标题
Genomic insights into cancer-associated aberrant CpG island hypermethylation
作者
关键词
-
出版物
Briefings in Functional Genomics
Volume 12, Issue 3, Pages 174-190
出版商
Oxford University Press (OUP)
发表日期
2013-01-23
DOI
10.1093/bfgp/els063
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Programming of DNA Methylation Patterns
- (2012) Howard Cedar et al. Annual Review of Biochemistry
- 5-Methylcytosine DNA Demethylation: More Than Losing a Methyl Group
- (2012) Don-Marc Franchini et al. Annual Review of Genetics
- Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia
- (2012) A. F. T. Ribeiro et al. BLOOD
- Cancer Genetics and Epigenetics: Two Sides of the Same Coin?
- (2012) Jueng Soo You et al. CANCER CELL
- DNA Methylation Screening Identifies Driver Epigenetic Events of Cancer Cell Survival
- (2012) Daniel D. De Carvalho et al. CANCER CELL
- Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma
- (2012) Christine Guo Lian et al. CELL
- The Origin and Evolution of Mutations in Acute Myeloid Leukemia
- (2012) John S. Welch et al. CELL
- Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs
- (2012) Emily Brookes et al. Cell Stem Cell
- Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome
- (2012) Anne-Valerie Gendrel et al. DEVELOPMENTAL CELL
- Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells
- (2012) T. Clouaire et al. GENES & DEVELOPMENT
- D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
- (2012) M. Sasaki et al. GENES & DEVELOPMENT
- Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA
- (2012) Aaron L. Statham et al. GENOME RESEARCH
- Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk
- (2012) Arie B. Brinkman et al. GENOME RESEARCH
- A DNA hypermethylation module for the stem/progenitor cell signature of cancer
- (2012) H. Easwaran et al. GENOME RESEARCH
- DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells
- (2012) Christoph Bock et al. MOLECULAR CELL
- Resolving the stem-cell debate
- (2012) Richard J. Gilbertson et al. NATURE
- IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
- (2012) Masato Sasaki et al. NATURE
- The DNA damage response and cancer therapy
- (2012) Christopher J. Lord et al. NATURE
- The accessible chromatin landscape of the human genome
- (2012) Robert E. Thurman et al. NATURE
- Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
- (2012) Gilad Landan et al. NATURE GENETICS
- DNA methylation profiling in the clinic: applications and challenges
- (2012) Holger Heyn et al. NATURE REVIEWS GENETICS
- Functions of DNA methylation: islands, start sites, gene bodies and beyond
- (2012) Peter A. Jones NATURE REVIEWS GENETICS
- Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression
- (2012) Z.-Q. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
- (2012) S. Ruiz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns
- (2012) Duncan Sproul et al. GENOME BIOLOGY
- The role of methyl-binding proteins in chromatin organization and epigenome maintenance
- (2011) A. Fournier et al. Briefings in Functional Genomics
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Dominantly Inherited Constitutional Epigenetic Silencing of MLH1 in a Cancer-Affected Family Is Linked to a Single Nucleotide Variant within the 5′UTR
- (2011) Megan P. Hitchins et al. CANCER CELL
- 5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations
- (2011) S.-G. Jin et al. CANCER RESEARCH
- An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment
- (2011) Magnus D Lynch et al. EMBO JOURNAL
- Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function
- (2011) Ditsa Levanon et al. EMBO Molecular Medicine
- Regulation of mammalian DNA methyltransferases: a route to new mechanisms
- (2011) Hélène Denis et al. EMBO REPORTS
- DNA methylation: TET proteins—guardians of CpG islands?
- (2011) Kristine Williams et al. EMBO REPORTS
- CpG islands and the regulation of transcription
- (2011) A. M. Deaton et al. GENES & DEVELOPMENT
- Cell type-specific DNA methylation at intragenic CpG islands in the immune system
- (2011) A. M. Deaton et al. GENOME RESEARCH
- Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
- (2011) G. C. Hon et al. GENOME RESEARCH
- Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes
- (2011) C. E. Nestor et al. GENOME RESEARCH
- Genome-scale analysis of aberrant DNA methylation in colorectal cancer
- (2011) T. Hinoue et al. GENOME RESEARCH
- Methylation dynamics of IG-DMR and Gtl2-DMR during murine embryonic and placental development
- (2011) Shun Sato et al. GENOMICS
- Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer
- (2011) Eveline J. Steine et al. JOURNAL OF CLINICAL INVESTIGATION
- Recurrent DNMT3A mutations in patients with myelodysplastic syndromes
- (2011) M J Walter et al. LEUKEMIA
- TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
- (2011) Kristine Williams et al. NATURE
- Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
- (2011) Hao Wu et al. NATURE
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
- (2011) Benjamin P Berman et al. NATURE GENETICS
- Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
- (2011) Xiao-Jing Yan et al. NATURE GENETICS
- Identification of genetic elements that autonomously determine DNA methylation states
- (2011) Florian Lienert et al. NATURE GENETICS
- Epigenome-wide association studies for common human diseases
- (2011) Vardhman K. Rakyan et al. NATURE REVIEWS GENETICS
- Genomics and the Continuum of Cancer Care
- (2011) Ultan McDermott et al. NEW ENGLAND JOURNAL OF MEDICINE
- Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
- (2011) Beth O. Van Emburgh et al. NUCLEIC ACIDS RESEARCH
- DNA hypermethylation in lung cancer is targeted at differentiation-associated genes
- (2011) E Helman et al. ONCOGENE
- Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
- (2011) D. Sproul et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis
- (2011) F. Fang et al. Science Translational Medicine
- Generation of bivalent chromatin domains during cell fate decisions
- (2011) Marco De Gobbi et al. Epigenetics & Chromatin
- Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation
- (2011) Jason Gertz et al. PLoS Genetics
- Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types
- (2011) Michael J. Ziller et al. PLoS Genetics
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- DNMT3B7, a Truncated DNMT3B Isoform Expressed in Human Tumors, Disrupts Embryonic Development and Accelerates Lymphomagenesis
- (2010) M. Y. Shah et al. CANCER RESEARCH
- General Transcription Factor Binding at CpG Islands in Normal Cells Correlates with Resistance to De novo DNA Methylation in Cancer Cells
- (2010) C. Gebhard et al. CANCER RESEARCH
- Unique DNA Methylation Patterns Distinguish Noninvasive and Invasive Urothelial Cancers and Establish an Epigenetic Field Defect in Premalignant Tissue
- (2010) E. M. Wolff et al. CANCER RESEARCH
- A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs
- (2010) Jonghwan Kim et al. CELL
- Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
- (2010) Eric Hervouet et al. Epigenetics
- Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation
- (2010) Margaret Rush et al. Epigenetics
- Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis
- (2010) M. L. Conerly et al. GENOME RESEARCH
- Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer
- (2010) M. R. H. Estecio et al. GENOME RESEARCH
- Polycomb preferentially targets stalled promoters of coding and noncoding transcripts
- (2010) D. Enderle et al. GENOME RESEARCH
- Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression
- (2010) A. E. K. Ibrahim et al. GUT
- BRCA1 CpG Island Hypermethylation Predicts Sensitivity to Poly(Adenosine Diphosphate)- Ribose Polymerase Inhibitors
- (2010) Jurgen Veeck et al. JOURNAL OF CLINICAL ONCOLOGY
- Histological types of breast cancer: How special are they?
- (2010) Britta Weigelt et al. Molecular Oncology
- Comprehensive methylome map of lineage commitment from haematopoietic progenitors
- (2010) Hong Ji et al. NATURE
- CpG islands influence chromatin structure via the CpG-binding protein Cfp1
- (2010) John P. Thomson et al. NATURE
- DNMT3AMutations in Acute Myeloid Leukemia
- (2010) Timothy J. Ley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme
- (2010) Katan Patel et al. NUCLEIC ACIDS RESEARCH
- DNA Methylation Profiles of Ovarian Epithelial Carcinoma Tumors and Cell Lines
- (2010) Sahar Houshdaran et al. PLoS One
- Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation
- (2010) A. Zemach et al. SCIENCE
- Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome
- (2010) Robert S. Illingworth et al. PLoS Genetics
- Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
- (2009) O. Abdel-Wahab et al. BLOOD
- Adenomatous polyposis coli 1A is likely to be methylated as a passenger in human gastric carcinogenesis
- (2009) Kosuke Hosoya et al. CANCER LETTERS
- Lessons from comparative analysis of X-chromosome inactivation in mammals
- (2009) Ikuhiro Okamoto et al. CHROMOSOME RESEARCH
- Methylation not a frequent “second hit” in tumors with germline BRCA mutations
- (2009) Amy M. Dworkin et al. Familial Cancer
- The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands
- (2009) H. Takeshima et al. GENOME RESEARCH
- Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning
- (2009) Rebecca A. Hinshelwood et al. HUMAN MOLECULAR GENETICS
- Array-based DNA methylation profiling in follicular lymphoma
- (2009) C O'Riain et al. LEUKEMIA
- The cancer genome
- (2009) Michael R. Stratton et al. NATURE
- The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
- (2009) Rafael A Irizarry et al. NATURE GENETICS
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
- (2009) S. Kriaucionis et al. SCIENCE
- DNA hypomethylation in cancer cells
- (2009) Melanie Ehrlich Epigenomics
- CpG island methylator phenotype (CIMP) in cancer: Causes and implications
- (2008) Jens M. Teodoridis et al. CANCER LETTERS
- Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation
- (2008) Shaun D. Fouse et al. Cell Stem Cell
- CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
- (2008) S. Ogino et al. GUT
- DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status
- (2008) B L Pike et al. LEUKEMIA
- Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors
- (2008) Fabio Mohn et al. MOLECULAR CELL
- Dissecting direct reprogramming through integrative genomic analysis
- (2008) Tarjei S. Mikkelsen et al. NATURE
- Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
- (2008) Daniel Zilberman et al. NATURE
- Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
- (2008) Yutaka Kondo et al. NATURE GENETICS
- Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1
- (2008) Marjolijn J L Ligtenberg et al. NATURE GENETICS
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
- (2008) Ittai Ben-Porath et al. NATURE GENETICS
- DNA methylation landscapes: provocative insights from epigenomics
- (2008) Miho M. Suzuki et al. NATURE REVIEWS GENETICS
- De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
- (2008) Silvina Epsztejn-Litman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
- (2008) E. N. Gal-Yam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Sp1/Sp3 Binding Polymorphism Confers Methylation Protection
- (2008) Yanis A. Boumber et al. PLoS Genetics
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