5-HT6 receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms

Effects of 5-HT6 antagonists, Ro-4368554 and SB-258585, in tests used for the detection of cognitive enhancement and antipsychotic-like activity

(2011) Andreas Gravius et al.   BEHAVIOURAL PHARMACOLOGY

Central nervous system effects of the interaction between risperidone (single dose) and the 5-HT6 antagonist SB742457 (repeated doses) in healthy men

(2011) Marieke Liem-Moolenaar et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Guide to Receptors and Channels (GRAC), 5th edition

(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-HT6 receptor and cognition

(2011) Xabier Codony et al.   CURRENT OPINION IN PHARMACOLOGY

ST1936 stimulates cAMP, Ca2+, ERK1/2 and Fyn kinase through a full activation of cloned human 5-HT6 receptors

(2011) Teresa Riccioni et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Two novel 5-HT6 receptor antagonists ameliorate scopolamine-induced memory deficits in the object recognition and object location tasks in Wistar rats

(2011) N.M.W.J. de Bruin et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Activation of 5-HT6 receptors inhibits corticostriatal glutamatergic transmission

(2011) Annalisa Tassone et al.   NEUROPHARMACOLOGY

Influence of social isolation in the rat on serotonergic function and memory – Relevance to models of schizophrenia and the role  of 5-HT6 receptors

(2011) Charles A. Marsden et al.   NEUROPHARMACOLOGY

The 5-HT6 receptor agonist EMD 386088 produces antidepressant and anxiolytic effects in rats after intrahippocampal administration

(2011) Agnieszka Nikiforuk et al.   PSYCHOPHARMACOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Double-Blind, Controlled Phase II Study of a 5-HT6 Receptor Antagonist, SB-742457, in Alzheimers Disease

(2010) G. Maher-Edwards et al.   Current Alzheimer Research

SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study

(2010) Gareth Maher-Edwards et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Physical Interaction of Jab1 with Human Serotonin 6 G-protein-coupled Receptor and Their Possible Roles in Cell Survival

(2010) Hyung-Mun Yun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat

(2010) Ian Kendall et al.   PSYCHOPHARMACOLOGY

The mGluR2/3 agonist LY379268 reverses post-weaning social isolation-induced recognition memory deficits in the rat

(2010) Caitlin A. Jones et al.   PSYCHOPHARMACOLOGY

PROTEOMIC AND FUNCTIONAL ANALYSIS SUGGESTS THAT 5-HT6 RECEPTORS COMPROMISE COGNITION BY RECRUITING MTOR

(2010) Julie Meffre et al.   SCHIZOPHRENIA RESEARCH

Dimebolin is a 5-HT 6 antagonist with acute cognition enhancing activities

(2009) Hervé Schaffhauser et al.   BIOCHEMICAL PHARMACOLOGY

Impairment in Long-Term Retention of Preference Conditioning in Schizophrenia

(2009) Ellen S. Herbener   BIOLOGICAL PSYCHIATRY

Activation of the 5-HT6 receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus

(2009) P.J. West et al.   NEUROSCIENCE

Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia

(2009) Jared W. Young et al.   PHARMACOLOGY & THERAPEUTICS

Activation of 5-HT6 receptors facilitates attentional set shifting

(2009) Katherine E. Burnham et al.   PSYCHOPHARMACOLOGY

The effects of the 5-HT6 receptor agonist EMD and the 5-HT7 receptor agonist AS19 on memory formation

(2008) A. Meneses et al.   BEHAVIOURAL BRAIN RESEARCH

Fear conditioning in frontotemporal lobar degeneration and Alzheimer's disease

(2008) M. Hoefer et al.   BRAIN

Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat

(2008) B Marcos et al.   BRITISH JOURNAL OF PHARMACOLOGY

An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function

(2008) Kevin C.F. Fone   NEUROPHARMACOLOGY

5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer’s disease

(2008) Neil Upton et al.   Neurotherapeutics

Impact of regional 5-HT depletion on the cognitive enhancing effects of a typical 5-ht6 receptor antagonist, Ro 04-6790, in the Novel Object Discrimination task

(2008) M. V. King et al.   PSYCHOPHARMACOLOGY

A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory

(2008) M KING et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

On the participation of mTOR in recognition memory

(2007) Jociane C. Myskiw et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders

(2007) D.J. Heal et al.   PHARMACOLOGY & THERAPEUTICS

Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats

(2006) Angels Fisas et al.   BRITISH JOURNAL OF PHARMACOLOGY