Levels of heroin and its metabolites in blood and brain extracellular fluid after i.v. heroin administration to freely moving rats

Determination of Heroin and Its Main Metabolites in Small Sample Volumes of Whole Blood and Brain Tissue by Reversed-Phase Liquid Chromatography-Tandem Mass Spectrometry

(2013) R. Karinen et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Dynamic vaccine blocks relapse to compulsive intake of heroin

(2013) J. E. Schlosburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developing a Vaccine Against Multiple Psychoactive Targets: A Case Study of Heroin

(2012) G. Neil Stowe et al.   CNS & Neurological Disorders-Drug Targets

Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats

(2012) M. Pravetoni et al.   VACCINE

Simultaneous measurement of heroin and its metabolites in brain extracellular fluid by microdialysis and ultra performance liquid chromatography tandem mass spectrometry

(2012) A. Gottas et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice

(2011) Fernando Boix et al.   ADDICTION BIOLOGY

Vaccines against morphine/heroine and its use as effective medication for preventing relapse to opiate addictive behaviors

(2010) Benito Anton et al.   Human vaccines & immunotherapeutics

Active-Site Concentrations of Chemicals - Are They a Better Predictor of Effect than Plasma/Organ/Tissue Concentrations?

(2009) Margareta Hammarlund-Udenaes   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Molecular Insights Into μ Opioid Pharmacology

(2009) Gavril W. Pasternak   CLINICAL JOURNAL OF PAIN

Anti-drug vaccines to treat substance abuse

(2009) Berma M Kinsey et al.   IMMUNOLOGY AND CELL BIOLOGY

Increased Locomotor Activity Induced by Heroin in Mice: Pharmacokinetic Demonstration of Heroin Acting as a Prodrug for the Mediator 6-Monoacetylmorphine in Vivo

(2009) J. M. Andersen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions

(2009) Y.-X. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The neurocircuitry of addiction: an overview

(2008) M W Feltenstein et al.   BRITISH JOURNAL OF PHARMACOLOGY

Isolation and characterization of new exon 11-associated N-terminal splice variants of the human mu opioid receptor gene

(2008) Jin Xu et al.   JOURNAL OF NEUROCHEMISTRY