期刊
JOURNAL OF CLINICAL PERIODONTOLOGY
卷 42, 期 8, 页码 733-739出版社
WILEY
DOI: 10.1111/jcpe.12421
关键词
body mass index; obesity; overweight; periodontitis
资金
- Department of Health's NIHR Biomedical Research Centres funding scheme
- UK Clinical Research Collaboration
ObjectiveTo investigate periodontitis as a co-morbidity of overweight/obesity in an age-matched sample of periodontitis cases or periodontally healthy controls. MethodsParticipants were periodontally assessed using whole mouth clinical periodontal measures. Multivariable conditional logistic regression was used to calculate the odds ratio for diagnosis of periodontitis when body mass index (kg/m(2)), overweight (BMI 25-29.99kg/m(2), or obese BMI30kg/m(2)) were the explanatory variables. A receiver operating characteristic (ROC) curve was generated of all possible BMI (kg/m(2)) cut-off points discriminating individuals for diagnosis of periodontitis. ResultsThe study comprised 286 participants. BMI showed a dose-response association with increased odds (1.12 per increase of 1kg/m(2), 95% CI 1.05-1.20, p=0.001) of being a case compared to a control independent of gender, ethnicity, smoking status and dental plaque level. Similarly overweight/obese were independently associated with increased odds of diagnosis of periodontitis for overweight (OR=2.56, 95% CI 1.210-5.400, p=0.014) and for obese (OR=3.11, 95% CI 1.052-6.481, p=0.015) compared to normal weight individuals. The ROC curve analysis confirmed diagnosis of periodontitis was 1.6 times more likely in an individual with the BMI24.32kg/m(2). ConclusionsOverweight/obese individuals are more likely to suffer from periodontitis compared to normal weight individuals in this case-control sample.
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