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MicroRNAs: new players in acute myeloid leukaemia

期刊

BRITISH JOURNAL OF CANCER
卷 101, 期 5, 页码 743-748

出版社

NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6605232

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microRNAs; acute myeloid leukaemia; miRNA profiling; molecular alterations

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资金

  1. Belgian Fonds National de la Recherche Scientifique
  2. Kimmel Foundation for Cancer Research

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MicroRNAs (miRNAs) are short non-coding RNAs that have key functions in a wide array of critical cell processes, including haematopoiesis by regulating the expression of multiple genes. Aberrant miRNA expression has been described in acute myeloid leukaemia suggesting a role in leukaemogenesis. In this review we summarise the current knowledge. British Journal of Cancer (2009) 101, 743-748. doi:10.1038/sj.bjc.6605232 www.bjcancer.com Published online 11 August 2009 (C) 2009 Cancer Research UK

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