Optogenetic Control of Cells and Circuits

Active Expiration Induced by Excitation of Ventral Medulla in Adult Anesthetized Rats

(2011) S. Pagliardini et al.   JOURNAL OF NEUROSCIENCE

Functional identification of an aggression locus in the mouse hypothalamus

(2011) Dayu Lin et al.   NATURE

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

Ultra light-sensitive and fast neuronal activation with the Ca2+-permeable channelrhodopsin CatCh

(2011) Sonja Kleinlogel et al.   NATURE NEUROSCIENCE

Habenula “Cholinergic” Neurons Corelease Glutamate and Acetylcholine and Activate Postsynaptic Neurons via Distinct Transmission Modes

(2011) Jing Ren et al.   NEURON

Optical Control of Neuronal Activity

(2010) Stephanie Szobota et al.   Annual Review of Biophysics

Structure and Function of Plant Photoreceptors

(2010) Andreas Möglich et al.   Annual Review of Plant Biology

Tripping the Light Fantastic: Blue-Light Photoreceptors as Examples of Environmentally Modulated Protein−Protein Interactions

(2010) Brian D. Zoltowski et al.   BIOCHEMISTRY

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Optogenetic Approaches in Neuroscience

(2010) André Fiala et al.   CURRENT BIOLOGY

Natural and Engineered Photoactivated Nucleotidyl Cyclases for Optogenetic Applications

(2010) Min-Hyung Ryu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil BacteriumBeggiatoa

(2010) Manuela Stierl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toward the Second Generation of Optogenetic Tools

(2010) T. Knopfel et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Localization and Genetic Perturbation of Saccade-Generating Neurons in Zebrafish

(2010) P. J. Schoonheim et al.   JOURNAL OF NEUROSCIENCE

Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP

(2010) Andrei V. Karginov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit

(2010) Keisuke Yonehara et al.   NATURE

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Genetic dissection of an amygdala microcircuit that gates conditioned fear

(2010) Wulf Haubensak et al.   NATURE

Encoding of conditioned fear in central amygdala inhibitory circuits

(2010) Stephane Ciocchi et al.   NATURE

Optogenetic control of heart muscle in vitro and in vivo

(2010) Tobias Bruegmann et al.   NATURE METHODS

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Rationally improving LOV domain–based photoswitches

(2010) Devin Strickland et al.   NATURE METHODS

A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing

(2010) Harald Janovjak et al.   NATURE NEUROSCIENCE

Tuning arousal with optogenetic modulation of locus coeruleus neurons

(2010) Matthew E Carter et al.   NATURE NEUROSCIENCE

Network mechanisms of theta related neuronal activity in hippocampal CA1 pyramidal neurons

(2010) Attila Losonczy et al.   NATURE NEUROSCIENCE

The columnar and laminar organization of inhibitory connections to neocortical excitatory cells

(2010) Dennis Kätzel et al.   NATURE NEUROSCIENCE

Ultrafast optogenetic control

(2010) Lisa A Gunaydin et al.   NATURE NEUROSCIENCE

Non-redundant odor coding by sister mitral cells revealed by light addressable glomeruli in the mouse

(2010) Ashesh K Dhawale et al.   NATURE NEUROSCIENCE

Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling

(2010) Alex C Koon et al.   NATURE NEUROSCIENCE

Pathway-Specific Feedforward Circuits between Thalamus and Neocortex Revealed by Selective Optical Stimulation of Axons

(2010) Scott J. Cruikshank et al.   NEURON

Single-Cell Optogenetic Excitation Drives Homeostatic Synaptic Depression

(2010) Carleton P. Goold et al.   NEURON

Optogenetic Control of Cardiac Function

(2010) A. B. Arrenberg et al.   SCIENCE

Motor Control by Sensory Cortex

(2010) F. Matyas et al.   SCIENCE

Astrocytes Control Breathing Through pH-Dependent Release of ATP

(2010) A. V. Gourine et al.   SCIENCE

Tracking Stem Cell Differentiation in the Setting of Automated Optogenetic Stimulation

(2010) Albrecht Stroh et al.   STEM CELLS

Structure and Insight into Blue Light-Induced Changes in the BlrP1 BLUF Domain†,‡

(2009) Qiong Wu et al.   BIOCHEMISTRY

Structural Guidance of the Photocycle of Channelrhodopsin-2 by an Interhelical Hydrogen Bond

(2009) Christian Bamann et al.   BIOCHEMISTRY

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

Writing Memories with Light-Addressable Reinforcement Circuitry

(2009) Adam Claridge-Chang et al.   CELL

What Makes the Difference between a Cryptochrome and DNA Photolyase? A Spectroelectrochemical Comparison of the Flavin Redox Transitions

(2009) Véronique Balland et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

The subcellular organization of neocortical excitatory connections

(2009) Leopoldo Petreanu et al.   NATURE

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Electrophysiology in the age of light

(2009) Massimo Scanziani et al.   NATURE

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

Optogenetic dissection of a behavioural module in the vertebrate spinal cord

(2009) Claire Wyart et al.   NATURE

Induction of protein-protein interactions in live cells using light

(2009) Masayuki Yazawa et al.   NATURE BIOTECHNOLOGY

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE

PINP: A New Method of Tagging Neuronal Populations for Identification during In Vivo Electrophysiological Recording

(2009) Susana Q. Lima et al.   PLoS One

Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR

(2009) R. Numano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical control of zebrafish behavior with halorhodopsin

(2009) A. B. Arrenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Channelrhodopsin-2 is a leaky proton pump

(2009) K. Feldbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical Deconstruction of Parkinsonian Neural Circuitry

(2009) V. Gradinaru et al.   SCIENCE

The Optogenetic Catechism

(2009) G. Miesenbock   SCIENCE

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Lighting up the Brain

(2009) Gero Miesenböck   SCIENTIFIC AMERICAN

Algal Sensory Photoreceptors

(2008) Peter Hegemann   Annual Review of Plant Biology

Decoding of Light Signals by Plant Phytochromes and Their Interacting Proteins

(2008) Gabyong Bae et al.   Annual Review of Plant Biology

Sex-Specific Control and Tuning of the Pattern Generator for Courtship Song in Drosophila

(2008) J. Dylan Clyne et al.   CELL

Photocontrol of Neural Activity: Biophysical Mechanisms and Performancein Vivo

(2008) Lucas Sjulson et al.   CHEMICAL REVIEWS

Escape Behavior Elicited by Single, Channelrhodopsin-2-Evoked Spikes in Zebrafish Somatosensory Neurons

(2008) Adam D. Douglass et al.   CURRENT BIOLOGY

Monitoring Light-induced Structural Changes of Channelrhodopsin-2 by UV-visible and Fourier Transform Infrared Spectroscopy

(2008) Eglof Ritter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Conclusive Mechanism of the Photoinduced Reaction Cascade in Blue Light Using Flavin Photoreceptors

(2008) Keyarash Sadeghian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hidden female talent

(2008) Jai Y. Yu et al.   NATURE

Estimation of the available free energy in a LOV2-Jα photoswitch

(2008) Xiaolan Yao et al.   Nature Chemical Biology

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

(2008) Feng Zhang et al.   NATURE NEUROSCIENCE

Nanoengineering Ion Channels for Optical Control

(2008) Pau Gorostiza et al.   PHYSIOLOGY

Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway

(2008) D. W. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Light-activated DNA binding in a designed allosteric protein

(2008) D. Strickland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical Switches for Remote and Noninvasive Control of Cell Signaling

(2008) P. Gorostiza et al.   SCIENCE

Photoexcited CRY2 Interacts with CIB1 to Regulate Transcription and Floral Initiation in Arabidopsis

(2008) H. Liu et al.   SCIENCE

Spectral Characteristics of the Photocycle of Channelrhodopsin-2 and Its Implication for Channel Function

(2007) Christian Bamann et al.   JOURNAL OF MOLECULAR BIOLOGY

Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice

(2007) Daniel Huber et al.   NATURE