Role and Regulation of Vascularization Processes in Endochondral Bones

N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells

(2012) A. M. Greenbaum et al.   BLOOD

Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells

(2012) O. Bromberg et al.   BLOOD

Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect

(2012) Sanjay Kumar et al.   BONE

The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO

(2012) Erinn B. Rankin et al.   CELL

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation

(2012) Yanqiu Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation

(2012) Muneaki Ishijima et al.   MATRIX BIOLOGY

Hypoxia-driven pathways in bone development, regeneration and disease

(2012) Christa Maes et al.   Nature Reviews Rheumatology

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Transcriptional Regulation of Vascular Endothelial Growth Factor (VEGF) by Osteoblast-specific Transcription Factor Osterix (Osx) in Osteoblasts

(2011) Wanjin Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region-specific changes in vascularization

(2011) Ingrid J Poulton et al.   JOURNAL OF BONE AND MINERAL RESEARCH

VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival

(2011) Christa Maes et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Building strong bones: molecular regulation of the osteoblast lineage

(2011) Fanxin Long   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Osteoblastic and Vascular Endothelial Niches, Their Control on Normal Hematopoietic Stem Cells, and Their Consequences on the Development of Leukemia

(2011) Bella S. Guerrouahen et al.   Stem Cells International

Establishment and regulation of the HSC niche: Roles of osteoblastic and vascular compartments

(2010) Suleyman Coskun et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

Complementary interplay between matrix metalloproteinase-9, vascular endothelial growth factor and osteoclast function drives endochondral bone formation

(2010) N. Ortega et al.   Disease Models & Mechanisms

Impaired remodeling phase of fracture repair in the absence of matrix metalloproteinase-2

(2010) S. Lieu et al.   Disease Models & Mechanisms

Bone vascularization and remodeling

(2010) Marie-Hélène Lafage-Proust et al.   JOINT BONE SPINE

Signaling networks in RUNX2-dependent bone development

(2010) Toshihisa Komori   JOURNAL OF CELLULAR BIOCHEMISTRY

Mesenchymal Stem Cells Expressing Osteogenic and Angiogenic Factors Synergistically Enhance Bone Formation in a Mouse Model of Segmental Bone Defect

(2010) Sanjay Kumar et al.   MOLECULAR THERAPY

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells

(2010) Hideki Kobayashi et al.   NATURE CELL BIOLOGY

Septoclast Deficiency Accompanies Postnatal Growth Plate Chondrodysplasia in the Toothless (tl) Osteopetrotic, Colony-Stimulating Factor-1 (CSF-1)-Deficient Rat and Is Partially Responsive to CSF-1 Injections

(2009) Alison Gartland et al.   AMERICAN JOURNAL OF PATHOLOGY

Hematopoietic Stem Cells Do Not Depend on N-Cadherin to Regulate Their Maintenance

(2009) Mark J. Kiel et al.   Cell Stem Cell

The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf

(2009) I. Eshkar-Oren et al.   DEVELOPMENT

Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

(2009) Christa Maes et al.   EMBO JOURNAL

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF

(2009) Ernestina Schipani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

(2009) Ryan C. Riddle et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

A Physical Mechanism for Coupling Bone Resorption and Formation in Adult Human Bone

(2008) Thomas Levin Andersen et al.   AMERICAN JOURNAL OF PATHOLOGY

Matrix metalloproteinases and bone

(2008) Stephen M. Krane et al.   BONE

Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population

(2008) Zana Kalajzic et al.   BONE

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

Fracture vascularity and bone healing: A systematic review of the role of VEGF

(2008) N.C. Keramaris et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Bone Formation During Distraction Osteogenesis Is Dependent on Both VEGFR1 and VEGFR2 Signaling

(2008) Kimberly A Jacobsen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Skeletal Cell Fate Decisions Within Periosteum and Bone Marrow During Bone Regeneration

(2008) Céline Colnot   JOURNAL OF BONE AND MINERAL RESEARCH

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Detection of functional haematopoietic stem cell niche using real-time imaging

(2008) Yucai Xie et al.   NATURE

Bone remodeling during fracture repair: The cellular picture

(2008) Aaron Schindeler et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Skeletal stem/osteoprogenitor cells: Current concepts, alternate hypotheses, and relationship to the bone remodeling compartment

(2007) Ulrike I. Mödder et al.   JOURNAL OF CELLULAR BIOCHEMISTRY