR CANCER THERAPEUTICS

KRAS Mutations and Sensitivity to Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer: Practical Application of Patient Selection

(2009) Antonio Jimeno et al.   JOURNAL OF CLINICAL ONCOLOGY

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

(2008) S. A. Eccles et al.   CANCER RESEARCH

Animal PET for Thioacetamide-Induced Rat Cholangiocarcinoma: A Novel and Reliable Platform

(2008) Chun-Nan Yeh et al.   MOLECULAR IMAGING AND BIOLOGY

Identification of osteopontin as the most consistently over-expressed gene in intrahepatic cholangiocarcinoma: Detection by oligonucleotide microarray and real-time PCR analysis

(2008) Holger G Hass et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Cholangiocarcinoma: A compact review of the literature

(2008) Yucel Ustundag et al.   WORLD JOURNAL OF GASTROENTEROLOGY

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

(2007) Paul A. Brough et al.   JOURNAL OF MEDICINAL CHEMISTRY