Photo-sensitive degron variants for tuning protein stability by light

Biophysical, Mutational, and Functional Investigation of the Chromophore-Binding Pocket of Light-Oxygen-Voltage Photoreceptors

(2014) Ralph P. Diensthuber et al.   ACS Synthetic Biology

General Method for Regulating Protein Stability with Light

(2013) Kimberly M. Bonger et al.   ACS Chemical Biology

Coiled-coil dimerization of the LOV2 domain of the blue-light photoreceptor phototropin 1 fromArabidopsis thaliana

(2013) Andrei S. Halavaty et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Investigating Models of Protein Function and Allostery With a Widespread Mutational Analysis of a Light-Activated Protein

(2013) Josiah P. Zayner et al.   BIOPHYSICAL JOURNAL

A LOV2 Domain-Based Optogenetic Tool to Control Protein Degradation and Cellular Function

(2013) Christian Renicke et al.   CHEMISTRY & BIOLOGY

Charting the Signal Trajectory in a Light-Oxygen-Voltage Photoreceptor by Random Mutagenesis and Covariance Analysis

(2013) Tobias Gleichmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Tobacco Etch Virus Protease with Increased Substrate Tolerance at the P1' position

(2013) Christian Renicke et al.   PLoS One

Visible light alters yeast metabolic rhythms by inhibiting respiration

(2013) J. B. Robertson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MAL

(2013) C. Baarlink et al.   SCIENCE

Light-Induced Subunit Dissociation by a Light–Oxygen–Voltage Domain Photoreceptor from Rhodobacter sphaeroides

(2012) Karen S. Conrad et al.   BIOCHEMISTRY

Controlling the DNA Cleavage Activity of Light-Inducible Chimeric Endonucleases by Bidirectional Photoactivation

(2012) Benno Schierling et al.   BIOCONJUGATE CHEMISTRY

Designing Photoswitchable Peptides Using the AsLOV2 Domain

(2012) Oana I. Lungu et al.   CHEMISTRY & BIOLOGY

Mutations in N-terminal Flanking Region of Blue Light-sensing Light-Oxygen and Voltage 2 (LOV2) Domain Disrupt Its Repressive Activity on Kinase Domain in the Chlamydomonas Phototropin

(2012) Yusuke Aihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Amino-Terminal Helix Modulates Light-Activated Conformational Changes in AsLOV2

(2012) Josiah P. Zayner et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for the Slow Dark Recovery of a Full-Length LOV Protein from Pseudomonas putida

(2012) Franco Circolone et al.   JOURNAL OF MOLECULAR BIOLOGY

From Dusk till Dawn: One-Plasmid Systems for Light-Regulated Gene Expression

(2012) Robert Ohlendorf et al.   JOURNAL OF MOLECULAR BIOLOGY

Light-Inducible Spatiotemporal Control of Gene Activation by Customizable Zinc Finger Transcription Factors

(2012) Lauren R. Polstein et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TULIPs: tunable, light-controlled interacting protein tags for cell biology

(2012) Devin Strickland et al.   NATURE METHODS

A Synthetic Approach Reveals Extensive Tunability of Auxin Signaling

(2012) K. A. Havens et al.   PLANT PHYSIOLOGY

Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells

(2012) A. J. Holland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic Control of Cells and Circuits

(2011) Gero Miesenböck   Annual Review of Cell and Developmental Biology

Variations in Protein–Flavin Hydrogen Bonding in a Light, Oxygen, Voltage Domain Produce Non-Arrhenius Kinetics of Adduct Decay

(2011) Brian D. Zoltowski et al.   BIOCHEMISTRY

Dependence of Proteasome Processing Rate on Substrate Unfolding

(2011) Allen Henderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of the Photocycle of a LOV Domain Photoreceptor by the Hydrogen-Bonding Network

(2011) Sarah Raffelberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tripping the Light Fantastic: Blue-Light Photoreceptors as Examples of Environmentally Modulated Protein−Protein Interactions

(2010) Brian D. Zoltowski et al.   BIOCHEMISTRY

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

(2010) Jared E Toettcher et al.   NATURE METHODS

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Rationally improving LOV domain–based photoswitches

(2010) Devin Strickland et al.   NATURE METHODS

Mutual Exchange of Kinetic Properties by Extended Mutagenesis in Two Short LOV Domain Proteins fromPseudomonas putida

(2009) Katrin Jentzsch et al.   BIOCHEMISTRY

Protein Sectors: Evolutionary Units of Three-Dimensional Structure

(2009) Najeeb Halabi et al.   CELL

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Mechanism-based tuning of a LOV domain photoreceptor

(2009) Brian D Zoltowski et al.   Nature Chemical Biology

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

A switchable light-input, light-output system modelled and constructed in yeast

(2009) Oxana Sorokina et al.   Journal of Biological Engineering

TinkerCell: modular CAD tool for synthetic biology

(2009) Deepak Chandran et al.   Journal of Biological Engineering

Structural elements of the ubiquitin-independent proteasome degron of ornithine decarboxylase

(2008) Junko Takeuchi et al.   BIOCHEMICAL JOURNAL

Estimation of the available free energy in a LOV2-Jα photoswitch

(2008) Xiaolan Yao et al.   Nature Chemical Biology

Light-activated DNA binding in a designed allosteric protein

(2008) D. Strickland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA