RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects

Developmental expression of chemokine-like factor 1, a novel member of chemokines family, in postnatal rat cerebral cortex

(2012) Zhen-Zhen Wang et al.   NEUROSCIENCE LETTERS

GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses

(2011) O Bruno et al.   BRITISH JOURNAL OF PHARMACOLOGY

Stress and Glucocorticoids Impair Memory Retrieval via  2-Adrenergic, Gi/o-Coupled Suppression of cAMP Signaling

(2011) K. Schutsky et al.   JOURNAL OF NEUROSCIENCE

Phosphodiesterase-4D Knock-Out and RNA Interference-Mediated Knock-Down Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling

(2011) Y.-F. Li et al.   JOURNAL OF NEUROSCIENCE

New paradigms in cAMP signalling

(2011) Ferenc A. Antoni   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Abnormal prefrontal activity subserving attentional control of emotion in remitted depressed patients during a working memory task with emotional distracters

(2011) R. Kerestes et al.   PSYCHOLOGICAL MEDICINE

CREB: a multifaceted regulator of neuronal plasticity and protection

(2010) Kensuke Sakamoto et al.   JOURNAL OF NEUROCHEMISTRY

Selective Changes in Thin Spine Density and Morphology in Monkey Prefrontal Cortex Correlate with Aging-Related Cognitive Impairment

(2010) D. Dumitriu et al.   JOURNAL OF NEUROSCIENCE

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

(2010) Viktor Lakics et al.   NEUROPHARMACOLOGY

Chemokine-like factor 1, a novel cytokine, induces nerve cell migration through the non-extracellular Ca2+-dependent tyrosine kinases pathway

(2009) Zhen-Zhen Wang et al.   BRAIN RESEARCH

Shikonin, an ingredient of Lithospermum erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells

(2009) Yi Zhang et al.   CANCER LETTERS

Cyclic AMP-Specific Phosphodiesterase-4 as a Target for the Development of Antidepressant Drugs

(2009) Han-Ting Zhang   CURRENT PHARMACEUTICAL DESIGN

Shu-Gan-Liang-Xue Decoction, a Chinese herbal formula, down-regulates the expression of steroid sulfatase genes in human breast carcinoma MCF-7 cells

(2009) Yi Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety

(2009) Alex B Burgin et al.   NATURE BIOTECHNOLOGY

Antidepressant- and Anxiolytic-like Effects of the Phosphodiesterase-4 Inhibitor Rolipram on Behavior Depend on Cyclic AMP Response Element Binding Protein-Mediated Neurogenesis in the Hippocampus

(2009) Yun-Feng Li et al.   NEUROPSYCHOPHARMACOLOGY

Reversal of long-term dendritic spine alterations in Alzheimer disease models

(2009) D. L. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ex vivo study of 5-HT1A and 5-HT7 receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia

(2008) G. Perez-García et al.   BEHAVIOURAL BRAIN RESEARCH

PDE4 inhibitors: current status

(2008) D Spina   BRITISH JOURNAL OF PHARMACOLOGY

Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells

(2008) J.-W. Wang et al.   JOURNAL OF NEUROSCIENCE

Changes in neuronal excitability serve as a mechanism of long-term memory for operant conditioning

(2008) Riccardo Mozzachiodi et al.   NATURE NEUROSCIENCE

Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats

(2008) K. Rutten et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement

(2008) Olga A. H. Reneerkens et al.   PSYCHOPHARMACOLOGY