标题
The structure and function of the glucagon-like peptide-1 receptor and its ligands
作者
关键词
-
出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 166, Issue 1, Pages 27-41
出版商
Wiley
发表日期
2011-09-28
DOI
10.1111/j.1476-5381.2011.01687.x
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Site-specific PEGylation of exenatide analogues markedly improved their glucoregulatory activity
- (2011) Nian Gong et al. BRITISH JOURNAL OF PHARMACOLOGY
- GLP-1 for type 2 diabetes
- (2011) Bo Ahrén EXPERIMENTAL CELL RESEARCH
- Refinement of Glucagon-like Peptide 1 Docking to Its Intact Receptor Using Mid-region Photolabile Probes and Molecular Modeling
- (2011) Laurence J. Miller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional association of the N-terminal residues with the central region in glucagon-related peptides
- (2011) James T. Patterson et al. JOURNAL OF PEPTIDE SCIENCE
- Biomimetic Screening of Class-B G Protein-Coupled Receptors
- (2011) Christian Devigny et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Novel Human-Based Receptor Antagonist of Sustained Action Reveals Body Weight Control by Endogenous GLP-1
- (2010) James T. Patterson et al. ACS Chemical Biology
- Role of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptor
- (2010) Quan Chen et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Recombinant Expression, in Vitro Refolding, and Biophysical Characterization of the Human Glucagon-like Peptide-1 Receptor
- (2010) Kathrin Schröder-Tittmann et al. BIOCHEMISTRY
- Structural study of an active analog of EX-4 in solution and micelle associated states
- (2010) Shuo Wang et al. BIOPOLYMERS
- The major determinant of exendin-4/glucagon-like peptide 1 differential affinity at the rat glucagon-like peptide 1 receptor N-terminal domain is a hydrogen bond from SER-32 of exendin-4
- (2010) RJ Mann et al. BRITISH JOURNAL OF PHARMACOLOGY
- Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets
- (2010) K. W. Sloop et al. DIABETES
- Spatial Approximations between Residues 6 and 12 in the Amino-terminal Region of Glucagon-like Peptide 1 and Its Receptor
- (2010) Quan Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutational and Cysteine Scanning Analysis of the Glucagon Receptor N-terminal Domain
- (2010) Martine Prévost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development of Potent Glucagon-like Peptide-1 Agonists with High Enzyme Stability via Introduction of Multiple Lactam Bridges
- (2010) Eunice N. Murage et al. JOURNAL OF MEDICINAL CHEMISTRY
- Charge inversion at position 68 of the glucagon and glucagon-like peptide-1 receptors supports selectivity in hormone action
- (2010) Jonathan W. Day et al. JOURNAL OF PEPTIDE SCIENCE
- Comparative Effects of the Endogenous Agonist Glucagon-Like Peptide-1 (GLP-1)-(7-36) Amide and the Small-Molecule Ago-Allosteric Agent "Compound 2" at the GLP-1 Receptor
- (2010) K. Coopman et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Modulation of the Glucagon-Like Peptide-1 Receptor Signaling by Naturally Occurring and Synthetic Flavonoids
- (2010) D. Wootten et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening
- (2010) C. Koole et al. MOLECULAR PHARMACOLOGY
- Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket
- (2010) Rosalind J. Mann et al. PEPTIDES
- Importance of lipid-exposed residues in transmembrane segment four for family B calcitonin receptor homo-dimerization
- (2010) Kaleeckal G. Harikumar et al. REGULATORY PEPTIDES
- GLP-1 protects β-cells against apoptosis by enhancing the activity of an IGF-2/IGF1-receptor autocrine loop
- (2010) Marion Cornu et al. Islets
- Liraglutide: A Once-Daily Incretin Mimetic for the Treatment of Type 2 Diabetes Mellitus
- (2009) Joshua J Neumiller et al. ANNALS OF PHARMACOTHERAPY
- Role of the signal peptide in the synthesis and processing of the glucagon-like peptide-1 receptor
- (2009) Y Huang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Insulin-releasing and metabolic effects of small molecule GLP-1 receptor agonist 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline
- (2009) Nigel Irwin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Molecular Basis of Glucagon-like Peptide 1 Docking to Its Intact Receptor Studied with Carboxyl-terminal Photolabile Probes
- (2009) Quan Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor
- (2009) Christina Rye Underwood et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Eleven Amino Acid Glucagon-like Peptide-1 Receptor Agonists with Antidiabetic Activity
- (2009) Claudio Mapelli et al. JOURNAL OF MEDICINAL CHEMISTRY
- A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
- (2009) Jonathan W Day et al. Nature Chemical Biology
- Passing the baton in class B GPCRs: peptide hormone activation via helix induction?
- (2009) Christoph Parthier et al. TRENDS IN BIOCHEMICAL SCIENCES
- Search for α-helical propensity in the receptor-bound conformation of glucagon-like peptide-1
- (2008) Eunice N. Murage et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain
- (2008) Steffen Runge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular modeling of the three-dimensional structure of GLP-1R and its interactions with several agonists
- (2008) Fu Lin et al. JOURNAL OF MOLECULAR MODELING
- Insights into the Structural Basis of Endogenous Agonist Activation of Family B G Protein-Coupled Receptors
- (2008) Maoqing Dong et al. MOLECULAR ENDOCRINOLOGY
- GLP-1 (9-36) Amide, Cleavage Product of GLP-1 (7-36) Amide, Is a Glucoregulatory Peptide
- (2008) Dariush Elahi et al. Obesity
- Boc5, a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist, Invokes Sustained Glycemic Control and Weight Loss in Diabetic Mice
- (2008) Haoran Su et al. PLoS One
- Class-B GPCR activation: is ligand helix-capping the key?
- (2008) Jean-Michel Neumann et al. TRENDS IN BIOCHEMICAL SCIENCES
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