标题
Inhibitory kappa B kinases as targets for pharmacological regulation
作者
关键词
-
出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 165, Issue 4, Pages 802-819
出版商
Wiley
发表日期
2011-07-28
DOI
10.1111/j.1476-5381.2011.01608.x
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tumor-Initiating and -Propagating Cells: Cells That We Would to Identify and Control
- (2015) Berit Bølge Tysnes NEOPLASIA
- Elucidating Substrate and Inhibitor Binding Sites on the Surface of GSK-3β and the Refinement of a Competitive Inhibitor
- (2011) Avital Licht-Murava et al. JOURNAL OF MOLECULAR BIOLOGY
- Crystal structure of inhibitor of κB kinase β
- (2011) Guozhou Xu et al. NATURE
- IKKβ Regulates the Repair of DNA Double-Strand Breaks Induced by Ionizing Radiation in MCF-7 Breast Cancer Cells
- (2011) Lixian Wu et al. PLoS One
- A homogeneous time-resolved fluorescence-based high-throughput screening system for discovery of inhibitors of IKKβ–NEMO interaction
- (2010) Yusuke Gotoh et al. ANALYTICAL BIOCHEMISTRY
- Inhibiting NF-κB activation by small molecules as a therapeutic strategy
- (2010) Subash C. Gupta et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
- (2010) Subash C. Gupta et al. CANCER AND METASTASIS REVIEWS
- Constitutive noncanonical NFκB signaling in pancreatic cancer cells
- (2010) Catherine E. Wharry et al. CANCER BIOLOGY & THERAPY
- TAK1 Suppresses a NEMO-Dependent but NF-κB-Independent Pathway to Liver Cancer
- (2010) Kira Bettermann et al. CANCER CELL
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- NF-κB in the regulation of epithelial homeostasis and inflammation
- (2010) Andy Wullaert et al. CELL RESEARCH
- IκB kinase β inhibitor IMD-0354 suppresses airway remodelling in a Dermatophagoides pteronyssinus-sensitized mouse model of chronic asthma
- (2010) H. Ogawa et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Paclitaxel Efficacy is Increased by Parthenolide via Nuclear Factor- KappaB Pathways in In Vitro and In Vivo Human Non – Small Cell Lung Cancer Models
- (2010) Z. W. Gao et al. CURRENT CANCER DRUG TARGETS
- Combination bortezomib and rituximab treatment affects multiple survival and death pathways to promote apoptosis in mantle cell lymphoma
- (2010) Lapo Alinari et al. mAbs
- Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation
- (2010) Robert Valentine et al. Molecular Cancer
- B-cell-derived lymphotoxin promotes castration-resistant prostate cancer
- (2010) Massimo Ammirante et al. NATURE
- 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors
- (2009) John Liddle et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Disulfiram/copper complex inhibiting NFκB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines
- (2009) Xiaoxia Guo et al. CANCER LETTERS
- Nuclear NF- B p65 Phosphorylation at Serine 276 by Protein Kinase A Contributes to the Malignant Phenotype of Head and Neck Cancer
- (2009) P. Arun et al. CLINICAL CANCER RESEARCH
- Effectiveness of IκB kinase inhibitors in murine colitis-associated tumorigenesis
- (2009) Yoku Hayakawa et al. JOURNAL OF GASTROENTEROLOGY
- Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β)
- (2009) John A. Christopher et al. JOURNAL OF MEDICINAL CHEMISTRY
- Addressing Reported Pro-Apoptotic Functions of NF-κB: Targeted Inhibition of Canonical NF-κB Enhances the Apoptotic Effects of Doxorubicin
- (2009) Brian K. Bednarski et al. PLoS One
- Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP
- (2009) Yifeng Xia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure-based design of molecular cancer therapeutics
- (2009) Rob L.M. van Montfort et al. TRENDS IN BIOTECHNOLOGY
- Cell-permeable Tat-NBD peptide attenuates rat pancreatitis and acinus cell inflammation response
- (2009) You-Ming Long et al. WORLD JOURNAL OF GASTROENTEROLOGY
- High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction
- (2008) Sumathy Mohan et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy
- (2008) Sanjeev Shangary et al. Annual Review of Pharmacology and Toxicology
- NEMO-binding domain peptide inhibits proliferation of human melanoma cells
- (2008) Angela Ianaro et al. CANCER LETTERS
- Advances in Targeting IKK and IKK-Related Kinases for Cancer Therapy
- (2008) D.-F. Lee et al. CLINICAL CANCER RESEARCH
- IKKα, a critical regulator of epidermal differentiation and a suppressor of skin cancer
- (2008) Pascal Descargues et al. EMBO JOURNAL
- Influence of TBK-1 on tumor angiogenesis and microvascular inflammation
- (2008) Marcus Czabanka Frontiers in Bioscience-Landmark
- Antiallergic and Anti-Inflammatory Effects of a Novel IκB Kinase β Inhibitor, IMD-0354, in a Mouse Model of Allergic Inflammation
- (2008) Akemi Sugita et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- How different are luminal A and basal breast cancers?
- (2008) François Bertucci et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of Human Immunodeficiency Virus Type 1 Replication by Blocking I B Kinase with Noraristeromycin
- (2008) K. Asamitsu et al. JOURNAL OF BIOCHEMISTRY
- KINK-1, a Novel Small-Molecule Inhibitor of IKKβ, and the Susceptibility of Melanoma Cells to Antitumoral Treatment
- (2008) Margarete Schön et al. JNCI-Journal of the National Cancer Institute
- Differential bortezomib sensitivity in head and neck cancer lines corresponds to proteasome, nuclear factor- B and activator protein-1 related mechanisms
- (2008) Z. Chen et al. MOLECULAR CANCER THERAPEUTICS
- SN52, a novel nuclear factor- B inhibitor, blocks nuclear import of RelB:p52 dimer and sensitizes prostate cancer cells to ionizing radiation
- (2008) Y. Xu et al. MOLECULAR CANCER THERAPEUTICS
- Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site
- (2008) Mia Rushe et al. STRUCTURE
- Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?
- (2008) Tieu-Lan Chau et al. TRENDS IN BIOCHEMICAL SCIENCES
- Inhibitors of c-Jun N-terminal kinases—JuNK no more?
- (2007) Marie A. Bogoyevitch et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Selective inhibition of inhibitory kappa B kinase-β abrogates induction of nitric oxide synthase in lipopolysaccharide-stimulated rat aortic smooth muscle cells
- (2005) Almudena Bermejo Gomez et al. BRITISH JOURNAL OF PHARMACOLOGY
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