Targeting mitochondrial cardiolipin and the cytochromec/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis

Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice

(2013) Michael P. Siegel et al.   AGING CELL

Multifaceted Effects of ATP on Cardiolipin-Bound Cytochrome c

(2013) Erik J. Snider et al.   BIOCHEMISTRY

Barth syndrome: Cellular compensation of mitochondrial dysfunction and apoptosis inhibition due to changes in cardiolipin remodeling linked to tafazzin (TAZ) gene mutation

(2013) François Gonzalvez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

(2013) Hazel H Szeto   BRITISH JOURNAL OF PHARMACOLOGY

Redox-dependent increases in glutathione reductase and exercise preconditioning: role of NADPH oxidase and mitochondria

(2013) Chad R. Frasier et al.   CARDIOVASCULAR RESEARCH

Global Proteomics and Pathway Analysis of Pressure-Overload–Induced Heart Failure and Its Attenuation by Mitochondrial-Targeted Peptides

(2013) Dao-Fu Dai et al.   Circulation-Heart Failure

Immobilization-induced activation of key proteolytic systems in skeletal muscles is prevented by a mitochondria-targeted antioxidant

(2013) Erin E. Talbert et al.   JOURNAL OF APPLIED PHYSIOLOGY

A mitochondrial bioenergetic etiology of disease

(2013) Douglas C. Wallace   JOURNAL OF CLINICAL INVESTIGATION

The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin

(2013) A. V. Birk et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Bioenergetics in human evolution and disease: implications for the origins of biological complexity and the missing genetic variation of common diseases

(2013) D. C. Wallace   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mitochondrially targeted compounds and their impact on cellular bioenergetics

(2013) Colin Reily et al.   Redox Biology

Mitochondrial permeability transition in the diabetic heart: Contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury

(2012) Ruben C. Sloan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Phosphatidylethanolamine and Cardiolipin Differentially Affect the Stability of Mitochondrial Respiratory Chain Supercomplexes

(2012) Lena Böttinger et al.   JOURNAL OF MOLECULAR BIOLOGY

Reduction of Ischemia/Reperfusion Injury With Bendavia, a Mitochondria‐Targeting Cytoprotective Peptide

(2012) Robert A. Kloner et al.   Journal of the American Heart Association

Mitochondria targeting of non-peroxidizable triphenylphosphonium conjugated oleic acid protects mouse embryonic cells against apoptosis: Role of cardiolipin remodeling

(2011) Yulia Y. Tyurina et al.   FEBS LETTERS

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

(2011) M. J. Calkins et al.   HUMAN MOLECULAR GENETICS

Mitochondrial-targeted antioxidants protect skeletal muscle against immobilization-induced muscle atrophy

(2011) Kisuk Min et al.   JOURNAL OF APPLIED PHYSIOLOGY

Superoxide Flashes

(2011) Qi Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effects of ATP and sodium chloride on the cytochrome c–cardiolipin interaction: The contrasting behavior of the horse heart and yeast proteins

(2011) Federica Sinibaldi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitochondria-Targeted Peptide Accelerates ATP Recovery and Reduces Ischemic Kidney Injury

(2011) H. H. Szeto et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Novel Therapies Targeting Inner Mitochondrial Membrane—From Discovery to Clinical Development

(2011) Hazel H. Szeto et al.   PHARMACEUTICAL RESEARCH

Conformational properties of cardiolipin-bound cytochrome c

(2011) J. Hanske et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Mitochondria-targeted Aromatic-cationic Peptides for Neurodegenerative Diseases

(2010) Hazel H. Szeto   Annals of the New York Academy of Sciences

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oxidative stress, mitochondrial bioenergetics, and cardiolipin in aging

(2010) Giuseppe Paradies et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity

(2009) Lichuan Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of cardiolipin in the structural organization of mitochondrial membranes

(2009) Michael Schlame et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria

(2009) Maurizio Sorice et al.   FEBS LETTERS

Insights into Cytochromec−Cardiolipin Interaction. Role Played by Ionic Strength†

(2008) Federica Sinibaldi et al.   BIOCHEMISTRY

Mitochondria-targeted disruptors and inhibitors of cytochromec/cardiolipin peroxidase complexes: A new strategy in anti-apoptotic drug discovery

(2008) Valerian E. Kagan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mitochondria-Targeted Cytoprotective Peptides for Ischemia–Reperfusion Injury

(2007) Hazel H. Szeto   ANTIOXIDANTS & REDOX SIGNALING