标题
Insights from systems pharmacology into cardiovascular drug discovery and therapy
作者
关键词
Cardiovascular disease, Network pharmacology, Network analysis, Drug discovery, Drug-target network, Gene-disease network
出版物
BMC Systems Biology
Volume 8, Issue 1, Pages -
出版商
Springer Nature
发表日期
2014-12-23
DOI
10.1186/s12918-014-0141-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Target identification and mechanism of action in chemical biology and drug discovery
- (2013) Monica Schenone et al. Nature Chemical Biology
- Structure and dynamics of molecular networks: A novel paradigm of drug discovery
- (2013) Peter Csermely et al. PHARMACOLOGY & THERAPEUTICS
- A systematic identification of multiple toxin–target interactions based on chemical, genomic and toxicological data
- (2013) Wei Zhou et al. TOXICOLOGY
- HINT: High-quality protein interactomes and their applications in understanding human disease
- (2012) Jishnu Das et al. BMC Systems Biology
- The Emerging Paradigm of Network Medicine in the Study of Human Disease
- (2012) Stephen Y. Chan et al. CIRCULATION RESEARCH
- Deciphering the molecular basis of human cardiovascular disease through network biology
- (2012) Stephen Y. Chan et al. CURRENT OPINION IN CARDIOLOGY
- Automated design of ligands to polypharmacological profiles
- (2012) Jérémy Besnard et al. NATURE
- Systems-based approaches to cardiovascular disease
- (2012) W. Robb MacLellan et al. Nature Reviews Cardiology
- Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development
- (2012) K. Lage et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Challenges and Opportunities for Cardiovascular Disease Prevention
- (2011) Manuel Franco et al. AMERICAN JOURNAL OF MEDICINE
- Novel Computational Approaches to Polypharmacology as a Means to Define Responses to Individual Drugs
- (2011) Lei Xie et al. Annual Review of Pharmacology and Toxicology
- Systems Pharmacology: Network Analysis to Identify Multiscale Mechanisms of Drug Action
- (2011) Shan Zhao et al. Annual Review of Pharmacology and Toxicology
- Strategic Approaches to Unraveling Genetic Causes of Cardiovascular Diseases
- (2011) A.J. Marian et al. CIRCULATION RESEARCH
- Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery
- (2011) F. Zhu et al. NUCLEIC ACIDS RESEARCH
- Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases
- (2011) Anna Bauer-Mehren et al. PLoS One
- Cardiovascular Networks
- (2010) Aldons J. Lusis et al. CIRCULATION
- Rational approaches to targeted polypharmacology: creating and navigating protein–ligand interaction networks
- (2010) James T Metz et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins
- (2010) Guillaume Pidoux et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Dissecting spatio-temporal protein networks driving human heart development and related disorders
- (2010) Kasper Lage et al. Molecular Systems Biology
- Accelerating the pulse of cardiovascular R&D
- (2010) Andrew Plump NATURE REVIEWS DRUG DISCOVERY
- DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs
- (2010) C. Knox et al. NUCLEIC ACIDS RESEARCH
- Unveiling the role of network and systems biology in drug discovery
- (2010) Albert Pujol et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The analysis of the drug–targets based on the topological properties in the human protein–protein interaction network
- (2009) Mingzhu Zhu et al. JOURNAL OF DRUG TARGETING
- The impact of cellular networks on disease comorbidity
- (2009) Juyong Park et al. Molecular Systems Biology
- An Uncertain Future for Cardiovascular Drug Development?
- (2009) Alan M. Garber NEW ENGLAND JOURNAL OF MEDICINE
- Human Disease-Drug Network Based on Genomic Expression Profiles
- (2009) Guanghui Hu et al. PLoS One
- A Dynamic Network Approach for the Study of Human Phenotypes
- (2009) César A. Hidalgo et al. PLoS Computational Biology
- Fast Gene Ontology based clustering for microarray experiments
- (2009) Kristian Ovaska et al. BioData Mining
- Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone
- (2008) M J Forrest et al. BRITISH JOURNAL OF PHARMACOLOGY
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- The implications of human metabolic network topology for disease comorbidity
- (2008) D.- S. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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