Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins

GPCR Interacting Proteins (GIPs) in the Nervous System: Roles in Physiology and Pathologies

(2010) Joël Bockaert et al.   Annual Review of Pharmacology and Toxicology

Subtype-specific role of phospholipase C-β in bradykinin and LPA signaling through differential binding of different PDZ scaffold proteins

(2010) Jung Woong Choi et al.   CELLULAR SIGNALLING

Non-canonical functions of RGS proteins

(2010) Nan Sethakorn et al.   CELLULAR SIGNALLING

Beta-2 adrenergic receptor mediated ERK activation is regulated by interaction with MAGI-3

(2010) Xiaomei Yang et al.   FEBS LETTERS

Interaction of the Human Prostacyclin Receptor with Rab11

(2010) Helen M. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Na/H Exchanger Regulatory Factors Control Parathyroid Hormone Receptor Signaling by Facilitating Differential Activation of Gα Protein Subunits

(2010) Bin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabotropic Glutamate Receptor-Mediated Cell Signaling Pathways Are Altered in a Mouse Model of Huntington's Disease

(2010) F. M. Ribeiro et al.   JOURNAL OF NEUROSCIENCE

Homer-1 polymorphisms are associated with psychopathology and response to treatment in schizophrenic patients

(2010) Ilja Spellmann et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Phosphatidic Acid Plays a Regulatory Role in Clathrin-mediated Endocytosis

(2010) Costin N. Antonescu et al.   MOLECULAR BIOLOGY OF THE CELL

Role of Phospholipase D2/Phosphatidic Acid Signal Transduction in  - and  -Opioid Receptor Endocytosis

(2010) L. Yang et al.   MOLECULAR PHARMACOLOGY

Rab GTPases Bind at a Common Site within the Angiotensin II Type I Receptor Carboxyl-Terminal Tail: Evidence that Rab4 Regulates Receptor Phosphorylation, Desensitization, and Resensitization

(2010) J. L. Esseltine et al.   MOLECULAR PHARMACOLOGY

Thinking Outside of the "RGS Box": New Approaches to Therapeutic Targeting of Regulators of G Protein Signaling

(2010) B. Sjogren et al.   MOLECULAR PHARMACOLOGY

CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling

(2010) Ana C Magalhaes et al.   NATURE NEUROSCIENCE

Teaching old receptors new tricks: biasing seven-transmembrane receptors

(2010) Sudarshan Rajagopal et al.   NATURE REVIEWS DRUG DISCOVERY

Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling

(2010) L. M. Luttrell et al.   PHARMACOLOGICAL REVIEWS

The R7 RGS Protein Family: Multi-Subunit Regulators of Neuronal G Protein Signaling

(2009) Garret R. Anderson et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

PSD-95 regulates D1 dopamine receptor resensitization, but not receptor-mediated Gs-protein activation

(2009) Peihua Sun et al.   CELL RESEARCH

Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice

(2009) Julien Boeuf et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1

(2009) Ruth Dooley et al.   FEBS Journal

Synaptic Scaffolding Molecule Binds to and Regulates Vasoactive Intestinal Polypeptide Type-1 Receptor in Epithelial Cells

(2009) Heon Yung Gee et al.   GASTROENTEROLOGY

The PDZ domain protein CAL interacts with mGluR5a and modulates receptor expression

(2009) Shan Cheng et al.   JOURNAL OF NEUROCHEMISTRY

PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors

(2009) A. I. Abbas et al.   JOURNAL OF NEUROSCIENCE

The Small GTPase Ral Couples the Angiotensin II Type 1 Receptor to the Activation of Phospholipase C- 1

(2009) C. M. Godin et al.   MOLECULAR PHARMACOLOGY

NHERF1 Regulates Parathyroid Hormone Receptor Desensitization: Interference with  -Arrestin Binding

(2009) B. Wang et al.   MOLECULAR PHARMACOLOGY

Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling

(2009) K. A. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab11 regulates the recycling of the β2-adrenergic receptor through a direct interaction

(2008) Audrey Parent et al.   BIOCHEMICAL JOURNAL

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

(2008) B ZIMMERMAN et al.   CELLULAR SIGNALLING

A novel association of mGluR1a with the PDZ scaffold protein CAL modulates receptor activity

(2008) Jiuqin Zhang et al.   FEBS LETTERS

The PDZ Protein Mupp1 Promotes GiCoupling and Signaling of the Mt1Melatonin Receptor

(2008) Jean-Luc Guillaume et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homer Interactions Are Necessary for Metabotropic Glutamate Receptor-Induced Long-Term Depression and Translational Activation

(2008) J. A. Ronesi et al.   JOURNAL OF NEUROSCIENCE

Heptahelical Terpsichory. Who Calls the Tune?

(2008) DIANE GESTY-PALMER et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Physical Interaction of Calmodulin with the 5-Hydroxytryptamine2C Receptor C-Terminus Is Essential for G Protein-independent, Arrestin-dependent Receptor Signaling

(2008) Marilyne Labasque et al.   MOLECULAR BIOLOGY OF THE CELL

Reviews in Molecular Biology and Biotechnology: Transmembrane Signaling by G Protein-Coupled Receptors

(2008) Louis M. Luttrell   MOLECULAR BIOTECHNOLOGY

Regulation of Parathyroid Hormone Type 1 Receptor Dynamics, Traffic, and Signaling by the Na+/H+Exchanger Regulatory Factor-1 in Rat Osteosarcoma ROS 17/2.8 Cells

(2008) David Wheeler et al.   MOLECULAR ENDOCRINOLOGY

Multiple Actions of Spinophilin Regulate Mu Opioid Receptor Function

(2008) Joanna J. Charlton et al.   NEURON

Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5

(2008) J. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Location, location, location…site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

(2008) Andrew B. Tobin et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling

(2008) Muralidharan Jayaraman et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

G Protein–Coupled Receptor Sorting to Endosomes and Lysosomes

(2007) Adriano Marchese et al.   Annual Review of Pharmacology and Toxicology